Discover The Health Benefits Of Gypenoside: Nature's Miracle Ingredient
Gynostemma Pentaphgllum(Thunb) Makino is a perennial grassy vine of the cucurbit family. Because of its bitter taste, it is also called seven-leaf bile in folk. Introduced from Japan for sweet type, also known as sweet tea vine. It is a kind of traditional and precious Chinese medicine, which has a long history of application in Chinese folk, and it was first published in the Ming Dynasty, and the Tang Materia Medica, Compendium of Materia Medica and other famous Chinese medicine books are recorded in detail.
The main active component of gypenoside is gypenoside. Since the Japanese scholar Nagai et al. isolated panaxanediol and ZX-hydroxypanaxanediol in 1976, 83 saponins, collectively referred to as gypenosides, have been isolated and extracted from the human research on gynostemma gypenosides, which belong to the structure of dalma fatty anols. Among them, gypenosides 3,4,8,12 and ginsenosides Rb1, Rb3, Rd, F2 are identical in chemical structure, and the rest can be regarded as protopanaxanediol or panaxantriol isomers. Gypenoside K can be obtained by enzymolysis of gypenoside 1-16, gypenoside V-AH is the same as ginsenoside Rg3, in which the content of gypenoside 8 is 8 times that of ginsenoside Rd, and the total saponin content is 3 times that of ginseng. Through pharmacological studies, it has been proved that gypenoside has the adaptogenic effect of ginseng and is a strong agent. At the same time, it has anti-cancer, anti-ulcer, anti-lipemia, sedation, anti-fatigue and prolong cell life, so it is known as the "southern ginseng" reputation. In addition, Gypenoylum also contains flavonoids, sugars and a variety of amino acids necessary for the human body, vitamins and trace elements such as selenium, zinc, iron, manganese.
Based on the important health care function of gynostylus gibbosa on human body, the application research of gynostylus gibbosa at home and abroad is becoming more and more mature, and it is widely used in cosmetics, food, health care products, drugs and other industries.
"Back to nature" is the general slogan of the current international cosmetics industry, and advanced countries attach great importance to the development of natural cosmetics. In this case, Chinese herbal medicine is favored, has not shown its unique charm, and plays an incomparable advantage in the cosmetics industry. Because of its extensive and significant role, gynostylus is increasingly attracting the attention of cosmetic manufacturers.
The active effect of gynostaphyllus on human skin is mainly reflected in the following aspects:
1. Anti-aging effect. Usually, when age spots (also called lipofuscin) and brown spots and freckles form, lipid peroxide can be found in large quantities in the skin and increased. When people are young, the ability to decompose and excrete lipid peroxide is strong, and this effect gradually weakens with age, resulting in the aging of skin cells.
The total saponins of gypenoside can significantly reduce and inhibit the production of lipid peroxide, protect the skin cell membrane from damage, and prevent cell senescence. The results showed that the total saponins of gypenosides could significantly prolong the cell life of fetal diploid fibrocytes and human Verner syndrome skin cells. In vitro culture of human skin cells, adding the culture medium of 0.2% gypenoside, the cells can be passed from 22 generations to 27 generations, that is, the life span of cells can be extended by 22.7%, so gypenoside has an active effect on skin cells and can accelerate skin
Renewal of surface cells, delay skin aging. The anti-aging effect of Gypenoch on the body is due to the fact that it can increase the activity of antioxidant enzymes such as superoxide dismutase (SOD) in the human body and skin epidermal cells, strengthen the elimination of active oxidation free radicals, and improve the metabolism of the body.
2. Improve skin microcirculation. The experiment showed that the total glucoside of gypenoside can improve the microcirculation of the skin significantly, and the blood circulation of the skin is full, and the skin is moist and glossy.
3. improve the resistance of the skin, prevent skin cells from becoming cancerous. Experiments show that the total glucoside of gypenoside can improve the immunity of the body and resist the skin infection. It was proved by cell culture that the total glucoside of gypenoside can inhibit cell canceration, and the killing rate of tumor cells is as high as 91%. Therefore, it can protect the skin and prevent skin cancer.
