Terpinen-4-ol Liquid

What is Terpinen-4-ol？
Terpinen-4-ol is an organic compound, which exists naturally in nutmeg, cardamom, rosemary, coriander, etc. It is a colorless or light yellow oily liquid with spicy, earthy, green and woody aromas. Slightly soluble in water, soluble in alcohols and oils. For example, some tangerine peels have a mellow woody aroma and a strong aged aroma, which may be due to this. This compound is widely used in spices and agrochemical industries.
At the same time, it is also a natural monoterpene, which is the main bioactive component of tea tree oil. It inhibits the production of inflammatory mediators through activated human monocytes and can significantly enhance the efficacy of various chemotherapy and biological agents.

Biological mechanism of action:

Human body: It is a natural monoterpene and the main bioactive component of tea tree oil. It belongs to the category of monoterpene alcohols in the alcohol family. It not only has the anti-pathogen effect of alcohol, but can also increase the content of immunoglobulins, stimulate white blood cells to resist germs, and enhance the response ability of the immune system; it also has mild antibacterial and antiviral effects. The entire process relies on 4-terpenol activating human monocytes to inhibit the production of inflammatory mediators, significantly enhancing the efficacy of various chemotherapy and biological agents.

Plant: It is a botanical fungicide extracted from plants. Its mechanism of action is: affecting the permeability barrier of biological cell membrane structure, and capable of destroying cell membranes and cell walls. It has preventive and therapeutic effects at the same time, and has a bactericidal effect at different stages of the disease: in the spore germination stage, it can effectively inhibit spore germination, thereby preventing the spread of the disease; in the mycelium growth and diffusion stage, it can inhibit (living and in vitro) mycelium The growth and spread; sporangia growth stage: can inhibit the formation of fungal spores, thereby preventing it from causing infection on new plant tissues.

Uses

1. Medical field: It can inhibit the overexpression of TNF, IL-1, IL-8, and prostaglandin E2, reduce inflammatory response, and have anti-inflammatory effects. It is active against strains resistant to mupirocin, fusidic acid, vancomycin, methicillin, and linezolid. It has good anti-staphylococcal activity against a large number of Staphylococcus aureus isolates, and has good antibacterial effects on fungi such as Candida albicans that cause reproductive system problems. It can also enhance the antibacterial ability of fluconazole against Candida albicans. It can be used to make drugs and treat a variety of diseases. For example, Lanfu cream, which relieves fungal infections, uses it as the main ingredient. It can also help treat cardiovascular diseases, diabetes, hepatitis and other diseases, and is used to treat chronic pain and neurodegenerative diseases.
2. Cosmetic field: This product has good antioxidant and anti-inflammatory properties. It can improve skin quality. Reduce signs of skin aging and promote skin health and youth. In addition, it can also be used to control skin inflammation and reduce skin allergic reactions, making the skin smoother and more comfortable.
3. Food field: It can be used as a food additive to provide food with fragrance and taste. It exists in many herbs, such as mint, rosemary and thyme, and they are widely used in cooking and seasoning. In addition, because it has antibacterial and antioxidant properties, it can be used to extend the shelf life of food and maintain its essence and taste.
4. Other fields: It can be used as a ligand to form metal complexes, which can be used to catalyze chemical reactions. It can also be used as a green solvent to replace toxic organic solvents in manufacturing and chemical processes. Due to its strong stability and biocompatibility, it can also be used to prepare new materials and biomedical devices.

Synthesis

At present, the source of this compound is not only extracted from tea tree oil, but also synthesized by base-promoted 1,4-cineole rearrangement or acid-catalyzed limonene hydration. However, these synthetic processes based on corrosive, non-recyclable homogeneous reagents are non-selective and produce a large number of isomers, which makes the purification of active substances very complicated and more expensive. Therefore, researchers have conducted in-depth research and created a synthetic method with no isomers produced, only on solid catalysts such as alumina, nano-titanium dioxide and Pd/C, through selective epoxidation, isomerization of terpinolene epoxide and hydrogenation of allyl alcohol, with a yield of >60%. For the isomerization of terpinolene epoxide, the synthesis can be carried out in batch or flow mode.
 

Formulation
Capusle Formulation

Tablet Formulation

Solid Drink Formula

Certificates
YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Terpinen-4-ol and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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