What Does Cassia Seed Extract Do?

What Does Cassia Seed Extract Do?

Cassia Seed Extract is a substance extracted from the dried mature seeds of Cassia or Cassia sibiricum, a plant of the Leguminosae family. These seeds contain a variety of active ingredients, including emodin, chrysophanol, physophanol methyl ether, cassia, cassia and its glycosides. Cassia Seed Extract has a variety of effects, such as clearing away heat and improving eyesight, moistening the intestines and promoting bowel movements, and has been found in modern research to have a variety of pharmacological effects such as lowering blood lipids, lowering blood pressure, protecting the liver, and purging. Cassia Seed Extract is to separate the active ingredients in Cassia Seed through a specific extraction method, so as to facilitate its application in multiple fields such as medicine, food, and cosmetics, thereby giving full play to the value of the pharmacological effects of Cassia Seed itself.

What are the functions of Cassia seed extract?

Protect the liver

The anthraquinone components contained in Cassia seed have good antibacterial activity and have inhibitory effects on Staphylococcus, Escherichia coli, etc. These components achieve a protective effect on the liver by inhibiting bacterial respiratory metabolism and intervening in the formation of bacterial biofilms.

Reduce blood lipids

Cassia seed extract has a regulating effect on blood lipids. In animal experiments, Cassia seed extract can reduce low-density lipoprotein cholesterol and triglycerides in the serum of hyperlipidemic animals to a certain extent, and can assist in increasing serum high-density lipoprotein cholesterol levels. This helps to improve blood lipid metabolism and prevent and treat hyperlipidemia-related diseases such as atherosclerosis. Its mechanism of action may be related to components such as anthraquinones in Cassia seed extract, which may be involved in regulating the synthesis, transport and metabolism of lipids in the body.

Lower blood pressure

Modern pharmacological studies have shown that Cassia seed extract has a blood pressure lowering effect. It may lower blood pressure by affecting the contraction and relaxation of blood vessels, regulating hormone levels in the body, or improving the neural regulation of the cardiovascular system. For patients with hypertension, Cassia seed extract may be a potential auxiliary treatment drug, but its specific application requires more clinical research to determine its safety and effectiveness.

Clearing the liver and improving eyesight

Cassia seed extract belongs to the liver and large intestine meridians, and has the effect of clearing the liver and improving eyesight. In traditional medicine, it is often used to treat eye diseases such as wind-heat red eyes, amblyopia, and nymphoma. Modern research has found that its eye-improving effect may be related to ingredients such as carotene (vitamin A substances) contained in it. In addition, Cassia seed extract can also relieve symptoms such as eye fatigue and dryness, and has a certain health care effect for people who use their eyes for a long time, such as office workers or students who often use electronic devices.

Antibacterial and anti-inflammatory

The anthraquinone components contained in Cassia seed have good antibacterial activity. Cassia seed extract has an inhibitory effect on bacteria such as Staphylococcus, Escherichia coli, Corynebacterium diphtheriae, Salmonella typhi, and Salmonella paratyphi, and also has an inhibitory effect on fungi such as Microsporum audouinense, Trichophyton sphaeroides, and Microsporum gypseum. The mechanism of its antibacterial effect is to inhibit the respiratory metabolism of bacteria, interfere with the formation of bacterial biofilm, etc., so as to achieve the effect of antibacterial and anti-inflammatory, which has certain significance in the prevention and treatment of infectious diseases in the medical field.

Moisturizing and laxative

The taste of Cassia seed extract includes sweet, bitter and salty, and its property is slightly cold. Since it belongs to the large intestine meridian in traditional Chinese medicine theory, it has the effect of clearing heat and moistening the intestine and laxative, and is particularly suitable for treating constipation caused by dry intestines. It can increase intestinal peristalsis and promote defecation, which is a more natural treatment option for patients with habitual constipation. However, people with qi deficiency and loose stools should not take products containing Cassia seed extract, because its coldness may aggravate the symptoms of loose stools.

How does cassia seed extract affect blood lipid levels?

Reduce blood lipid content

1. Reduce total cholesterol (TC) and low-density lipoprotein cholesterol

The active ingredients in cassia seeds, such as emodin and aloe-emodin, have the effect of inhibiting cholesterol synthesis and promoting its metabolism. These ingredients can reduce the levels of TC and LDL-C in plasma, thereby helping to lower blood lipid levels.

Clinical studies have shown that taking cassia seed extract can significantly reduce total cholesterol and LDL cholesterol levels. For example, one randomized controlled trial showed that after taking cassia seed extract for 12 weeks, subjects experienced a 10% reduction in total cholesterol levels and a 13% reduction in LDL cholesterol levels.

2. Increase high-density lipoprotein cholesterol

Cassia seed extract can increase the content of HDL-C in plasma. HDL-C is a "good" cholesterol that helps transport excess cholesterol from peripheral tissues back to the liver for metabolism and excretion, thereby protecting cardiovascular systems.

The same clinical study also showed that subjects' HDL cholesterol levels increased by 12% after taking cassia seed extract.

