What Does Phosphatidylserine Do For The Brain?
Phosphatidylserine Powder Bulk is a type of phospholipid, which is a broad name for phosphoric acid-containing lipids. The phospholipid family has numerous members, covering PC, PE, PI, PS, PA, and PG. Natural phospholipids serve an important role in cell membrane composition and functional activities as one of the fundamental components.
Phosphatidylserine (PS) was first extracted and characterized by Jordi Folch in 1942, and its chemical structure was elucidated by Baer and Maurukas in 1952, confirmed through chemical synthesis.PS makes up around 18% of all phospholipids in the brain and is a crucial component of human brain neurons. Because PS is the only phospholipid in cell membranes with a negative charge in comparison to other phospholipids, it plays a key function in creating unique anchoring sites on the inner membrane of neurons. These anchoring sites are necessary for the normal functioning of neurons.
What does Phosphatidylserine Powder Bulk do for the brain?
PS is the only phospholipid able to repair brain injury, enhance memory, and regulate the functional status of important proteins in cell membranes.
One of the primary components of brain neurons, PS can support and stimulate the action of several brain enzymes. Additionally, it can help to repair and replace damaged brain cells, slow down the loss of neurotransmitters, and remove dangerous compounds.
In the study by Suzuki S et al., elderly rats with memory impairment were subjected to the Morris water maze escape test. After feeding with soybean-derived soybean phosphatidylserine (SB-tPS) for 60 days, the results showed a significant improvement in the behavior of male elderly rats. The study also found that PS products can promote acetylcholine release and Na+/K+-ATPase activity. With increased acetylcholine accumulation in the brain, the information transmission speed between brain nerve cells is accelerated, thereby promoting brain function, enhancing memory, and improving thinking and analytical abilities.
In the study conducted by Tang Yong, Zhang Qianyong, and others on high school students aged 17 to 18, the improvement of memory was investigated by adding 0.08% pure 50% phosphatidylserine to fresh milk. The results showed a significant improvement in the memory of students who consumed milk with added PS.
In 1986, Delwaide PJ first reported that PS products could improve patients' cognitive abilities. Subsequent double-blind and placebo-controlled studies in Europe and the United States confirmed the efficacy of PS. According to Dr. Parris M. Kidd's summary of double-blind clinical trials of PS, Crook T et al. studied 51 AD patients who took PS or a placebo for 12 weeks (100mg, 3 times a day). The results showed improvement in several cognitive abilities for patients who took PS products, while the control group did not show such results. Another double-blind placebo-controlled study indicated that daily consumption of 300mg PS for 3 to 12 weeks in early-stage Alzheimer's disease patients showed mild improvement, as demonstrated by Cenacchi T et al. A more comprehensive clinical trial involving 494 elderly dementia patients further proved that PS, as a dementia drug, can improve behavioral and cognitive performance without significant side effects. Engel RR conducted a double-blind experiment with 33 patients with mild primary degenerative dementia, who took 300mg of PS or a placebo daily for 8 weeks. The findings revealed that the majority of PS-treated patients scored more favorably clinically than placebo-treated patients, and their brain electroencephalogram (EEG) signal fractal strength tended toward normal ranges, indicating a better state of health.
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