Gypenoside contains a variety of ginsenosides, which can promote the degradation of skin cutin like ginseng; Proliferation and metabolism of epidermal germinal layer cells; Skin collagen fiber renewal, parallel arrangement and other functions can make the skin tender and elastic. In addition to ginseng saponins, Gypenoside also contains a variety of amino acids, vitamins and trace elements, which synergies with the skin moistening effect, can eliminate dark spots, prevent rough skin.
Anti-ultraviolet damage, anti-roughness and creasing effect. Sunlight, ultraviolet light, ozone, nitrogen oxides and most industrial pollutants induced the generation of active oxygen radicals, which led to the oxidation of sulfhydryl groups of skin melanocytes or directly increased the activity of coolinase. Thermal radiation can also increase the tyrosine-tyrosinase reaction, so that the skin melanin increase, the skin darkening; A local increase in melanin can lead to freckles or browns blotch. Experiments have proved that cosmetics with gypenoside as the active ingredient can resist the effects of ultraviolet and sunlight on the skin, prevent skin tanning, and reduce or even fade black and brown spots. In addition, the total glucoside of gypenoside has the effect of anti-roughness and anti-wrinkle cracking, and then plays the dual role of beauty and health care.
6. Stabilize the spirit and prevent haggard effects. Mental disorders, too excited, poor rest, coupled with fatigue, will lead to body metabolism disorders, make people gaunt, skin lose luster and elasticity, prone to wrinkles, appear old. The total glucoside of gypenoside has the function of stabilizing spirit, relieving tension and anti-fatigue, which can make people refreshed, red face, not easy to produce wrinkles, and appear young and energetic.
7. The hydrophilic composition of gypenoylum can significantly inhibit the production of free fatty acids and the synthesis of neutral fat by fat cells, and prevent the conversion of glucose into fat, so it can play a role in weight loss through the regulation of fat metabolism.
Human obesity is not an increase in the number of fat cells, but an increase in the thickness of subcutaneous fat due to the increase in the volume of fat cells. The number of pulses per minute (CPm) of adipocytes were measured after the adipocytes and the tracer compound C14-glucose were cultured at 37℃ for half an hour, and the index of glucose entering the cells to synthesize neutral fat was determined. The number of CPm measured per gram of adipocytes was only about 50% of that in the non-added group. It shows that the hydrophilic composition of gynostaphyllum can inhibit the synthesis of neutral fat by fat cells, reduce the size of fat cells, and thus have the effect of weight loss. Oral gyro blue bodybuilding tablets (tablets made of hydrophilic ingredients) reduce fat synthesis from an overall perspective, and local application can make the drug directly act on the thickness of subcutaneous fat, thus playing a weight loss, bodybuilding effect.
Gypenoside is used in hair washing and hair care products, and has the following functions:
1. Improve hair microcirculation, make epidermal germinal layer cell metabolism vigorous, skin collagen fiber renewal and enhancement, and can prevent hair early white and treat senile alopecia. Studies have shown that gynostemus can reduce white hair in old age from 80% to 50%, 40% to 25%, and 25% of white hair can be all black after a year.
2. Inhibit cell senescence and prolong cell life. The buildup of dead scalp cells forms dandruff. The anti-aging effect of gypsetonin can prolong the life of scalp cells, reduce the generation of dandruff, and has the function of antiseptic and antipruritic.
3. anti-UV damage, nourish hair. It can prevent the hair from becoming yellow and rough due to wind and sun, and is conducive to the repair of hair damage caused by electric ironing, cold ironing, hair coloring, etc., and can make the hair oily and bright, fluffy and soft.
In addition, gypenoside has excellent surface activity, strong foaming power, emulsification, dispersion, wetting and other properties, and good washing and decontamination effect, so it is an excellent natural biosurfactant.
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