What is ginsenosides?

What is ginsenosides?

Ginsenosides are an active ingredient derived from ginseng. They are a steroid compound, a triterpenoid saponin, and a natural ingredient. They are currently one of the commonly used botanical ingredients and are considered to be the active ingredient in ginseng.

Ginsenosides are a group of triterpenoid saponins extracted mainly from Panax ginseng herbs. They are a polysaccharide derivative. Ginsenosides have a wide range of biological functions, such as anti-oxidation, liver protection, blood lipid reduction, and improvement of cardiovascular and cerebrovascular diseases.

What are the benefits of ginsenosides?

Improve cardiovascular and cerebrovascular system

Ginsenosides have a regulatory effect on the "three highs" (high blood pressure, high blood lipids, and high blood sugar), can lower blood lipids, regulate blood pressure, and may lower blood sugar by stimulating the endocrine system. Some ginsenosides such as Rg2 have anti-shock effects, can quickly improve myocardial ischemia and hypoxia, and help prevent and treat coronary heart disease.

Improve immunity

Ginsenosides can enhance the body's immune function and regulate both cellular immunity and humoral immunity, thereby improving the body's resistance and preventing diseases. For example, Rh2 can enhance the activity of immune cells such as macrophages, T lymphocytes, and B lymphocytes.

Antioxidant

As a natural antioxidant ingredient, ginsenosides can remove free radicals in the body and reduce the damage of free radicals to cells. It can also increase skin elasticity, reduce wrinkle formation, and have a certain nourishing effect on the skin.

Delaying aging

Ginsenosides, such as glycine, histidine, and arginine, can help produce collagen in the skin, improve the skin, and provide the nutrients needed for cartilage, once supplemented, and can help remove free radicals and delay aging.

Anti-fatigue

Ginsenosides have the function of regulating nerve excitement and anti-fatigue, and can relieve physical fatigue and mental stress. For example, Rg1 can excite the central nervous system, resist fatigue, and improve memory and learning ability.

Lowering blood pressure and protecting myocardial blood vessels

Ginsenosides have a two-way blood pressure regulation effect, which can help repair damaged vascular smooth muscle endothelium, dilate blood vessels, reduce lipid deposition in vascular parts, and have a good improvement effect on atherosclerosis. It can also improve myocardial blood vessels, lower blood pressure and prevent hypertension.

Sobering up and protecting the liver

Ginsenosides can accelerate alcohol metabolism and promote the body's metabolism, accelerate alcohol excretion and improve liver function, and can improve vomiting, nausea, etc. caused by drunkenness. Better sobering up can also be used to prevent and treat alcoholic liver and help protect the liver.

Replenishing Qi and Blood

Ginsenosides have high nutritional value, can help improve women's reproductive function, and also have good effects of nourishing Yin, nourishing the skin, replenishing blood and replenishing Qi. Taking them can better regulate endocrine disorders and help improve women's Qi and blood deficiency.

Lowering blood lipids

For people with high blood lipids, taking ginsenosides can help improve blood lipid concentration. Ginsenosides can reduce human serum cholesterol and fat deposition. After intake, it can reduce blood lipids, improve the prevention of cardiovascular diseases, and prevent the occurrence of atherosclerosis.

Antioxidant effect of ginsenosides

Ginsenosides are active ingredients in ginseng and have multiple biological activities, including antioxidant effects. According to the latest research, ginsenosides can effectively fight photoaging and have anti-apoptotic effects on the skin. The protective effect of ginsenosides on the skin is reflected in its ability to inhibit cell apoptosis caused by adriamycin damage and to have a certain repair effect on fibroblasts.

In addition, different types of ginsenosides have different effects. For example, ginsenosides Rb1, Rg1, Rh1, Re and other ingredients have been shown to have anti-aging and antioxidant effects. In addition, the antioxidant capacity of ginsenosides is positively correlated with the dose. The higher the concentration, the stronger its antioxidant capacity and the stronger its ability to remove hydroxyl free radicals.

The antioxidant mechanism of ginsenosides is mainly to remove free radicals in the body and prevent the generation of free radicals, thereby protecting cells from damage and effectively delaying various aging of the body. This characteristic makes ginsenosides show potential application value in protecting skin health and reducing wrinkles.

In summary, the antioxidant effect of ginsenosides is mainly reflected in its ability to delay aging, protect skin cells, and slow down cell damage by scavenging free radicals and preventing their generation.

Effects of ginsenosides on the cardiovascular system

Cardioprotective effect: Ginsenosides can improve the contractility of the myocardium. In animal experiments, the effect of ginsenosides on the heart is first excitation and then inhibition, small amounts of excitation and large amounts of inhibition. In addition, ginsenosides have a strong anti-arrhythmic effect, which can correct tachycardia and restore the heart rate to normal levels.

Vascular regulation: Ginseng can act as a vasodilator on blood vessels, but there are also reports of small doses of contraction, large doses of expansion, or contraction first and then expansion. Ginseng has a dilating effect on coronary arteries, cerebral blood vessels, and fundus blood vessels. At the same time, ginsenosides also have the ability to regulate blood pressure, which can both lower high blood pressure and raise low blood pressure.

Blood pressure lowering and blood pressure raising mechanism: In normal or high blood pressure states, ginseng has the effect of lowering blood pressure, and in some cases, ginseng can also increase blood pressure, which may be related to the reduction in the size of the kidneys and spleen and the contraction of visceral blood vessels. The antihypertensive effect may be due to the release of histamine.

Protecting myocardial cells: Saponins extracted from different parts of ginseng have a protective effect on myocardial cells, especially ginsenosides have a significant protective effect on myocardial necrosis caused by isoproterenol.

Improving blood lipids: Ginsenosides inhibit atherosclerosis through their anti-inflammatory effects and improved lipid characteristics, thereby improving lipid distribution in the body.

Anti-platelet aggregation: Ginsenosides can inhibit platelet aggregation and prevent thrombosis, which is of great significance for preventing cardiovascular and cerebrovascular diseases.

Anti-oxidation and improving blood circulation: As an antioxidant, ginsenosides can scavenge free radicals to protect myocardial cells from oxidative damage, and play an antioxidant role during myocardial ischemia, increasing myocardial cell survival and myocardial contraction.

What are the application fields of ginsenosides?

Food and beverage field

Ginsenosides are widely used to make functional foods and beverages, and have many functions such as improving immunity, delaying aging, and protecting the liver.

Health care products field

Ginsenosides are used to make a variety of health care products, including enhancing immunity, regulating blood pressure, and losing weight.

Cosmetics field

Although most cosmetics claiming to have ginseng ingredients contain extremely small amounts of ginsenosides or even none, cosmetics that truly contain ginsenosides have excellent effects in moisturizing, repairing, anti-aging, and whitening.

Medical field

Ginsenosides are used to make anti-inflammatory, antioxidant and other drugs, as well as for the auxiliary treatment of diabetes, hypertension, coronary heart disease and other diseases.

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