Bulk L-leucine Powder

What is leucine?

Bulk L-leucine Powder, whose chemical name is 2-amino-4-methylpentanoic acid, is an organic compound with the chemical formula C6H13NO2. It has three isomers: left-handed, right-handed and racemic. It is a branched-chain amino acid that can Effectively prevents muscle loss because it is broken down into glucose faster.

As the most important member of branched-chain amino acids, leucine is directly involved in the production of skeletal muscle proteins. Leucine initiates the process of muscle growth by activating mTor (target of rapamycin) channels. At the same time, during a calorie deficit (fat loss period), taking sufficient amounts of leucine can maintain net muscle mass, prevent muscle loss, and improve body repair and exercise endurance.

Pure leucine powder was first isolated from cheese by Proust in 1819. Later, Braconnot obtained its crystal from the acid hydrolyzate of muscle and wool and named it leucine. The chemical name of L-leucine is aminoisocaproic acid, and its molecular formula is C6H13O2N. Adding excess leucine to protein-deficient diets can cause growth inhibition, reduce isoleucine and valine levels in blood and organ metabolic pools, and also reduce corresponding ketoacid levels, such as KMV and KIV. Changes in the levels of isoleucine and valine with the mass concentration of leucine can be observed 10 to 30 minutes after leucine enters the stomach. Adding isoleucine and valine to excess leucine diets can partially improve growth inhibition, and adding phenylalanine, tryptophan, and threonine can restore normal growth levels, indicating that low-protein diets can Excess leucine increases the requirements for isoleucine, valine, and other amino acids. During the above-mentioned test, the animals experienced a decrease in feed intake, and 70% of the growth inhibition was caused by the decrease in feed intake. Feed intake did not decrease after oral administration of leucine for 1 to 3 hours.

What are the benefits?

1. Oxidation energy supply

Leucine can be used for protein synthesis in the body, but it can also be used as an energy source during special physiological periods (hunger, lactation, stress and exercise, etc.). When piglets are hungry, the amount of leucine oxidized in their brains and muscles increases. Ruminal protozoa can also use BCAA as an energy source. BCAA can be transaminated and completely oxidized at a faster rate. The efficiency of oxidation to produce adenosine triphosphate (ATP) is higher than that of other amino acids. The complete oxidation of each molecule of leucine, isoleucine and valine produces 42, 43 and 32 molecules respectively. ATP. Its main metabolic site is in muscle. Under the action of transaminases, BCAA transfers the amino group to ketoglutarate to generate glutamate, and glutamic acid transfers the amino group to pyruvate to generate alanine. Under special conditions, the utilization rate of the two gluconeogenic amino acids is increased, and the energy conversion of hepatic gluconeogenesis is accelerated, which reduces the serum alanine and glutamic acid mass concentrations. BCAA supplementation can save muscle glycogen.

2. Regulate protein metabolism

Bulk L-leucine Powder can be used for protein synthesis in the body, but it can also be used as an energy source during special physiological periods (hunger, lactation, stress and exercise, etc.). When piglets are hungry, the amount of leucine oxidized in their brains and muscles increases. Ruminal protozoa can also use BCAA as an energy source. BCAA can be transaminated and completely oxidized at a faster rate. The efficiency of oxidation to produce adenosine triphosphate (ATP) is higher than that of other amino acids. The complete oxidation of each molecule of leucine, isoleucine and valine produces 42, 43 and 32 molecules respectively. ATP. Its main metabolic site is in muscle. Under the action of transaminases, BCAA transfers the amino group to ketoglutarate to generate glutamate, and glutamic acid transfers the amino group to pyruvate to generate alanine. Under special conditions, the utilization rate of the two gluconeogenic amino acids is increased, and the energy conversion of hepatic gluconeogenesis is accelerated, which reduces the serum alanine and glutamic acid mass concentrations. BCAA supplementation can save muscle glycogen.

3. Regulate the body’s immune function

Pure leucine powder deficiency causes thymus and spleen atrophy, lymphoid tissue damage, and reduced immunoglobulin, complement C3, and ferroportin levels in animals. BCAA deficiency in weaned piglets results in a reduced ability to synthesize specific antibodies. Adding rumen protective α-KIC (0.05%) can enhance the antibody response and lymphocyte proliferation response of lambs against pig red blood cells, while adding 0.05% leucine can inhibit the production of antibodies against pig red blood cells; adding leucine to sheep feeding With α-KIC, it can regulate the immune function of its T-lymphocyte subsets. Broiler chickens supplemented with 0.6% α-KIC did not enhance their antibody response against Newcastle disease virus. The effect of leucine and its transamination products on the immune response of animals is affected by factors such as the form, quantity, and type of animal added.

Application direction

Bulk L-leucine Powder can be used as a nutritional supplement, flavoring and flavoring agent, and can also be used to prepare amino acid infusions and comprehensive amino acid preparations, hypoglycemic agents, and plant growth promoters.

Leucine's functions include working with isoleucine and valine to repair muscles, control blood sugar, and provide energy to body tissues. It also increases the production of growth hormone and helps burn visceral fat, which is difficult to effectively target through diet and exercise alone due to its location within the body.

Leucine, isoleucine, and valine are all branched-chain amino acids that help promote muscle recovery after training. Among them, leucine is the most effective branched-chain amino acid, which can effectively prevent muscle loss because it can be broken down and converted into glucose faster. Increasing glucose prevents damage to muscle tissue, so it is especially suitable for bodybuilders. Leucine also promotes the healing of bones, skin, and damaged muscle tissue, and doctors often recommend that patients take leucine supplements after surgery.

Because it is easily converted into glucose, leucine helps regulate blood sugar levels. People with leucine deficiency may experience symptoms similar to those of hypoglycemia, such as headaches, dizziness, fatigue, depression, confusion, and irritability.

The best food sources of leucine include brown rice, beans, meat, nuts, soy flour, and whole grains. Since it is an essential amino acid, this means that the body cannot produce it on its own and can only obtain it through diet. People who engage in high-intensity physical activity and eat a low-protein diet should consider taking a leucine supplement. Although there are stand-alone supplement forms, it’s best to take them together with isoleucine and valine. Therefore, it is more convenient to choose a hybrid supplement.

L-leucine supplier

Yuantai Organic Bio is committed to providing customers with the highest-quality Bulk L-leucine Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

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