Is D-panthenol safe for the skin?

Is D-panthenol safe for the skin?

D-panthenol, also known as calcium pantothenate or provitamin B5, is a water-soluble vitamin that is widely found in many foods in nature, such as whole grains, vegetables and meat. It is converted into coenzyme A in the human body. Coenzyme A is a cofactor in many enzyme reaction pathways in the body. It participates in cellular energy metabolism and provides energy for the body's life activities. In addition, it is also involved in the metabolism of many key components in the skin, which is essential for maintaining skin health.

Its nature is unstable and is easily affected by temperature and formula, which reduces its bioavailability. Therefore, its precursor, panthenol, is often used in cosmetic formulas. Panthenol has good skin absorption characteristics and can be quickly converted to pantothenic acid through oxidation.

In recent years, with the deepening of scientific research, the application of D-panthenol in the field of skin care has increased. Its excellent moisturizing function can attract and lock moisture, helping the skin maintain moisture balance. In addition, D-panthenol can also enhance the skin barrier function and reduce the irritation and damage to the skin by the external environment.

In summary, as a skin care ingredient, D-panthenol has many benefits for skin health due to its moisturizing, repairing and anti-inflammatory properties. Although it may not have received enough attention in the skin care market, with the support of scientific research and the improvement of consumer awareness, D-panthenol is expected to become one of the indispensable ingredients in skin care products.

Skin’s natural protector: D-Panthenol

Hydrate

Its molecular diameter and molecular mass are very small, and it can penetrate deep into the skin barrier and penetrate deep into the stratum corneum of the skin, bringing the moisture into the skin, thereby replenishing and moisturizing it. Some studies have shown that after using a product containing 2.5% D-panthenol for 7 days, and then comparing it with a control product, it was found that the moisture content of the human stratum corneum was significantly improved when using the product containing 2.5% D-panthenol. So its hydrating effect is also very powerful.

Hydrates and repairs barrier

As a small molecule moisturizer, it can increase the hydration of the stratum corneum, reduce transepidermal water loss (TEWL), improve skin barrier function, improve skin roughness and soothe irritated skin, and can also accelerate the effectiveness through hydration reaction Ingredients absorbed.

Anti-inflammatory, soothing and repairing

On the one hand, ubiquinol can protect against stress damage, reduce the production of reactive oxygen species and free radicals in skin cells, and at the same time upregulate the skin's own antioxidant mechanism, including inducing skin cells to express more antioxidant factors - heme oxygenase 1 (HO-1), thereby improving the skin’s antioxidant capacity. On the other hand, panthenol can also effectively inhibit inflammatory reactions, relieve erythema, itching and pain, and reduce skin irritation, thereby achieving a soothing effect.

Adjustment improvement

Research shows that when used together with vitamin B6 and fully absorbed by the skin, it can increase the content of hyaluronic acid in the skin and enhance the body's metabolism of proteins, sugars, fats and other substances. This plays a role in regulating the skin. At the same time, panthenol can also strengthen skin elasticity, improve rough skin, and relieve skin itching, and is very friendly to sensitive skin.

Anti-inflammatory and sedative

It has the effect of stimulating the growth of epithelial cells in the skin, so it can calm and reduce inflammation, promote metabolism, and accelerate wound healing. Therefore, panthenol is generally added to cosmetics and skin care products for acne-prone skin. When its anti-inflammatory and sedative effect is applied to acne-prone skin, it will make the acne disappear faster and the wounds left after popping the acne will heal faster. Therefore, panthenol is a very strong ingredient for acne-prone skin.

Promote wound healing

It can significantly increase the expression of IL-6, IL-8 and other cytokines, thereby activating the proliferation of dermal fibroblasts, accelerating epithelial cell regeneration and helping wound healing.

Is it useful for hair care?

Moisturizing and repairing: It can penetrate deep into the hair, moisturize for a long time, improve hair gloss, reduce split ends, prevent dryness and breakage, and repair damaged hair. After using shampoo or conditioner containing D-panthenol, some sticky and transparent residues can be left on the hair, which can wrap the hair and play a role in shining.

Promoting growth: It helps to promote hair growth and improve the gloss and texture of hair. It stimulates hair growth and increases hair follicle straightness by reducing the expression of cell apoptosis and aging markers, prolonging the growth phase of hair follicles, and promoting the transformation of hair from the resting phase to the growth phase.

Interaction between panthenol and other ingredients

Panthenol can be used together with retinol (vitamin A alcohol)

Retinol itself can promote skin epidermal metabolism and brighten skin tone to a certain extent; panthenol can moisturize and soothe after retinol, and can also relieve the irritation caused by retinol to a certain extent.

Panthenol can be used together with asiaticoside

The combination of panthenol and asiaticoside, both of which have the effect of promoting skin repair, can better promote wound healing and improve skin repair.

Panthenol can be used together with vitamin B6

When panthenol and vitamin B6 are used together, they can increase the content of hyaluronic acid in the skin and promote the metabolism of human protein, sugar and fat.

Application Scope

Cosmetics

As a moisturizing and barrier repairing ingredient, it can improve the hydration of the stratum corneum, reduce transepidermal water loss, improve the skin barrier function, reduce skin inflammation and allergic reactions, and is used in makeup products such as foundation, concealer, and mascara.

Personal Care

In skin care products, such as face creams, body lotions, and hand creams, it provides softness and moisturizing effects, and improves dry, rough, and damaged skin.

In hair care products, such as shampoos, conditioners, and hair masks, it can provide nourishing and repairing effects, and improve the strength, gloss, and softness of hair.

Medicine

As a vitamin B drug, D-panthenol participates in the metabolism of proteins, fats, and sugars in the body, protects the skin and mucous membranes, and improves the gloss of hair. It can also accelerate wound healing and has an anti-inflammatory effect.

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