What Is Dihydromyricetin Powder Good For?

What Is Dihydromyricetin Powder Good For?

Dihydromyricetin is a flavonoid compound, mostly extracted from a woody vine plant, Agave sphenodonta, of the genus Agave in the grape family. It is widely found in various plants, and Ampelopsis pilosula is the plant with the highest known content. It is highest in the tender stems and leaves of Ampelopsis pilosula, exceeding 35% of the dry weight, and is the main bioactive substance in Ampelopsis pilosula. As a natural flavonoid compound, its molecular structure contains two benzene rings and one pyran ring, forming a complex ring structure, presenting as a white crystalline powder. It has low solubility in water, but is easily soluble in organic solvents such as methanol and ethanol, slightly soluble in acetone and chloroform, and almost insoluble in petroleum ether and benzene.

It is a relatively special flavonoid compound. In addition to the general characteristics of flavonoid compounds, it also has the functions of relieving alcohol poisoning, preventing alcoholic liver, fatty liver, etc. It is a good product for protecting the liver and sobering up.

What are the functions of dihydromyricetin?

Sobering up and protecting the liver

It can significantly increase the activity and concentration of acetaldehyde dehydrogenase, accelerate the decomposition of acetaldehyde, and reduce the damage of alcohol to the liver. At the same time, it can also improve liver cell damage, inhibit liver cell deterioration, and play a role in protecting the liver.

Antioxidant and anti-aging

It has strong antioxidant capacity, can remove free radicals in the body, and reduce the damage caused by free radicals to cells and tissues. By taking food or supplements containing it, you can maintain the health of cells and delay the aging process.

Regulating blood lipids and blood sugar

It can regulate blood lipid and blood sugar levels and prevent cardiovascular diseases. Pharmacological experiments on mice gavage showed that it can significantly inhibit the increase in blood sugar in mice induced by alloxan, adrenaline, etc., and at the same time increase serum insulin levels, which is of great significance for the auxiliary treatment of diabetes.

Anti-fatigue

It can effectively reduce mitochondrial damage induced by hypoxia, and can reduce the activity of blood urea, serum lactate dehydrogenase and creatine kinase. It plays an anti-fatigue role by promoting the biosynthesis of mitochondria in skeletal muscle and regulating the dynamic changes of mitochondrial fission and fusion.

Antibacterial

Experiments have shown that it has antibacterial effects on Bacillus subtilis, Staphylococcus aureus, Salmonella, Escherichia coli, Bacillus aerogenes, Saccharomyces cerevisiae, Rhodotorula glutinosus, Penicillium, Aspergillus niger, Aspergillus flavus, Mucor and Rhizopus, especially on Gram-positive and Gram-negative cocci or bacilli.

Immunity enhancement

It can activate immune cells, promote the production of immune factors, enhance the function of the immune system, and prevent infectious diseases such as colds.

Neuroprotection

It can not only directly participate in the process of synaptic electrical signal transmission in the brain as an inhibitory neurotransmitter receptor function regulator, but also regulate neural function by upregulating the expression of neurotrophic factors, and indirectly repair damaged or aged neural function by affecting cell apoptosis and autophagy pathways, and improve a variety of neuropsychiatric diseases.

Application of dihydromyricetin in liver protection

It not only has a wide range of pharmacological activities, such as free radical scavenging, anti-oxidation, anti-thrombosis, anti-inflammatory and other unique effects, but also has a wide range of liver protection effects, such as improving acute liver damage, alleviating alcoholic and non-alcoholic fatty liver, regulating liver regeneration, and inhibiting liver cell deterioration.

Accelerate acetaldehyde decomposition: It can significantly increase the activity and concentration of acetaldehyde dehydrogenase, accelerate the decomposition of acetaldehyde, and thus reduce alcohol damage to the liver.

Improve liver cell damage: This compound can improve liver cell damage, inhibit liver cell deterioration, and play a role in protecting the liver. This is especially important for people who drink frequently or have poor liver function.

Anti-inflammatory and antioxidant effects: It has anti-inflammatory and antioxidant properties, which helps to reduce the inflammatory response and oxidative stress of the liver and further promote liver health.

Regulate liver regeneration: By activating mechanisms such as Sirtuins and AMPK, dihydromyricetin helps regulate the liver's regeneration process and prevent further damage to liver cells.

In terms of liver protection, studies have found that it improves the mitochondrial respiratory capacity and redox homeostasis of hepatocytes through a SIRT3-dependent mechanism, thereby preventing non-alcoholic fatty liver disease. It can accelerate the rapid decomposition of acetaldehyde, a metabolite of ethanol, into a non-toxic substance, reducing its damage to liver cells. In addition, it can also improve the increase in serum lactate dehydrogenase activity caused by liver cell damage, inhibit the formation of collagen fibers in hepatic M cells, thereby playing a role in protecting the liver, greatly reducing ethanol damage to the liver, and quickly restoring the liver to normal state. It takes effect quickly and has a long-lasting effect. It is a good product for protecting the liver and sobering up from alcohol.

How does DMY sober up?

Acetaldehyde, the metabolite of ethanol, is the main cause of dizziness and hangover after drinking, and the main substance that causes damage to the liver. DMY can protect the liver, accelerate the rapid decomposition of acetaldehyde, the metabolite of ethanol, and reduce its damage to liver cells. In addition, DMY can improve the increase in serum lactate dehydrogenase activity caused by liver cell damage, inhibit the formation of collagen fibers in hepatic M cells, thereby playing a role in protecting the liver and greatly reducing liver damage.

Its magic is that no matter how high the alcohol content in the blood is, it can prevent the brain from feeling the intoxicating effect. DMY can indeed increase the speed at which a person wakes up after drinking.

Reduce the impact of alcohol on the brain

Most common symptoms of alcoholism, such as reduced inhibition, slurred speech, and loss of balance, are caused by the action of GABA receptors in the brain. DMY has the ability to counteract this effect even if the alcohol content in the blood is still high.

Improve liver function

The liver needs enough time to fully process alcohol and excrete it from the system. With the help of DMY, the liver can work faster and the patient can wake up faster.

Extraction method

A method for extracting DMY from rattan tea, specifically comprising the following steps:

(1) soaking the dry leaves of rattan tea in a solvent;

(2) filtering and subjecting the wet rattan tea leaves to microwave radiation;

(3) combining the filtrate with the microwave-irradiated rattan tea leaves, and extracting by heating in a water bath;

(4) filtering while hot, and separating the filtrate by crystallization.

Application areas

Food

It can be used as a food additive to enhance the taste and nutritional value of food. In functional beverages and nutritional supplements, DMY is widely adopted due to its unique biological activity.

Health products

As people's health awareness increases, the application of DMY in the field of health products has gradually attracted attention. To enhance the antioxidant function of the product and help consumers improve their health.

Cosmetics

DMY is also used to develop new cosmetic products, using its antioxidant and anti-inflammatory properties to enhance the health benefits of the product.

Medicine

DMY has shown significant therapeutic effects in the treatment of respiratory infections, alcoholism, etc.

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