Regulates expression of genes related to fat metabolism

Up-regulating lipolysis genes: Cassia seeds can up-regulate the transcriptional expression of genes such as PPARy, SREBP-1c, HSL and TGH in adipose tissue. These genes are involved in the decomposition process of fat and help reduce the accumulation of fat in the body.

Down-regulates fat synthesis genes: At the same time, Cassia seeds can also down-regulate the expression of fat synthesis genes such as FAS, reduce fat synthesis, and further reduce blood lipid levels.

Antioxidant and anti-inflammatory

Certain components in Cassia seed extract, such as isorhamnetin, quercetin and other flavonoids, have antioxidant and anti-inflammatory effects. These ingredients can reduce lipid deposition in blood vessel walls and protect vascular endothelial cells from lipid peroxidation damage, thus helping to maintain normal levels of blood lipids.

Antioxidant mechanism of Cassia seed extract

Free radical scavenging

Cassia seed extract has strong reducing properties and can scavenge free radicals to protect cells from oxidative damage.

Among them, the polyphenolic compounds in Cassia seed can undergo oxidation-reduction reactions with free radicals and reduce free radicals to stable molecules.

Increasing the activity of antioxidant enzymes

Cassia seed extract can enhance the activity of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), thereby improving the antioxidant capacity of cells.

At the same time, Cassia seed extract activates the Nrf2 signaling pathway and induces the expression of antioxidant enzymes, thereby protecting cells from oxidative damage.

Reducing the level of intracellular reactive oxygen species (ROS)

Cassia seed extract can reduce the level of intracellular ROS, which is an important indicator of oxidative stress. High levels of ROS can lead to cell damage and aging.

Improving mitochondrial function

Cassia seed extract can improve mitochondrial function, increase mitochondrial membrane potential and ATP production, while reducing the production of mitochondrial ROS and inhibiting mitochondrial apoptosis.

What can Cassia seed extract be used for?

Food field

Health drinks：

Cassia seed extract can be added to various health drinks, such as tea drinks, fruit juice drinks, sports drinks, etc. As a natural health ingredient, it can increase the effects of lowering blood lipids, lowering blood pressure, clearing the liver and improving eyesight for drinks. For example, in Cassia seed tea, Cassia seed extract is the main active ingredient, and people drinking Cassia seed tea can play a role in health care. At the same time, Cassia seed extract can also be used as a natural pigment and flavoring agent to improve the color and taste of the drink, and during the addition process, the amount of addition needs to be strictly controlled to ensure compliance with relevant national standards.

Dairy products：

Adding Cassia seed extract to dairy products can improve the antioxidant capacity and nutritional content of the product and extend the shelf life of the product. For example, adding an appropriate amount of Cassia seed extract to yogurt, milk and other products can not only increase the health functions of the product, such as lowering blood lipids, clearing the liver and improving eyesight, but also use its antioxidant properties to prevent the oxidation and deterioration of dairy products, and improve the quality and shelf life of the product.

Baked goods：

Adding cassia seed extract to baked goods can improve the color and taste of the product, while giving the product certain health functions. For example, when cassia seed extract is added to the production process of baked goods such as bread and biscuits, consumers can not only enjoy the delicious taste when eating these foods, but also get the health benefits brought by cassia seed extract, such as helping to regulate blood lipids and blood pressure.

Cosmetics field

Cassia seed extract has antioxidant and anti-inflammatory effects, and can be used as a cosmetic raw material to reduce acne and inhibit sebum secretion. In skin care products such as creams, lotions, and facial cleansers, adding cassia seed extract can use its antioxidant effect to resist skin aging and reduce the damage of free radicals to skin cells; its anti-inflammatory effect helps to reduce skin inflammation and has a certain improvement effect on skin problems such as acne and blackheads; and by inhibiting sebum secretion, it can improve the condition of oily skin and make the skin more refreshing and healthy.

Medical field

Treatment of cardiovascular and cerebrovascular diseases

The active ingredients such as anthraquinones, glycosides and lactone substances in Cassia seed extract have been widely used in the clinical treatment of various cardiovascular and cerebrovascular diseases, such as hypertension, hyperlipidemia, etc. In the treatment of hypertension, Cassia seed extract may play a role by regulating the physiological mechanism related to blood pressure; for hyperlipidemia, it helps to improve blood lipid levels and reduce the risk factors of cardiovascular disease. In addition, Cassia seed extract may also have a certain preventive and auxiliary therapeutic effect on cardiovascular and cerebrovascular diseases such as coronary heart disease.

Antibacterial and anti-inflammatory drugs

Since Cassia seed extract has an inhibitory effect on a variety of bacteria and fungi, it has potential application value in the research and development of antibacterial and anti-inflammatory drugs. It can be used as a natural antibacterial ingredient and added to drugs to treat infectious diseases caused by sensitive bacteria, such as skin infections, respiratory infections, etc. Compared with traditional antibiotics, Cassia seed extract has the advantages of being natural and having relatively few side effects, but its antibacterial effect and mechanism of action need further in-depth research.

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