D-Mannitol Powder

What is D-Mannitol Powder?

D Mannitol is a natural six-carbon sugar alcohol that was first discovered in pumpkins, mushrooms, onions and seaweed. In 1806, Proust first successfully isolated it from the manna tree, from which mannitol got its name. YTBIO D-Mannitol is a six-carbon linear polyol, white powder crystal, with a molecular formula of C6H14O6 and a molecular weight of 182.17. Mannitol is widely found in algae, fruits, plant leaves and plants, and is also found in small amounts in almost all vegetables.

D-mannitol powder was originally used as a sweetener and diluent, but it was later discovered that it also had diuretic and dehydrating effects and was used in the pharmaceutical field. The pharmacological effects of mannitol are mainly by increasing plasma osmotic pressure, transferring water from tissue fluid to plasma, thereby increasing glomerular filtration rate and urine output, excreting electrolytes such as sodium and potassium, thereby reducing tissue edema.

At present, the most commonly used method for industrial production of D-mannitol powder is chemical synthesis. It mainly uses fructose/glucose mixture as substrate, and obtains mannitol through nickel-catalyzed hydrogenation of fructose/glucose mixture under high temperature and high pressure.

YTBIO supplies 99% D mannitol powder in bulk, with high purity, stable properties and fine powder. YTBIO has passed Halal, Kosher, FDA, ISO and other certifications. We have an excellent R&D team, an experienced production team, and professional sales team. We can customize a variety of standard extracts and proportional extracts. We can provide authoritative third-party testing reports.

Benefits:

Antihypertensive

Mannitol on ocular tissues, by maintaining a high plasma-atrial fluid osmotic pressure difference, induces a shift of atrial fluid into the vasculature. At the same time, the vitreous body dehydrates and decreases in volume. The result is a simultaneous reduction in intravitreal pressure, intraocular pressure, and intraorbital pressure, presenting a powerful hypotensive effect.

Diuretic

The diuretic effect of D Mannitol Powder also contributes to the above effects. Under the influence of mannitol, a large amount of hypotonic urine can be discharged, the plasma is more concentrated, and the osmotic pressure difference is further increased, thus enhancing the antihypertensive effect of mannitol.

Anti-inflammatory, Soothing

D Mannitol Powder can help soothe sensitive skin by reducing inflammatory skin reactions, redness, and irritation. It is also used to soothe discomfort caused by allergies or skin problems.

Moisturising and Nourishing

Because mannitol contains more hydroxyl groups, can be combined with water in the form of hydrogen bonding, moisturizing effect, so it is often added to some skin care products.

Anti-aging

Peroxynitrite anion is a combination of superoxide radicals and nitroso ions, but also a common free radical in the body, this free radical is associated with pigmentation. D Mannitol Powder is conducive to skin conditioning and K decline, skin allergies also have a certain degree of inhibition.

What are the market applications of D-Mannitol?

In Cosmetics:

D Mannitol powder in cosmetics, and skin care products, the main role of adhesives, and moisturizing agents. Risk factor of 1, relatively safe, can be used with confidence, for pregnant women generally has no effect, and D mannitol is not acne-causing. Peroxynitrite anion is a combination of superoxide radicals and nitroso ions but is also a common free radical in vivo, these free radicals and pigmentation related to the elimination of Mannitol are conducive to skin conditioning and anti-aging, skin allergies also have a certain degree of inhibition. D Mannitol powder can inhibit light damage to the skin and photo-aging and has a moisturizing function.

As a Medicinal Excipient:

D Mannitol powder has stable chemical properties, absorbs heat when dissolved, has a sweet taste, and is comfortable for the oral cavity. Therefore, it is widely used in the manufacturing of chewing tablets such as sobering pills, oral cooling agents, and nitroglycerin tablets. Its granular form is specifically used as an excipient for direct tablet compression.

In the Food Field:

Mannitol is internationally recognized as safe for use in food. The U.S. FDA Food Additive Regulation (21st Edition 180.25) approves mannitol for use in food. The Joint Food and Agriculture Organisation/World Health Organisation Committee for the Export of Food Additives (JECFA) has also verified the safety of mannitol and has agreed that it can be taken in a single dose of 0-50mg/kg.

Mannitol is listed in the U.S. Pharmacopoeia/Natural Medicines Chapter, as well as in pharmacopeias around the world, including the Food Chemistry Handbook (FCC). In the Chinese Standard for the Use of Food Additives (GB2760), D Mannitol Powder can be used in confectionery, added as a sweetener, emulsifier, bulking agent, stabilizer, or thickener as required by production.

Other Fields:

Mannitol is a typical polyol whose hydroxyl group can participate in many chemical reactions under certain conditions. Therefore it is often used as an important intermediate in the synthesis of many organic chemicals. For example, in fine chemicals, mannitol can be used to produce polyethers, which are used in the manufacture of high-temperature resistant foams for thermal insulation and fire protection. Mannitol polyether foam is of excellent quality and can withstand temperatures up to 180°C, which is incomparable to polyether foams produced by other polyols, and can be used for insulation of special pipelines.

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