What Does Reishi Extract Do?
What is Reishi?
Reishi is also known as Ruicao, Muzhi, Junzhi, etc., and the Japanese call it Wannian antler, which is the whole plant of Zizhi or Chizhi in the Polyporaceae plant. As a medicine, Ganoderma lucidum was first recorded in the "Shen Nong's Materia Medica" in the Han Dynasty. Ancient medical experts believed that Ganoderma lucidum can treat many diseases, and it is a precious medicine that nourishes and strengthens the body and strengthens the body. Ganoderma lucidum is sweet in nature and flavor, flat, and enters the heart, lung, liver, and kidney meridians. Function benefits essence and protects the mind, strengthens the tendons and lusters, invigorates the kidney and fills the ears, dispels wind, and eliminates numbness. Indications for asthenia, fatigue, anorexia, cough, asthma, insomnia, and other diseases.
Reishi Mushrooms Extract (Reishi Mushrooms Extract) is a product extracted from the mycelium of Ganoderma lucidum K., etc., and contains chemical components such as ergosterol, fungal lysozyme, trehalose, and coumarin.
The chemical components contained in Ganoderma lucidum are very complex, including the following categories:
1. Polysaccharides: There are more than 60 kinds of Ganoderma lucidum polysaccharides and their monosaccharide compositions that have been determined.
2. Amino acids: The types of amino acids in Ganoderma lucidum and Ganoderma lucidum are similar, but their contents are different. The amino acids contained include aspartic acid, glutamic acid, arginine, lysine, ornithine, proline, Alanine, glycine, serine, threonine, tyrosine, valine, leucine, phenylalanine, isoleucine, hydroxyproline, histidine, methionine, etc., and red sesame spores were found There are sulfur-containing amino acids in the powder.
3. Trace elements: organic germanium is the main active ingredient. The content of organic germanium is 4 to 6 times that of ginseng, which is a powerful immune enhancer.
4. Alkaloids: The content of alkaloids in Ganoderma lucidum is relatively low. The alkaloids we obtained from Chizhi spore powder and Ganoderma lucidum include choline, betaine, and their hydrochlorides, and Ganoderma lucidum Ganoine, Ganodine, and Niacin.
5. Triterpenoids: Triterpenoids are one of the main components of Ganoderma lucidum, many of which have physiological activities. It is reported that Ganoderma acids A, B, C, and D can inhibit the release of histamine in mouse muscle cells. Ganoderma acid F has a strong activity of inhibiting angiotensinase. Chizhi sporadic acid A can reduce the transaminase elevation in mice caused by CC14, galactosamine, and propionibacterium.
6. Adenosine: Ganoderma lucidum adenosine is a substance whose basic structures are nucleoside and purine. It is one of the main components of Ganoderma lucidum. There are Ganoderma lucidum purine, adenine, adenosine, uracil, uridine, and so on. Adenosine has an anticoagulant depolymerization effect.
7. Oils and fats: stearic acid, arachidic acid, behenic acid, etc.
8. Sterols: The content of sterols in Ganoderma lucidum is relatively high, and the content of ergosterol alone reaches about three thousandths. It is known that there are nearly 20 kinds of sterols isolated from Ganoderma lucidum, and their skeletons are divided into two types: ergosterols and cholesterol. For the extraction and separation of sterol compounds, ethanol is used to extract the raw materials, then extracted with ether, and then the ether solution is extracted with NaHCO3 aqueous solution to remove the acidic part, and then the sterol compounds are separated by silica gel column chromatography. There are few reports on the physiological activities of sterol compounds. The currently known active ingredients are mainly triterpenoids and polysaccharides of Ganoderma lucidum.
What does Reishi Extract do?
(1) Improving non-specific immune function Ganoderma lucidum polysaccharide can improve the immune function of the body, enhance the phagocytosis of macrophages, and improve the function of granulocytes. Significantly promote lymphocyte proliferation.
(2) Enhancing the activity of NK can eliminate the inhibitory effect of chemical drugs, such as cyclophosphamide, on lymphocytes; significantly increase the activity of natural killer cells (NK), and reduce the inhibitory effect of chemical drugs on NK cells.
(3) Promote the production of interleukin Ganoderma lucidum polysaccharide can improve the ability of activated macrophages to produce interleukin-1 (IL-1); and can promote the production of interleukin-2 (IL-2) by splenocytes
(4) Promoting the production of tumor necrosis factor (TNF) Ganoderma lucidum polysaccharide can promote the production of tumor necrosis factor by macrophages, causing tumor hemorrhage and necrosis, and directly killing tumor cells. Ganoderma lucidum extract can induce the transformation of the body's immunity to Th1 type, improve the basic immune function of the tumor-bearing body, and combine with immunotherapeutic agents such as CpG-ODN or HSP70-PCs can enhance the effect of immunotherapy.
(5) Enhancing the activity of DNA polymerase a in immune cells Ganoderma lucidum polysaccharide can promote the activity of DNA polymerase a in spleen cells, enhance DNA synthesis and cell proliferation in immune cells, and accelerate the immune response.
(6) Regulating humoral immunity The effect of Ganoderma lucidum on humoral immunity is biphasic. It not only has the side of improving humoral immunity, but also has the side of inhibiting humoral immunity and anti-allergic reaction. This may be related to the complex ingredients contained in Ganoderma lucidum. Ganoderma lucidum polysaccharide can improve humoral immunity, improve delayed hypersensitivity, and increase IgG content. Ganoderma lucidum also inhibits humoral immunity, and has obvious inhibitory effects on lymphocyte DNA synthesis and T cell and B cell transformation induced by concanavalin A (ConA).
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