What does serrapeptase powder do?
2024-12-10 12:21:46
What does serrapeptase powder do?
Serrapeptase, also known as serrapeptase, is a proteolytic enzyme isolated from the intestine of silkworms. It was originally isolated from the intestinal flora of silkworms. This enzyme is produced by Streptomyces mitofus and has a strong ability to decompose proteins. According to published studies, it is classified as a proteolytic enzyme, which means that it can break down proteins into basic components, namely amino acids.
It was discovered in the early days that it has protein dissolving ability and can inhibit inflammatory substances. It is mostly used as an expectorant and pus-removing drug. At the same time, serrapeptase also has the ability to promote cell regeneration and wound healing. When used together with antibiotics, it has a synergistic effect to enhance the antibacterial effect of antibiotics.
What is the anti-inflammatory mechanism of serrapeptase?
Proteolytic activity: It is a proteolytic enzyme that can break down proteins, thereby affecting proteases of inflammation and blood coagulation.
Regulate immune cell migration: It effectively regulates the migration of immune cells from lymph nodes to inflamed and injured tissues, helping tissues to return to normal and maintain homeostasis.
Decomposition of cyclooxygenase: It works in part by breaking down cyclooxygenase, an enzyme responsible for the production of different inflammatory molecules. It relieves pain by preventing the release of bradykinin in damaged tissues.
Fibrinolytic effect: It has a significant ability to dissolve fibrin and fibrinogen, which helps maintain normal blood circulation.
Dissolve cell walls: It can penetrate the cell membranes of bacteria, fungi and viruses, and further break down macromolecules in the cytoplasm, such as proteins, nucleic acids, polysaccharides and collagen fibers, thereby playing an antibacterial and anti-inflammatory role.
What are the benefits of serrapeptase?
Anti-inflammatory
It is believed to have anti-inflammatory properties and can reduce inflammation and pain associated with arthritis and carpal tunnel syndrome.
Expectorant and detumescent
It is pharmacologically classified as an expectorant, which can dilute sputum and pus, making it easier to discharge from the body, and has anti-inflammatory and detumescent effects.
Promotes the dissolution and discharge of sputum and pus
It can reduce the viscosity of nasal secretions in patients with chronic rhinitis and promote the melting and discharge of sputum and pus. This is especially beneficial for patients with chronic sinusitis and subacute bronchitis.
Improves swelling
It can be used to improve swelling caused by surgery, trauma, chronic sinusitis or lotion stagnation.
Promotes the migration of antibiotics to the lesion site
It can promote the migration of antibiotics to the lesion site and enhance the antibacterial effect of antibiotics.
Dissolves fibrin and bradykinin
It can decompose fibrin and bradykinin, and has anti-inflammatory, detumescent and expectorant effects.
Preparation method of serrapeptase
Strain selection and genetic modification
- Select suitable strains for production, such as Serratia marcescens.
- Use genetic engineering technology to modify the strains to improve their enzyme production capacity and stability.
Fermentation process
- The modified strains are fermented on a large scale, and the appropriate temperature, pH value and nutrients need to be controlled during the fermentation process.
- After the fermentation is completed, the fermentation broth is separated by centrifugation or filtration.
Enzyme extraction and purification
- The bacteria are collected by centrifugation and then washed with appropriate buffer.
- Use ultrasound or chemical methods to break the bacteria and release it.
- The enzyme is purified by protein chromatography technology, such as ion exchange chromatography, gel filtration chromatography, etc.
Preparation and testing
- The purified serrapeptase is prepared to form the final product form.
- The product is quality tested to ensure that its purity and activity meet the standards.
What is the application industry?
Medicine: It is mainly used to relieve swelling caused by surgery, trauma, chronic sinusitis, etc., and to treat symptoms such as thick sputum and difficulty in expectoration. It is also suitable for autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus, and has the effects of inhibiting inflammatory response, promoting wound healing and inhibiting fibrosis.
Nutritional health products: It can be used in nutritional health products, using its ability to hydrolyze protein to provide the required nutrients and improve the texture of the product.
Food: It is used in the food industry for the processing of dairy products, meat products, baked goods, etc., and its main function is to improve the taste and texture of food.
Cosmetics: It is used in cosmetics, such as facial cleansers, beauty creams, etc., to improve the use effect of the product.
Feed: It is an endoprotease that can decompose large molecular proteins into products such as polypeptides and amino acids to form a unique hydrolyzed flavor. It is widely used in the hydrolysis of animal and plant proteins to produce advanced condiments and food nutrient enhancers.
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