What can ergothioneine powder do?
What can ergothioneine powder do?
Ergothioneine is a natural amino acid present in many organisms. It was first discovered by French pharmacist Charles Tanret in 1909 when he was studying ergot fungi that destroy rye grains. It is produced by edible fungi represented by Ganoderma lucidum, and is also widely distributed in animal and plant tissues. It can protect cells in the human body and is an important active substance in the body.
It is a homologous component in the human body, which accumulates in high concentrations in various cells and tissues in the human body. It is most abundant in red blood cells, bone marrow, liver, kidneys, and the lens and cornea of the eye. However, our human body cannot synthesize ergothioneine by itself and can only be ingested from the outside. EGT is widely found in edible fungi, such as boletus, gray oyster mushrooms, shiitake mushrooms, king oyster mushrooms, and hericium erinaceus.
It is a natural antioxidant with super antioxidant properties. It can protect and maintain the biological activity of other antioxidants in cells, remove excessive free radicals to protect mitochondria, and protect cells and DNA in the human body. t is called a cell preservative and cell guardian, and is also known as the "Hermes" in the antioxidant world.
What does ergothioneine do?
Anti-aging
Its anti-aging effect is particularly prominent, which can delay the process of cell aging, improve the vitality of skin cells, and prevent skin photoaging. By inhibiting the activity of melanocytes and the glycation reaction of skin proteins, ergothioneine can reduce the production of melanin and make the skin brighter. In addition, it can prevent the loss of skin elasticity due to aging, improve facial contours, and reduce the appearance of orange peel. Scientific research shows that the anti-aging function is mainly reflected in three aspects: anti-oxidation, anti-photoaging and protection of mitochondria. It can also be understood as protection against UV damage, scavenging free radicals, smoothing, firming and wrinkle removal.
Antioxidant
Its antioxidant mechanism is mainly due to its unique chemical structure. It contains sulfur atoms and multiple hydroxyl groups, which react with free radicals through the highly specific organic cation transporter OCTN-1, thereby neutralizing the activity of free radicals and preventing them from damaging cells. In addition, it can promote the activity of other antioxidant enzymes in cells to jointly resist oxidative stress. Compared with old antioxidant players such as vitamin C, glutathione, coenzyme Q10, and astaxanthin, ergothioneine is not only more stable, more efficient, and safer, but also has stronger antioxidant capacity.
Anti-inflammatory
The inflammatory response in the body is a common defensive natural response to stimulation, and it is also a manifestation of the body's struggle with damaging factors. Ergothioneine can inhibit the production of inflammatory factors, reduce the degree of inflammatory response, and relieve skin discomfort. It exerts anti-inflammatory effects by regulating the signal pathways in cells and inhibiting the expression of inflammation-related genes. For example, for sensitive skin or acne skin, it can help reduce inflammation and pigmentation and promote skin repair.
Whitening and spot removal
It can inhibit tyrosinase. Tyrosine in the human body can be converted into melanin under the action of tyrosinase, making the skin darker. There are laboratory studies that ergothioneine can inhibit tyrosinase activity, and play a role in spot whitening. It has coenzyme-like properties, participates in a variety of biochemical activities in the human body, absorbs ultraviolet rays, can prevent and treat skin photoaging, inhibit the saccharification reaction of skin proteins, reduce melanin production, and has a skin-lightening effect. When used together with other antioxidants, it has a good synergistic whitening effect.
Anti-inflammatory mechanism of ergothioneine
Inhibit the generation of inflammatory mediators: It can inhibit the generation of inflammatory mediators, reduce the role of inflammatory mediators in the inflammatory process, and thus reduce the inflammatory response.
Inhibit the activity of inflammatory-related enzymes: It can inhibit the activity of these enzymes, reduce the generation of inflammatory mediators, and thus reduce the inflammatory response.
Inhibit inflammation-related signaling pathways: It can inhibit the activation of these signaling pathways, thereby reducing the inflammatory response.
Inhibit oxidative stress: It has an antioxidant effect, which can remove free radicals in cells and reduce the level of oxidative stress, thereby reducing the inflammatory response.
Promote the generation of anti-inflammatory factors: It can promote the generation of some anti-inflammatory factors, such as nitric oxide (NO), interleukin-10 (IL-10), etc. These anti-inflammatory factors can inhibit the inflammatory response and reduce the symptoms of inflammation.
Regulate the function of immune cells:It can regulate the function of immune cells and enhance the body's ability to remove pathogenic microorganisms and damaged tissues, thereby reducing the inflammatory response.
The skin anti-aging mechanism of ergothioneine
Based on its strong antioxidant properties, high stability, and non-toxicity, it has been gradually confirmed by more and more studies to have a positive impact on human health, especially in inhibiting skin aging.
Maintaining collagen in the dermis: Fibroblasts are important cells in connective tissue. They can secrete structural proteins such as collagen that constitute the extracellular matrix, which is closely related to the aging process of the skin. By reducing the degradation of matrix metalloproteinase-1 and increasing the production of type I collagen, it inhibits photoaging caused by UV and reduces collagen damage by up to 72.9%.
Whitening and lightening: Tyrosine in the human body can be converted into melanin under the action of tyrosinase, making the skin darker. There are laboratory studies that ergothioneine can inhibit the activity of tyrosinase and play a role in lightening and whitening. It has coenzyme-like properties, participates in various biochemical activities of the human body, absorbs ultraviolet rays, prevents and treats photoaging of the skin, inhibits the saccharification reaction of skin proteins, reduces melanin production, and has a skin-lightening effect. When used with other antioxidants, it has a good synergistic whitening effect.
Application fields
Medical field
It is used to treat inflammatory diseases such as arthritis, and it can reduce joint inflammation by inhibiting the activation of inflammatory cells and the release of inflammatory factors.
In the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, it can penetrate the blood-brain barrier, exert antioxidant and anti-inflammatory effects, and protect neurons from damage.
Cosmetic field
Due to its strong antioxidant capacity and anti-inflammatory activity, it is widely used in skin care products to help delay skin aging and protect the skin from damage by external factors such as ultraviolet rays.
Food and health field
As a food additive, it is used to improve the taste of food and extend the shelf life. At the same time, it is also favored by consumers as a health product.
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