Canthaxanthin Powder

What is canthaxanthin?

Canthaxanthin powder is a natural pigment with great potential as an antioxidant. It has the ability to quench reactive oxygen species and scavenge free radicals. Its ability to quench reactive oxygen species and scavenge free radicals is second only to astaxanthin and is β- It contains nearly twice as much carotene and fifty times as much vitamin E, also known as super vitamin E. In 1984, the FDA/WHO approved canthaxanthin to be listed as a food additive and established quality standards. Canthaxanthin has been widely used as a colorant, nutrient and antioxidant and added to food, feed and cosmetics. Natural canthaxanthin is found in some mushrooms, crustaceans, fish, algae, eggs, blood and liver in very small amounts. In addition, some microorganisms can also produce canthaxanthin.

Cantharidin, also known as β-carotene-4,4'-dione, etc., is one of the five main carotenoids. The vegetables, fruits and beans we usually eat contain this substance to varying degrees. Yellow has antioxidant effects similar to other carotenoid compounds, and also has good coloring ability. It has been widely used in the fields of food, nutrition, cosmetics and feed additives, and plays a huge role.

What are the benefits?

Canthaxanthin is a non-vitamin A source carotenoid. Its chemical structure is composed of 4 isoprene units connected by conjugated double bonds, and there are 2 isoprene units at both ends to form a six-membered ring structure. The C4 and C4' positions of the ring structure contain an oxygen functional group ketone group. In addition to being used as a pigment in animal coloring and cosmetics, canthaxanthin has a variety of physiological functions in animals.

Anti-oxidation

Canthaxanthin powder is an excellent photoprotectant and antioxidant. A large number of clinical trials have shown that the combination of canthaxanthin and β-carotene is much better than β-carotene alone in the treatment of patients with hemorrhagic protoporphyrin (EPP) and complex light disease (PMLE). The intake of cantharides can enhance the activities of glutathione peroxidase, catalase, superoxide dismutase, etc., effectively regulate the balance of the oxidation-antioxidation system in the organism, thereby inhibiting cholesterol-induced oxidative stress.

Improve immunity

Has immunomodulatory activity and acts as an immunomodulatory compound in the human body. Canthaxanthin improves the body's immunity by improving the phagocytic capacity of macrophages, promoting lymphocyte transformation, increasing the number of lymphocytes, and enhancing the activity of natural killer cells.

Protect skin health

Excessive exposure of unprotected skin to the sun can lead to sunburn, which can lead to light-induced oxidation, inflammation, immune suppression, aging, and even cancer of skin cells. Preclinical studies show that typical dietary antioxidants can reduce these injuries. Canthaxanthin has good curative effect on congenital photodermatoses, especially polymorphic light eruption. It also blocks light-induced skin cancer and UV-induced immune suppression.

Protect bone health

It can effectively defend and reduce oxidative damage to osteoblasts, and then protect osteoblast proliferation by quenching free radicals and promote the bone formation process. Studies have found that canthaxanthin can effectively enhance osteoblast proliferation and alleviate differentiation, indicating that canthaxanthin can It may be involved in regulatory activities related to bone metabolism. Coupled with its strong antioxidant capacity, it may have certain preventive or auxiliary treatment significance for aging osteoporosis.

Advantage

Canthaxanthin is a coloring agent. It has many advantages. First, the color tone after coloring is not affected by the pH value. It is also quite stable to sunlight and does not fade easily. Secondly, it can change the skin, fat, etc. of poultry. It is a chemically synthesized pigment. The active ingredient is canthaxanthin. It is mainly added to poultry feed to increase the color and brightness of skin, feet, ketone bodies and eggs. Thirdly, canthaxanthin can also be used as an antioxidant to protect cells in animals from the harm of free radiation.

Physiological metabolic pathways

The biosynthetic pathway of carotenoids such as cantharidin is mainly through the isoprenoid pathway or a branch of the terpenoid pathway, which synthesizes carotenoids such as cantharides from acetyl-CoA via mevalonic acid (MVA). Among them, GGDP (geranylgeranyldiphosphate) is the key intermediate in the entire synthesis system. The specific synthesis route is shown in the figure below:

Bioextraction and chemical synthesis pathways

There are two ways to obtain canthaxanthin: biological extraction and chemical synthesis. Currently, chemical synthesis is the main method. Cantharidin exists in a large number of animals, plants and microorganisms, and natural cantharidin can be obtained through certain extraction methods. The history of chemical synthesis has been more than half a century, and its synthetic routes have been improved and optimized many times, ranging from complex synthesis of cantharidin using C5 compounds as raw materials to simple synthesis of cantharidin using β-carotene as raw materials. route.

Usage limit

FAO/WHO (1984, mg/kg): edible oils and fats according to GMP; canned shrimps, lobsters and quick-frozen products, broths and soups, 30; jams and jelly 200; cold drinks 100. FDA, §73.75(2000): Chemicalbook30mg/456g various foods. Japanese regulations: the addition amount in orange juice drinks is 1~5g/1000L; in ice cream, 10~30mg/kg; tomato soup ≥6mg/kg; tomato paste 1mg/1.5g tomato solids.

Canthaxanthin supplier

Yuantai Organic Bio is committed to providing customers with the highest-quality bulk Canthaxanthin Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

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