What Is Nuciferine?

What Is Nuciferine?

Nuciferine is a special alkaline substance extracted from natural lotus leaves. It is the main lipid-lowering active ingredient in lotus leaves. The extraction process of Nuciferine includes a series of methods such as pretreatment of dried and crushed lotus leaf raw materials, dilute hydrochloric acid extraction, ultrasonic assisted extraction, chloroform extraction, etc. In addition to its medical and dietary effects such as lowering blood lipids, resisting free radicals, inhibiting hypercholesterolemia and arteriosclerosis, Nuciferine also has anti-mitotic effects and has a strong antibacterial effect.

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What Are The Benefits Of Nuciferine For Health?

Antioxidant

The scavenging effect of lotus leaf extract on free radicals was determined by chemiluminescence. The results showed that lotus leaf is an effective free radical scavenger. Lotus leaf extract has strong antioxidant activity and the ability to protect cells from oxidative damage.

Clearing away heat and dampness

Nuciferine is a special alkaline substance extracted from natural lotus leaves. It is also a slightly cool medicine that can clear away heat and dampness. It can improve the situation of strong heat toxins or high humidity in the body in daily life.

Nourishing blood and stopping bleeding

Nuciferine can assist in dilating blood vessels in the body. The purity of this alkaloid is also relatively high. It can nourish blood and stop bleeding. It contains certain natural ingredients. It can help regulate anemia and blood deficiency in daily life. At the same time, if there are some symptoms such as bruises, coughing up blood, and bloody stools, taking an appropriate amount of nuciferine can also stop bleeding and control the symptoms.

Assist in reducing blood pressure and lipids

Lotus leaf alkaloids are a special alkaline substance. After taking an appropriate amount, they can reduce the active components of fat. They can also assist in reducing blood pressure for patients with elevated blood lipids and blood pressure in daily life. However, those with more serious diseases need to be treated with targeted drugs.

Weight loss effect

Lotus leaf alkaloids contain a variety of effective lipogenic alkaloids, which can effectively decompose fat in the body and help excrete it from the body. They have significant effects on detoxification and weight loss, and can also help remove free radicals.

Improve diet

Lotus leaf alkaloids have the effects of clearing heart fire and lung fire, and can regulate the body's endocrine system. In addition, it can also improve greasy eating habits and has a strong repulsive effect on oil.

Health care effect

Lotus leaf alkaloids can effectively reduce cell fat in the body and improve the body's ability to treat insulin, thereby preventing the occurrence of high-fat diseases, which is very helpful for obese people.

Antibacterial and antiviral

Lotus leaves contain a lot of alkaline components, such as nelumboine, nelumboine, N-demethylnelumboine, D-N-methylcoclaurine, tomato cladocerine, etc. These alkaline components can inhibit mitosis and have a strong antibacterial effect. In addition, flavonoids, volatile oils, saponins, and glycosides in lotus leaves also have certain antibacterial activity.

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What Are The Benefits Of Nuciferine For Cardiovascular Health?

Preventing atherosclerosis: Nuciferine can effectively prevent atherosclerosis caused by high blood lipid concentration.

Control blood pressure: Nuciferine can dilate blood vessels, clear away heat and relieve summer heat, and has the effect of lowering blood pressure.

Preventing thrombosis and cerebral hemorrhage:It can prevent cardiovascular and cerebrovascular diseases such as thrombosis and cerebral hemorrhage caused by high blood lipid concentration.

Lowering blood lipids and cholesterol: Nuciferine can effectively lower blood lipid and cholesterol levels, and has significant effects on the treatment of cardiovascular diseases such as hyperlipidemia, atherosclerosis, and coronary heart disease.

Preventing and treating cardiovascular diseases: The flavonoids rich in lotus leaves have strong antioxidant properties, which can remove free radicals, reduce the destructive effect of free radicals on blood vessel walls, increase coronary blood flow, eliminate myocardial infarction, and prevent and treat high blood, coronary heart disease, etc.

What Is The Antioxidant Mechanism Of Nuciferine?

Free radical scavenging: Nuciferine can scavenge DPPH free radicals and superoxide anion free radicals, but has a weak scavenging effect on ABTS+·. Studies have shown that the scavenging effect of nephrocithin on free radicals is dose-dependent, and there is a significant synergistic effect with other active ingredients.

Antioxidant activity: Nuciferine exhibits certain antioxidant activity in vivo and in vitro. Studies have shown that nephrocithin can effectively inhibit the absorption of fat by the intestine and promote fat metabolism, thereby regulating lipid metabolism. nephrocithin can also dilate blood vessels, lower blood pressure, protect the heart, etc.

Activation of antioxidant enzymes: Nuciferine inhibits the activity of mTORC1 by targeting HBXIP, thereby activating the TFEB-mediated autophagy-lysosome pathway and alleviating fatty liver. This suggests that nephrocithin may exert its antioxidant effect by activating specific antioxidant enzyme pathways.

Anti-inflammatory effect: Nuciferine and other substances have anti-inflammatory effects, which can effectively inhibit leukotriene-induced rat lung tissue inflammation and reduce inflammatory responses. Nuciferine can also relieve cotton ball granuloma in rabbits and reduce the number of subcutaneous fat cells in rabbits.

In What Fields Can Nuciferine Be Used?

Health care products

Heat-clearing and summer-heat-relieving: Nuciferine have the effect of clearing heat and relieving summer-heat, and are often used in health foods in summer.

Antioxidant and anti-aging: Nuciferine has antioxidant and anti-aging effects, and can be used to make related health products.

Antibacterial effect: The antibacterial effect of lotus leaf alkaloids makes it used in certain health products with antibacterial functions.

Weight loss and lipid reduction: Nuciferine is used in weight loss health products, which can prevent fat synthesis, penetrate the skin, renew cell tissues, promote the discharge of excess water and waste toxic substances in the body, and accelerate the decomposition and metabolism of fat cells.

Cosmetic field

Whitening and anti-aging: Lotus leaf alkaloids are rich in alkaloids, flavonoids, polysaccharides, essential oils and other bioactive ingredients, which help improve skin problems such as red blood streaks, dandruff removal, anti-acne, acne removal, and wound repair.

Oil control and skin conditioning: Nuciferine can effectively decompose body fat and strongly excrete it from the body. When used in cosmetics, it has a strong oil repellent effect, helps inhibit fat absorption, thereby improving greasy eating habits and has a significant effect on reducing skin oil secretion.

Medical field

Treatment of hypertension and hyperlipidemia: High-purity nucifera alkaloids are mainly used for the treatment of hypertension and hyperlipidemia in clinical practice.

Prevention of atherosclerosis: Nuciferine can effectively prevent cardiovascular and cerebrovascular diseases such as thrombosis and cerebral hemorrhage caused by high blood lipid concentrations in patients.

Lowering serum uric acid levels: Nuciferine and their analogs are also used in the preparation of drugs for the treatment or prevention of hyperuricemia.

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