What does hirudin do?
What does hirudin do?
Hirudin is an active ingredient extracted from leeches and their salivary glands. It is a small molecule protein polypeptide composed of 65-66 amino acids. It has a strong inhibitory effect on thrombin and is the strongest natural specific inhibitor of thrombin found so far.
Hirudin plays an important role in the field of medicine. Leeches have been used for medical treatment since ancient times, and the research and understanding of hirudin have gradually deepened with the development of science and technology. In animal taxonomy, leeches are divided into two categories: blood-sucking and non-blood-sucking. Modern research shows that the salivary glands of blood-sucking leeches are rich in natural hirudin.
Hirudin has strong stability and a small molecular weight. It has certain application value in medicine, beauty and other fields. For example, it plays an important role in preventing blood coagulation, dissolving blood clots, protecting the endothelium of blood vessels, inhibiting tumor growth, etc. It can also be used for beauty and removing cholesterol.
What are the effects of hirudin?
Anti-inflammatory, redness-removing, and repairing red acne marks
Hirudin has a certain anti-inflammatory effect on inflammatory acne and can help relieve red and swollen acne. In addition, it can also improve blood circulation, speed up blood flow, help calm the expansion of capillaries after acne subsides, and repair red acne marks.
Autonomous penetration and promotion of absorption
Because the molecular weight of hirudin is very small, it can autonomously penetrate deep into the skin and provide nutrients to cells. At the same time, it can also help the skin absorb other ingredients better and play a role in promoting penetration.
Inhibit melanin formation
Hirudin can stimulate fibroblast activity, enhance the structure of extracellular matrix, protect damaged skin, inhibit or reduce the formation of melanin, thereby having the effect of whitening and sun protection, and can delay skin aging to a certain extent.
Inhibit scar formation
Hirudin has good anticoagulant and antithrombotic effects, has a certain ability to repair skin trauma, promotes wound healing, and inhibits scar formation.
Anticoagulation and thrombolysis
Hirudin is a specific inhibitor of thrombin, which can form a stable non-covalently bound reversible complex with thrombin in a 1:1 manner, thereby preventing the coagulation process, which makes it not only able to inhibit venous thrombosis, but also has significant therapeutic effects on carotid artery thrombosis, coronary artery thrombosis and microthrombosis caused by vascular wall damage and diffuse intravascular coagulation (DIC).
Improve blood circulation
Hirudin has the effects of promoting blood circulation, anticoagulation and removing blood stasis, etc. It can improve blood circulation, fight against platelet aggregation and thrombosis, and is suitable for a variety of diseases related to blood fluidity.
Antithrombotic
Hirudin has antithrombotic effects and can be used to treat thrombotic diseases, such as cerebral thrombosis and coronary atherosclerotic heart disease. If the patient has thrombotic diseases, hirudin can be used for treatment under the guidance of a doctor, which usually has a certain effect.
Anti-fibrosis
Hirudin can inhibit the growth and proliferation of fibroblasts, reduce fibrin deposition, promote collagen dissolution, and fight against the fibrosis process.
Immunity enhancement
Hirudin has the function of preparing the internal environment, making the blood in the body weakly alkaline, removing waste from the body, strengthening cell vitality, strengthening resistance, maintaining balance in all aspects, and enhancing the body's immunity.
Cardiovascular health
Hirudin helps prevent and treat cardiovascular diseases such as coronary heart disease and angina pectoris by improving vascular health and reducing blood viscosity.
Effects of Hirudin on Skin Aging
Delaying skin aging: Hirudin can stimulate the activity of fibroblasts and enhance the structure of the extracellular matrix, thereby controlling or regulating the skin aging process to a certain extent and delaying skin aging.
Inhibiting melanin formation: Hirudin has the effect of whitening and sun protection. It can protect damaged skin and inhibit or reduce the formation of melanin.
Improving blood circulation: Hirudin can improve blood circulation, speed up blood flow, and help the skin's nutrition supply and metabolism.
Specific improvement effects of hirudin on blood circulation
Improve microcirculation
Hirudin can promote blood circulation, especially in the microcirculatory system. Microcirculation refers to the blood circulation between capillaries and tissues, which directly affects the blood supply of various organs in the body. Hirudin can soften capillaries, reduce platelet aggregation and fibrin formation, increase blood fluidity in microcirculation, and improve the blood transport capacity in microcirculation, effectively improving the blood supply of local tissues.
Increase oxygen supply
Hirudin can also increase oxygen supply. Oxygen is a substance necessary for maintaining cell life activities and plays an important role in cell metabolism and function maintenance. Hirudin can soften blood vessels, increase blood flow, and transport oxygen to the location of cells more quickly.
Improve cell utilization ability
Hirudin can promote metabolism in cells and improve cells' ability to absorb and utilize nutrients. By improving the metabolic state of cells, hirudin helps to improve the functional level of tissues and organs, thereby improving the overall microcirculation of the human body.
Protective effect on cardiovascular and cerebrovascular system
Hirudin has a protective effect on cardiovascular and cerebrovascular system. The smooth microcirculation is closely related to cardiovascular and cerebrovascular health, and hirudin can protect the normal function of cardiovascular and cerebrovascular system through various ways. It can regulate vascular tension, reduce blood viscosity, prevent thrombosis, and thus reduce the risk of cardiovascular and cerebrovascular diseases. In addition, hirudin also has anti-inflammatory and antioxidant effects, further improving the overall health level of cardiovascular and cerebrovascular system.
Treatment for varicose veins
Hirudin has a significant effect on reducing the blood rheology indexes of normal and blood stasis model rats, thus reducing blood viscosity, accelerating blood flow, improving blood circulation, and promoting metabolism. This shows that hirudin can effectively improve the symptoms of varicose veins, by improving blood rheology properties, reducing red blood cell aggregation, and increasing microcirculatory blood perfusion.
Thrombus removal
Hirudin has a strong anticoagulant effect, which can quickly dissolve blood clots and restore normal blood circulation. It can block the generation of thrombin, thereby reducing the formation of blood clots, and can activate plasminogen, converting it into plasmin, thereby dissolving the fibrin in the blood clots.
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