What are the benefits of kaempferol?

What are the benefits of kaempferol?

Antibacterial and anti-inflammatory

Studies have shown that kaempferol has good antibacterial activity and is also effective against methicillin-resistant Staphylococcus aureus (MRSA). It also has good antibacterial activity against Vibrio cholerae and Enterococcus faecalis. In terms of antiviral, kaempferol can show concentration-dependent inhibitory effects at non-cytotoxic concentrations.

Kaempferol can regulate the expression of inflammatory factors, reduce the level of pro-inflammatory cytokines, and exert anti-inflammatory effects.

Antioxidant

Kaempferol has the ability to scavenge free radicals, which can help reduce oxidative stress, thereby protecting cells from damage.

Prevention and treatment of diabetes

Kaempferol has the effect of preventing and treating diabetes. The researchers established a mouse test model to verify the effect of kaempferol on lowering blood sugar and blood lipids in diabetic mice. The diabetic model mice fed with kaempferol and the diabetic mice fed with Xiaoke pills were subjected to control experiments. The levels of serum triglycerides, total cholesterol, blood sugar, malondialdehyde, and the activities of glutathione peroxidase and superoxide dismutase in the diabetic model mice were measured. The results showed that kaempferol can effectively reduce the levels of serum triglycerides, total cholesterol, blood sugar and malondialdehyde in mice, and can significantly increase the activities of glutathione peroxidase and superoxide dismutase in serum. Among them, 10 mg/(kg·bw·d) is the best dose. The above studies have proved that kaempferol has a therapeutic effect on diabetes and can delay the development of diabetes.

Protect damaged cells

Acute liver failure is caused by alcohol, drugs, viruses and other reasons. Acute liver failure is caused by a large number of liver cell necrosis and severe liver dysfunction. In acute liver failure, endoplasmic reticulum stress-induced cell apoptosis plays an important role. Acute liver failure leads to a large number of liver cell apoptosis and necrosis. Endoplasmic reticulum stress is the key to cell apoptosis. Kaempferol was used to intervene in the acute liver failure mouse model. Kaempferol can improve the liver function and pathological changes of mice, and can inhibit the apoptosis of human hepatocyte cell line 7702 cells induced by endoplasmic reticulum stress. Kaempferol may inhibit endoplasmic reticulum stress to protect liver cells by inhibiting the expression of endoplasmic reticulum stress-specific apoptotic protein CHOP. It can be seen that the application of kaempferol may provide a new intervention measure for acute liver injury.

Anti-fertility and anti-osteoporosis

Kaempferol has obvious anti-fertility effects on animals and exhibits estrogen-like activity. Estrogen has a direct proliferative effect on osteoblasts and also significantly promotes the differentiation of osteoblasts after proliferation. According to the experimental results, the researchers concluded that kaempferol can significantly increase the bone density of ovariectomized rats and significantly inhibit the loss of bone calcium and phosphorus in rat urine. According to the results of micro-CT, kaempferol has a significant improvement on the morphological structure of trabecular bone in osteoporotic rats. Based on the above conclusions, kaempferol can treat osteoporosis.

Lowering blood lipids

Kaempferol lowers blood lipid levels by inhibiting the activity of enzymes related to fat synthesis and promoting lipid metabolism.

Inhibiting eye aldose reductase, which is beneficial for the treatment of diabetic cataracts

In addition to the above effects, kaempferol also has antitussive and expectorant, anti-ulcer, choleretic and diuretic effects.

What is kaempferol?

Kaempferol, also known as kaempferol III and flavonol, is a flavonoid type polyphenol belonging to the flavonoids. It is a yellow crystalline powder that is easily soluble in ether, hot ethanol or alkaline solution.

Flavonoids are a natural polyphenol compound with antioxidant, antibacterial, anti-inflammatory and antiviral effects. It is mainly derived from the rhizome of the ginger plant Kaempferia galanga, and is also found in various natural sources, including apples, citrus fruits, grapes, red wine, ginkgo leaves, tea, broccoli, cabbage and other green plants.

Studies have found that kaempferol has anti-inflammatory and oxidative stress in various neurological diseases, plays a role in protecting nerves, can remove excess superoxide free radicals in the human body, and can also prevent oxidative damage to DNA and cells. In addition, in addition to anti-aging, anti-inflammatory, prevention and treatment of diabetes, atherosclerosis and osteoporosis, kaempferol also has nutritional and health effects in protecting nerves, liver and myocardium, inhibiting protein kinase and other aspects. Kaempferol has a very broad market as a health food and medicine.

Kaempferol acts as an antioxidant, helping to prevent oxidative damage to cells and DNA. As such, it is thought to have a protective effect against atherosclerosis. It has anti-estrogen properties as a phytoestrogen, suggesting that it can block estrogen binding by binding to estrogen receptors.

What role does kaempferol play in anti-aging?

The antioxidant properties of kaempferol are very effective in anti-aging. It can help protect the skin from environmental factors and slow down cell aging, thereby maintaining the skin's elasticity and radiance. In addition, kaempferol has also been studied for delaying age-related cognitive decline.

What foods can we consume kaempferol through?

To increase your intake of kaempferol, you can choose foods rich in this compound. Red wine is the most well-known source, especially those made from black grapes. In addition, fresh grapes, blueberries, nuts, and even cocoa and dark chocolate are also good choices.

What is kaempferol used for?

Kaempferol has strong anti-inflammatory activity and can inhibit the generation and release of a variety of inflammatory mediators, especially prostaglandins, leukotrienes and arachidonic acid, which has a specific and strong inhibitory effect on inflammatory mediators, thereby playing an anti-inflammatory role.

Kaempferol also has antiviral effects and can inhibit the growth of a variety of viruses and bacteria, such as influenza virus, polio virus, Staphylococcus aureus, Salmonella typhi, etc. It can be used clinically to treat viral colds, viral hepatitis and other diseases.

Kaempferol also has anti-thrombotic effects and can inhibit the aggregation of platelets, thereby playing an anti-thrombotic role

It can treat cough and bronchitis.

It is beneficial for the treatment of diabetic cataracts.

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