NMN Powder
Cas No.:1094-61-7
Solubility: Soluble in water
No Irradiation, Non-GMO, Non-Allergen
Comply with Europe standard of PAH4,Benzoapyrene ≤10 ppb
Molecular Formular: C11H16N2O8P
Molecular weight: 334.22
Storage conditions: This product should be sealed and shaded, stored in a dry
Certifications:ISO9001,ISO22000,Kosher,Halal,HACCP
Shipping speed:1-3 days
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Product Introduction
What is NMN Powder?
NMN (Nicotinamide Mononucleotide, referred to as NMN) is a naturally occurring substance in the human body. At the molecular level, it is a ribonucleotide, the basic structural unit of the genetic material RNA; structurally, it is composed of nicotinamide group, ribose and phosphate group. NMN is converted into NAD+ (Nicotinamide Adenine Dinucleotide (nicotinamide adenine dinucleotide) functions.
The full Chinese name of NMN is nicotinamide mononucleotide, which is a naturally occurring substance in the human body and participates in the synthesis of NAD+ in cells. NAD+ is the most important coenzyme in the human body. It participates in thousands of biocatalytic reactions in the human body and is an essential substance for the human body.
NMN, full name: β-nicotinamide mononucleotide, alias: nicotinamide mononucleotide, with a pH value of 3.0-4.0, is a naturally occurring biologically active nucleotide that exists in various organisms. Cosmetic raw materials, white to slightly yellow in color, are crystalline powders with no obvious odor. They need to be stored dry and protected from light at room temperature. The use period is 24 months. The chemical formula is C11H15N2O8P. It is a key intermediate for the synthesis of Coenzyme I - NAD+.
The main functions of NMN
NMN helps delay aging
NAD+ (Coenzyme I) maintains the chemical communication between the nucleus and mitochondria. If this communication is weakened, it will lead to mitochondrial decline. The decline of mitochondria is an important cause of cell aging. NAD+ (Coenzyme I) can maintain the normal expression of genes and maintain cells. Its full-time function slows down the process of cells evolving into senescent cells.
NMN helps prevent three highs and diabetes
The key to lowering blood sugar is insulin. If the pancreatic islet cells are destroyed and cause insulin secretion disorder, it will easily lead to diabetes. NMN can stimulate insulin activity and strengthen the decomposition of fat and polysaccharides, so Nicotinamide Mononucleotide can reduce the risk of diabetes.
NMN helps prevent cardiovascular and cerebrovascular diseases
Clinical studies on arteriosclerosis and related cardiovascular diseases have shown that the oxidation of low-density lipoprotein is an important cause of arteriosclerosis. NMN mainly works by: increasing high-density lipoprotein, reducing low-density lipoprotein, being oxidized, reducing the inflammatory response of macrophages, reducing the formation of atherosclerotic plaques, increasing the stability of atherosclerotic plaques, and reducing plaques. rupture, improve blood flow and other methods mentioned above to prevent and treat cardiovascular disease.
NMN helps boost immunity
NMN can promote the production of antibodies by spleen cells, enhance the function of immune T cells, stimulate the production of immunoglobulins in the body, and has an important immune regulatory effect.
NMN helps prevent high blood pressure
Nicotinamide Mononucleotide mainly inhibits and reverses atherosclerosis by supplementing NAD, allowing foam cells to gradually restore the smooth muscle cells of blood vessels, thereby restoring blood vessel elasticity. At the same time, it prevents the re-formation of thrombus through anti-inflammatory effects, and then opens the blocked collateral circulation and expands it. blood volume, thereby slowly and continuously lowering blood pressure.
Maintain capillary regeneration ability
Muscle cells release growth factors during exercise, and capillary epidermal cells receive growth factors to accelerate growth. This process depends on the longevity protein Sirtuin1 produced by NAD+ (Coenzyme I). The older the person, the less NAD+ (Coenzyme I), and exercise The effect of stimulating muscle growth will be worse.
alcohol metabolism
Alcohol metabolism is divided into two steps. First, it is converted into toxic acetaldehyde, and then further decomposed into harmless acetic acid. Each step must rely on the catalysis of coenzyme I.
