What is silymarin powder?

What is silymarin powder?

Silymarin is a natural flavonolignan compound, a natural active substance extracted from the dried fruit of the Asteraceae plant, Silybum marianum. It is insoluble in water, soluble in acetone, ethyl acetate, methanol and ethanol, and slightly soluble in chloroform. Its main components are silybin, isosilybin, silybin and silybin.

It is an antioxidant extracted from a plant called milk thistle. It can stabilize the liver cell membrane and maintain its integrity. It works by promoting the ultrastructure recovery of liver cells, the division and growth of normal liver cells, making it impossible for toxins to penetrate and damage the liver, and can accelerate the synthesis of liver cell DNA.

The liver protection mechanism of silymarin

Antioxidation

It can play the role of an antioxidant by removing reactive oxygen species such as hydroxyl free radicals, thereby maintaining the fluidity of the cell membrane, that is, protecting the liver cell membrane. It inhibits ROS production by inhibiting mitochondrial ROS production, inhibiting ROS synthase expression, and inhibiting Fenton reaction. It also improves antioxidant properties by enhancing the expression of antioxidant enzymes, improving lipid peroxidation, and inhibiting lipid deposition.

Increasing glutathione content

It can increase glutathione synthesis in the liver, stomach, and intestines by increasing cysteine ​​levels, which helps to increase the liver's antioxidant capacity and detoxification level.

Protecting liver cells

It has a significant protective effect on liver cells and can effectively reduce the damage of toxic substances to liver cells. Studies have shown that it can bind to the cell membrane of liver cells, maintain the fluidity of the cell membrane through anti-lipid peroxidation reactions, reduce the attack of toxic substances on the liver cell membrane, and interrupt its transmembrane transport and intercellular transmission, thereby effectively enhancing the resistance of liver cells to a variety of toxic substances and effectively protecting the integrity of liver cells.

Improve liver function

In addition to protecting liver cells, it can also help us prevent liver damage in daily life and reduce the damage to the liver caused by bad habits such as staying up late and drinking in daily life.

Promote the repair and regeneration of liver cells

It can effectively promote the repair and regeneration of liver cells, thereby restoring the normal function of the liver. Studies have shown that it can bind to the estradiol receptors on the surface of liver cells, activate the estradiol receptors, thereby enhancing the activity of RNA polymerase I in the nucleus of liver cells, promote the synthesis of various substances such as DNA and RNA in liver cells, and promote the synthesis of various biological enzymes and structural proteins in cells, thereby effectively promoting the regeneration and repair of liver cells, so that damaged liver cells can restore normal function.

Anti-liver fibrosis

It has obvious anti-liver fibrosis effects, can effectively inhibit liver cirrhosis, and preserve the normal function of the liver. Studies have shown that it has obvious anti-inflammatory and antioxidant activity, which can effectively regulate the synthesis and degradation of extracellular matrix components, inhibit the activation of inflammatory factors for fibrosis programs, thereby reducing the conversion of fibrinogen to fibrin, reducing liver fibrosis, and preserving the normal structure and function of the liver.

Inhibits lipid peroxidation

It can inhibit lipid peroxidation in liver peroxisomes and hepatocytes, and produce a transient inhibitory effect on fatty acid synthesis in the liver.

Application fields

Health care products

It is also widely used in the field of health care products, mainly for health functions such as anti-oxidation, anti-inflammatory, and hypolipidemic. It can help remove free radicals in the body, slow down cell damage, protect the liver, lower blood lipid levels, and delay skin aging.

Cosmetics

The application in cosmetics is mainly to utilize its antioxidant and anti-photoaging properties. Studies have shown that it can inhibit free radicals from damaging cell membranes and prevent lipid peroxidation, thereby protecting the skin from damage by ultraviolet rays and other environmental factors. In addition, it can promote the activity of fibroblasts and epidermal keratinocytes, stimulate the production of elastin and collagen, help the skin maintain elasticity, and reduce the formation of wrinkles and spots. Therefore, this ingredient is added to many high-end skin care products to meet consumers' needs for skin beauty and anti-aging.

Food field

It can be added to food as a functional additive to enhance the nutritional value and health function of food. For example, in the fields of beverages, functional beverages, and infant formula, it not only improves the quality of the product, but also meets consumers' demand for healthy food.

Medical field

‌Fatty liver‌: By improving the energy and material metabolism in liver cells, improving the decomposition of lipid substances by liver cells, reducing the chronic inflammatory response caused by fat accumulation, and protecting the normal structure of the liver‌.

‌Alcoholic liver‌: It can effectively reduce the toxic effects of alcohol on liver cells, protect the integrity of liver cells, and protect and restore liver function‌.

‌Viral hepatitis‌: On the basis of antiviral treatment, it can effectively alleviate the destruction and apoptosis of liver cells, protect liver function, and alleviate patient symptoms‌.

‌Drug-induced liver injury‌: It can reduce the toxic effects of various drugs on the liver and protect liver function‌.

Effects in cosmetics

Antioxidant

It has strong antioxidant effects, can resist free radical damage, slow down the aging of the skin, delay skin aging, and provide comprehensive protection for the skin.

Whitening and brightening

It has the effect of whitening and brightening, can inhibit the production of melanin, improve uneven skin tone, and make the skin more transparent and bright.

Regulate skin metabolism

It has the effect of regulating skin metabolism, can promote cell regeneration, improve skin texture, and make the skin more delicate and smooth.

Anti-inflammatory and calming

It also has anti-inflammatory and calming effects, can relieve skin sensitivity and inflammation, reduce skin discomfort, and make the skin appear healthy.

Removing toxins

It has the effect of removing toxins, can help the skin detoxify, purify the skin, and promote skin health.

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