Sodium Alginate Bulk

What is Sodium Alginate Powder?

Sodium alginate, also known as sodium alginate, kelp gum, alginate, is a kind of kelp and seaweed as raw materials through various ion exchanges (digestion, filtration, bleaching and calcification, decalcification, neutralization transformation) Natural chain-like high molecular polysaccharide polymer extracted. The production of sodium alginate in my country is mainly concentrated in coastal areas. Coastal areas are rich in seaweed resources. Sodium alginate Bulk production has developed rapidly. The current production volume is about 11kt (including industrial grade), and the proportion of food grade is increasing year by year. Domestic production is mainly concentrated in coastal areas such as Qingdao, and there are currently about 20 domestic manufacturers. Due to its unique thickening, hydrophilicity, stability, gelling, oil resistance, film-forming properties, sodium alginate is widely used in various industries.

YTBIO Pure sodium alginate is a white powder that is almost odorless and non-toxic. Sodium alginate is slightly soluble in water, soluble in alkaline solutions, and insoluble in most organic solvents. Sodium alginate easily absorbs moisture. The high-viscosity sodium alginate molecular chain is unstable and easily degraded. Sodium alginate solution can complex metal divalent ions to form a gel. YTBIO sodium alginate is a natural polysaccharide with the stability, solubility, viscosity and safety required for pharmaceutical preparation excipients. The special structure of sodium alginate molecules enables it to thicken, emulsify, form gels, and have good biocompatibility. It is widely used in food, medicine, water treatment and other fields.

Physical and chemical properties of sodium alginate

The molecular formula of Sodium Alginate Bulk is C5H7O4COONa, the theoretical molecular weight is 198.11, the average actual molecular weight is 222.00, and the degree of polymerization is 80~750. It is a white or light yellow powder, odorless, and almost insoluble in organic agents such as ethanol and ether.

water solubility

When sodium alginate dissolves in water, it forms a viscous colloid, which can expand 10 times in volume after absorbing water. The viscosity of its aqueous solution mainly changes with the degree of polymerization and concentration. Since sodium alginate solution maintains negative ion groups, it has an opposing charge and has a coagulation effect on hydrophobic suspensions. It is often used as a thickening agent in food.

Stability

Pure Sodium Alginate will gradually form alginic acid gel when the pH is lowered. When the pH is raised, the alginic acid will dissolve and return to its original viscosity; Alkali resistance: Sodium alginate can tolerate short-term high alkalinity (pH greater than 11), but high alkalinity for a long time will cause the viscosity to decrease; Heat resistance: Sodium alginate can withstand short-term high-temperature sterilization, but long-term high temperature will cause its viscosity to decrease; Compatibility: Sodium alginate can be mixed with most Additive molecules are compatible (except for positively charged molecules). Sodium alginate is more stable in dry powder state than in solution state.

Gel properties

When the pH is lowered, alginic acid will form a gel. The gel strength of this gel is weak, the gel formed is soft, and it is soluble in the alkaline solution; when a small amount of Ca2+ is added to the solution, Ca2+ replaces the alginate. Part of the H+ and Na+ in the gel forms a calcium alginate gel. The gel formed by calcium alginate is thermally irreversible. This is an obvious advantage of sodium alginate over other colloids.

Film forming property

Sodium alginate is a chain-like polymer compound with the ability to form fibers and films.

Chelation

As a chelating agent, sodium alginate can complex divalent ions in the system, making sodium alginate stable in the system. As a chelating agent, chelating sodium alginate can complex divalent ions in the system, making sodium alginate stable in the system.

Antiviral activity of sodium alginate

1. Sodium alginate has good wound protection and wound healing effects. Sodium alginate has excellent antiviral ability.

2. Due to its special growth environment, marine algae have unique biological activities, such as antioxidant, immune regulation, anti-tumor, anti-virus, anti-coagulation, etc.

3. Seaweed polysaccharide (sodium alginate linear polysaccharide), as an acidic polysaccharide, has a wide range of antiviral effects.

Sodium alginate anti-HPV mechanism

Sodium alginate, a type of alginate, has a clear anti-HPV mechanism.

•HPV has a spherical shell-like structure, and its capsid protein is mainly composed of L1 and L2 regions;

•The C-terminus of L1 carries a large number of positive charges and can bind to the negative charges of host cell surface receptors;

•There is also a region rich in positively charged amino acids at the N-terminus of the L2 peptide;

•The positive charges on the surface of L1 and L2 proteins are involved in recognizing negatively charged receptors on the cell surface and producing specific binding during HPV infection.

Advantages of sodium alginate

1. Clear anti-HPV mechanism

The anions carried on the surface of sodium alginate can bind to the positively charged region of the HPV capsid protein, blocking the virus from invading host cells in the basal layer of the vaginal mucosa, thereby blocking HPV infection.

2. Promote wound healing

①Absorb wound exudate and speed up wound healing;

② It can allow oxygen to pass through well and provide an oxygenated environment for wound healing.

Isolate and protect the wound

③ Form a gel protective film on the wound surface to effectively isolate the invasion of external bacteria and viruses.

3. Good biocompatibility

①Natural polysaccharides have good biocompatibility, degradability, and are friendly to mucous membranes without irritation;

② Quickly stop bleeding and relieve pain.

 Test report on Sodium alginate Powder