What Is Green Tea Catechin
There are many benefits to drinking green tea. Mainly because it is rich in flavonoids, especially catechins.
Catechins have many pharmacological effects, such as anti-tumor, anti-saccharification, anti-bacteria and protection of heart and brain organs. These pharmacological activities are mainly determined by their polyhydroxy structure. However, the polyhydroxy structure also makes the structure of catechins unstable under neutral and alkaline conditions.Catechins will soon be methylated or glycosidized under the action of biological enzymes after being ingested by the human body. Studies have found that introducing other groups into the structure of catechins can effectively improve its stability and bioavailability, and specifically enhance the pharmacological effects of catechins.Among them, methyl catechin showed outstanding performance in anti-allergy and reversal of drug resistance of tumor cells, glycoside catechin significantly improved water solubility and effectively prevented Browning, while acylated catechin also significantly enhanced its antioxidant and anticancer activities due to its significantly enhanced lipid solubility. The effect of substitution at different locations is also different.
Catechin compounds are the main functional components in tea, accounting for 12%-24% of the dry weight of tea. Catechins in tea plants mainly include, Epicatechin (EC), Gallocatechin (GC), epigallocatechin (EPigallocatechin). Epicatechin gallate (ECG), Gallocatechin gallate (EGC), Catechin gallate (CG), Epicatechin gallate (ECG), Gallocatechin gallate (EGC), Catechin gallate (CG), Epicatechin gallate (ECG) GCG) and epigallocatechin gallate (EGCG). It is widely known that catechins have anti-inflammatory, antibacterial, antiviral and antioxidant functions. Among them, EGCG is the most outstanding antioxidant, and can effectively balance free radicals in human body by removing reactive oxygen species (ROS) and NO or reacting with ROS to generate stable compounds. With the deepening of research on catechins, more pharmacological functions have been discovered. Catechins can inhibit the proliferation of cancer cells and induce the apoptosis of cancer cells by regulating the activity of related enzymes or specifically binding with related enzyme proteins, but there are significant differences among different catechins monomers. Catechins can also prevent cardiovascular and cerebrovascular diseases and protect the kidney, liver and nervous system. The development and application of catechin are greatly restricted by its low lipid solubility, poor stability and low utilization rate in human body. Therefore, researchers hope to improve the efficacy and bioavailability of catechins by enzymatic, chemical and microbial structural modification.
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