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Pure Urolithin A
Purity: 98%
Appearance: Light Yellow Powder
CAS：1143-70-0
Molecular Formula :C13H8O4
Molecular Weight: 228.20
Solubility: Soluble in DMSO (20 mg/mL)
Top quality, Competitive price, Best service
Storage conditions: This product should be sealed and shaded, stored in a dry
Certifications:ISO9001,ISO22000,Kosher,Halal,HACCP
Shipping speed:1-3 days
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Product Introduction
What is Urolithin A Powder?
Urolithin A (UA) is a naturally occurring active product of ellagitannins metabolized by gut microbiota. It is mainly found in foods such as pomegranates, berries, and nuts. Its effects on activating autophagy, improving mitochondrial function, and anti-aging have garnered significant attention. YTBIO supplies urolithin A with a purity of 98%, which can be widely used in the development of anti-aging dietary supplements, sports nutrition products, and functional foods. All our production processes strictly adhere to international certification systems such as cGMP, FSSC2200, BRC, HACCP, HALAL, KOSHER, ISO9001, and ISO22000, ensuring batch traceability and data verification.
| ITEM | STANDARD | TEST RESULT |
|---|---|---|
| Purity (HPLC) | ≥98.0% | 99.78% |
| Physical & Chemical | ||
| Appearance | Beige to yellow powder | Complies |
| Identification | ¹H NMR confirms to structure | Complies |
| LCMS | LCMS Conforms to MW | Complies |
| Water | ≤0.5% | 0.11% |
| Sulphated Ash | ≤0.1% | Complies |
| Residue on Ignition | ≤0.1% | 0.05% |
| Heavy Metals | ||
| As | ≤1.5ppm | Complies |
| Cd | ≤0.5ppm | Complies |
| Pb | ≤0.5ppm | Complies |
| Hg | ≤0.1ppm | Complies |
| Residual solvents | ||
| Methanol | ≤3,000ppm | Negative |
| TBME | ≤1,000ppm | Negative |
| Toluene | ≤890.0ppm | Negative |
| DMSO | ≤5,000ppm | 3970ppm |
| Acetic Acid | ≤5,000ppm | 1520ppm |
| Conclusion | Conform with specification | |
| Storage | Store in cool and dry places. Keep away from strong light and heat. | |
| Packing | 1kg/bag, inner by double plastic bag | |
| Shelf Life | 24 months under the above condition, and in it’s original package |
How does urolithin A achieve anti-aging?
The most consistent effect of urolithin A across species is improving mitochondrial health, an effect observed in experiments in cells, worms, mice and humans. This benefit is caused by the clearance of dysfunctional mitochondria and mitophagy, a selective autophagy process called mitophagy.
With aging and some age-related diseases, mitophagy is impaired. Restoring normal functional mitophagy levels is a promising way to counteract age-related decline in organ function.
When mitochondria are damaged or exposed to external mitophagy inducers, mitophagy will occur. When autophagy is damaged, urolithin A regulates through two regulatory pathways to restore mitophagy and produce autophagy. Phagosome vesicles engulf damaged mitochondria and combine with lysosomes to normalize the entire mitophagy function.
Mitochondria are often called the engines of energy sources, and the role of urolithin A is to clean them in time when the engines are damaged and need to be scrapped, and transported to the treatment plant for scrapping. At the same time, the cell factory produces new mitochondrial generators.
Which Foods Contain Urolithin A ?
Foods high in this nutrient are rare, because UA is a postbiotic derived by our microbiota. What you'll discover instead are meals high in polyphenols that can be turned into UA, called ellagic acid and ellagitannins.
Walnuts, pomegranates, strawberries, raspberries, blackberries, and some varieties of red wine stored in oak barrels are among the main foods that contain ellagitannins. Ellagitannins, which are present in these natural sources in different amounts, can help the gut bacteria produce urolithin A.
What Is Urolithin A Benefits ?
1) Its ability to support mitochondrial function and health has been researched. The lifeblood of cells, mitochondria are essential to general cellular health because of their efficient operation.
2) Urolitin A may help maintain the health and function of muscles, boosting muscle regeneration and slowing down age-related muscle deterioration, according to available data.
3) The substance has been studied for its anti-inflammatory qualities that may have advantages for general health and wellness.
4) While further research is required, some studies have looked into the possibility to promote longevity and healthy aging.
What are the applications of Urolithin A?
Urolithin A, due to its bioactivity, shows broad application potential in pharmaceuticals, health supplements, and cosmetics:
In the pharmaceutical field, it provides new insights into the adjunctive treatment of ischemic heart diseases such as coronary heart disease and myocardial infarction by promoting angiogenesis and improving microcirculation; its mechanism of action in inhibiting the release of inflammatory mediators also gives it clear value in the development of anti-inflammatory drugs.
In the health supplement field, urolithin A is widely used in anti-aging dietary supplements, sports nutrition products, and immune support products.
In the cosmetics field, urolithin A mainly delays skin aging by scavenging free radicals and reducing UV-induced oxidative damage; at the same time, it can promote the renewal and repair of keratinocytes and fibroblasts, improving skin texture and elasticity, making it suitable for anti-wrinkle and repair serums and creams.
YTBIO is committed to providing customers with the highest-quality Pure urolithin A powder bulk and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.
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