What is Cnidium monnieri extract? Does it have any benefits?
What does Cnidium monnieri extract do?
Cnidium monnieri extract is a substance extracted from the dried and mature fruits of the plant Cnidium of the Umbelliferae family. Cnidium monnieri, also known as wild carrot seeds, is mainly picked in summer and autumn. It has a mild temperament and a slightly bitter taste. Its fruit contains a variety of active ingredients, including pinene, isovalerate bornyl ester, parsley methyl ether, dihydroparanthol, bergamot lactone, osthole and isoanisolin.
Cnidium monnieri is a common plant that is widely used in traditional medicine and has a variety of medicinal properties. Its main active ingredients are several coumarin compounds, among which osthole has a high content. There may be applications in areas such as herbalism, drug development, or the nutraceutical industry, but specific uses and industry definitions may vary by market and application.
Modern pharmacological research shows that Cnidoma monnieri has significant effects on the cardiovascular system, central nervous system, reproductive system, neuroendocrine system, etc., and has significant effects in antibacterial, antiviral, antimutagenic, and anti-inflammatory aspects.
Is Cnidium monnieri Extract Good for You?
Antibacterial
It has certain antibacterial and antifungal activity, and the alkaloid components it contains can inhibit the growth of a variety of pathogenic microorganisms. Cnidium monnieri coumarin has an inhibitory effect on various bacteria such as Escherichia coli and Candida aureus, which can reduce the pathogenicity of Candida aureus and inhibit the production and spread of bacterial factors.
Anti-inflammatory
Because some compounds in the extract have the effect of inhibiting the activation of inflammatory cells, it can have an anti-inflammatory effect. It has a certain alleviating effect on inflammatory diseases such as skin itching and eczema. It is recommended that patients use it in moderation under the guidance of a doctor.
Antioxidant
It has the ability to scavenge free radicals, so it can play an antioxidant role, help delay aging and protect skin health.
Anti-allergic
Certain substances in Cnidium monnieri extract have the effect of stabilizing mast cell membranes, thereby reducing the release of mediators such as histamine, achieving the purpose of anti-allergy. It is suitable for the treatment of allergic reactions such as urticaria and contact dermatitis. Patients need to take it according to the prescribed dose.
Anti-osteoporosis
Osthole can promote the proliferation and differentiation of bone cells, increase the expression levels of osteocalcin and alkaline phosphatase, promote bone strength, and prevent osteoporosis.
Endocrine regulation
It can regulate the synthesis of androgens in testicular interstitial cells, promote hormone secretion, increase the testosterone content and progesterone content in serum, and can also protect female ovarian tissue, enhance the antioxidant capacity of the ovaries, enhance fertility, and prevent infertility; promote the synthesis and secretion of androgens in testicular interstitial cells.
Anti-arrhythmic
It has a preventive effect on chloroform-induced ventricular fibrillation in mice, calcium chloride-induced ventricular fibrillation in rats, and aconitine-induced arrhythmia in rats, and has a significant therapeutic effect on the latter. This shows that the water extract of Cnidium monnieri has an anti-arrhythmic effect.
Does it have any effect on skin itching?
1. Osthole and the origin of acute itch behavior
The study found that it effectively inhibits the itching caused by substance P. Although chloroform extract contains osthole, osthole cannot inhibit the itching behavior caused by substance P.
Osthole cannot inhibit the itching caused by substance P
Osthole inhibits the itching caused by 48/80
2. Subcutaneous injection of osthole inhibits the itching caused by histamine
Osthole can also inhibit the itching caused by dorsal administration of histamine and histamine receptor H1 receptor and H4 receptor agonists.
Osthole inhibits the itching caused by histamine
Osthole inhibits the itching caused by histamine through TRPV3
3. Osthole can also inhibit the acute itching caused by chloroquine
4. The mechanism of osthole inhibiting acute itching-TRP channel
Inhibit calcium ion influx into dorsal root neurons of the spinal cord
Inhibit TRPV3 current
Which industry markets are used?
Food additives
In the field of food additives, it can be used as a functional additive such as a preservative, pigment, and flavor enhancer. It can effectively extend the shelf life of food and improve the taste and appearance of food.
Cosmetics
It has anti-allergic and anti-allergic effects, has a strong anti-histamine effect, and can be used in anti-allergic cosmetics. It is mainly used in anti-acne and anti-inflammatory cosmetics, and can be added to essences, facial masks, lotions, creams, lotions, skin care gels and other skin care products of various textures.
Medical and health products
It is widely used in medical and health products, mainly for warming the kidney and strengthening yang, drying dampness, dispelling wind, and killing insects. It is often used to treat symptoms such as impotence, cold uterus, cold and dampness, and dampness and back pain. It may also be used to make health products or nutritional supplements to improve health and promote body functions.
Agriculture
In agriculture, it can be used as a plant growth regulator and bactericide. It can promote the growth and development of plants and increase the yield and quality of crops. At the same time, its properties help to control crop diseases and insect pests and reduce the use of chemical pesticides.
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