NMN helps protect vision
The human retinoid and central nervous system are rich in unsaturated fatty acids. Therefore, free radicals generated by oxidation can easily cause peroxidative damage. Research has found that NMN easily passes through the blood-brain barrier and cell membrane, can effectively prevent retinal oxidation, and plays a protective role in the central nervous system, especially the brain, thereby effectively treating central nervous system injuries such as spinal cord injury, Parkinson's syndrome, Alzheimer's syndrome, etc. damage. In particular, the effect on macular degeneration is more significant than that of lutein.
improve sleeping
Supplementing NMN can increase the level of NAD+ in the body, and NAD+ is also closely related to the biological clock. The interaction between NAD+ and the biological clock is reflected in the fact that the metabolism of NAD+ is regulated by the biological clock, which in turn also affects the biological clock. For people with insufficient sleep and irregular work and rest, increasing the NAD+ level in the body can help regulate the biological clock and restore it to a normal circadian rhythm.
Significantly improve mitochondrial function
Mitochondria are the main "energy powerhouses" in cells, and most metabolic activities in cells require the use of energy stored in ATP. Mitochondria can store energy from food in ATP for subsequent use by metabolic activities. Supplementing NMN can increase the activity of NAD+-dependent Sirts enzymes, remove excessive acetylation modifications of mitochondrial proteins, regulate the activity of downstream metabolic enzymes, greatly improve the ability of mitochondria to provide energy, "nourish" a variety of tissues and organs, and resist aging.
Applicable people for Nicotinamide Mononucleotide
1. Elderly people: used to assist in improving various elderly diseases;
2. Middle-aged people: Eliminate or alleviate various sub-health problems, such as chronic fatigue, poor sleep, vision loss, etc.;
3. Those who stay up late: speed up body recovery;
4. Exam candidates: Improve stress resistance and keep a clear mind;
5. People with higher radiation doses: such as radiologists, nurses, and air crews, to improve their ability to repair genes damaged by radiation;
6. Cancer patients: Help patients after radiotherapy and chemotherapy to repair genes, improve immunity, and speed up physical recovery;
7. Bodybuilders: accelerate muscle growth;
8. Athletes: Improve energy levels and reaction speed;
9. Drinkers: Improve hangover ability, protect the liver, and repair genes damaged by alcohol toxicity;
10. Smokers: Reduce cravings;
11. Depressed people: Increase dopamine levels, improve mood, increase blood supply to the brain, and alleviate brain decline caused by depression;
Can NMN really fight aging?
In 2013, the research team of Professor David Sinclair of Harvard Medical School discovered that NMN can extend the lifespan of mice, triggering an upsurge in NMN research. So far, hundreds of NMN research papers have been published in international academic journals, confirming that NMN can delay aging and prevent and delay a variety of age-related diseases: it helps delay the aging of organs such as the heart, liver, kidneys, and lungs, Improve female ovarian aging and male spermatogenic function, delay the aging of the brain and nervous system, improve intestinal flora, hyperglycemia and cardiovascular problems, help weight management, improve reproductive aging, etc.
NMN’s effect on physiological functions
01 Female:
Mitochondrial function in aged mice also improved significantly after NMN supplementation. Before treatment, more than 40 percent of old oocytes had misaligned mitochondria, impairing their function. After NMN treatment, the proportion of misplaced mitochondria decreased to 24%, which was consistent with increased mitochondrial function.
Together with these beneficial effects on mitochondria, NMN improves ATP (energy) production and mitigates the accumulation of inflammatory reactive oxygen species in aging oocytes. Excessive accumulation causes oxidative stress and DNA damage, potentially leading to cell death (in this case, oocytes), which adversely affects several processes involved in fertilization and pregnancy.
02 Male:
It is an NAD+-dependent deacetylase and is known as an important regulator of aging and longevity. Increased SIRT1 in the brain has been reported to delay aging and extend lifespan in male and female mice +18 and W+NMN restore aging-triggered SIRT1 inactivation Complex dysfunction in the mitochondrial electron transport chain leads to NAD accumulation and NAD deficiency: Subsequent inactivation of mitochondrial SIRT3 leads to severe cardiac damage. This also restores normal levels in men by supplementing W+NMN.
Test report about NMN Powder
ITEM | STANDARD | TEST RESULT |
Assay | ≥99.0% | 99.9% by HPLC |
Physical & Chemical Appearance |
White powder |
White powder |
PH | 2.0-4.0 | 3.13 |
Sodium | ≤1.0% | 0.26% |
Loss on Drying | ≤5.0% | 3.50% |
Heavy Metal Total Heavy Metals |
≤10ppm |
Complies |
As | ≤0.5ppm | Complies |
Pb | ≤0.5ppm | Complies |
Microbiological Test Total Plate Count |
≤1,000cfu/g |
<62cfu/g |
Mold and Yeast | ≤100cfu/g | <10cfu/g |
E.Coli | Negative | Negative |
Salmonella | Negative | Negative |
Certificates
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