Panax Notoginseng Extract

What is Panax notoginseng extract?

Panax notoginseng extract is a substance extracted from the tuberous root of Panax notoginseng, a plant of the genus Panax in the Araliaceae family. It mainly contains saponins, including ginsenoside Rb1, ginsenoside Rg1, notoginsenoside R1, etc. This extract is not only used in health care products and other fields, but also used as a formula ingredient in skin care products because it has the effects of dispersing blood stasis, stopping bleeding, reducing swelling and relieving pain. In addition, it shows physiological activity in many aspects such as the blood system and cardiovascular system. The extract has the effects of dispersing blood stasis, stopping bleeding, reducing swelling and relieving pain, and is suitable for treating various bleeding symptoms and traumatic injuries. Due to its various pharmacological effects, the extract is widely used in the fields of medicine and skin care products.

Specification

Health enefits

Antioxidant

Panax notoginseng extract is rich in polyphenol compounds, which have powerful antioxidant effects, can scavenge free radicals, and protect the skin from oxidative damage. Long-term use of Panax notoginseng extract can slow down the skin aging process, keep the skin young, and prevent the formation of spots and other skin problems.

Anti-inflammatory and anti-fatigue

It has a certain anti-inflammatory effect and can reduce inflammatory reactions; at the same time, it also has anti-fatigue effects, which helps to relieve physical fatigue and restore physical strength.

Immunomodulation

It can regulate the body's immune function, enhance the body's resistance, and help prevent and treat some immune-related diseases.

Promote blood circulation

The saponin components in the extract can dilate blood vessels and reduce blood viscosity, thereby promoting blood circulation. This helps to improve the oxygen and nutrient supply to local tissues and relieve skin problems caused by poor blood circulation, such as dull skin or ischemic plaques.

Improve skin microcirculation

The flavonoids contained have the effect of relaxing vascular smooth muscles, which can increase capillary permeability and blood flow, thereby improving skin microcirculation. This is beneficial to improve the metabolism level of skin cells, promote skin repair and regeneration, and has a positive effect on improving skin texture and reducing wrinkles.

Dispersing blood stasis and stopping bleeding

It has the effect of dispersing blood stasis and stopping bleeding, and can be used to treat various bleeding symptoms such as hemoptysis, hematemesis, epistaxis, blood in stool, metrorrhagia, and traumatic bleeding. Its hemostatic effect is unique, it can both stop bleeding and remove blood stasis, and has the characteristics of "stopping bleeding without leaving blood stasis, and removing blood stasis without hurting the body".

Reducing swelling and relieving pain

It can promote blood circulation and reduce swelling, and has strong analgesic power. It is suitable for the treatment of various symptoms of blood stasis, traumatic injuries, tendon fractures, blood stasis, swelling and pain, and chest and abdominal pain caused by blood stasis. Its effect of reducing swelling and relieving pain helps relieve patients' pain and discomfort.

Improve coronary microcirculation

It can increase coronary blood flow, reduce myocardial oxygen consumption, help improve and strengthen coronary microcirculation, and have a certain auxiliary therapeutic effect on cardiovascular diseases such as angina pectoris.

Anti-inflammatory mechanism

Inhibit cytokine production

Cytokines released during neuroinflammation, such as TNF-α and IL-1, can induce neuronal apoptosis. Saponins in Panax notoginseng extract have anti-inflammatory effects and can inhibit cytokine production and signal transduction, thereby reducing neuroinflammation damage to neurons.

Scavenging free radicals and reducing inflammatory response

Panax notoginseng extract is rich in phenolic compounds and saponins, which have strong antioxidant activity and can scavenge free radicals. The reduction of free radicals can reduce oxidative stress, which is often associated with inflammatory response. Reducing oxidative stress helps to inhibit the development of inflammatory response. At the same time, Panax notoginseng extract can inhibit lipid peroxidation and reduce the generation of oxidative damage products, thereby protecting the integrity of cell membranes, which also helps to reduce inflammatory response.

Regulate apoptosis signaling pathways to reduce inflammation

Panax notoginseng extract can regulate the expression of Bcl-2 family proteins, increase the expression of anti-apoptotic protein Bcl-2, and inhibit the expression of pro-apoptotic proteins Bax and Bak. Cell apoptosis is closely related to inflammatory response, and by regulating the expression of apoptosis-related proteins, it can indirectly affect the inflammatory response. In addition, Panax notoginseng extract can activate the PI3K/Akt signaling pathway, promote the survival and proliferation of neurons, and the activation of this signaling pathway also helps to reduce the damage to cells caused by inflammatory responses.

How to promote blood circulation?

Notoginseng saponins have multiple effects to promote blood circulation. It can inhibit platelet aggregation and prevent platelets in the blood from excessively adhering to form thrombi, thereby maintaining the fluidity of blood, which helps blood circulation proceed smoothly. For example, some studies have found that notoginseng saponins can regulate the function of platelets, making it less likely to aggregate on the blood vessel wall, reducing the risk of thrombosis, and promoting the normal flow of blood in the blood vessels.

Notoginseng saponins can also dilate blood vessels, especially coronary arteries. When the coronary arteries dilate, it can increase the blood flow of the coronary arteries and provide more oxygen and nutrients to the heart, which has a positive effect on the entire blood circulation system. It is like providing a wider "oil road" for the heart, the "engine", to ensure the normal function of the heart and promote blood circulation.

In addition to notoginseng saponins, ingredients such as flavonoids in notoginseng extracts also help promote blood circulation. Flavonoids have antioxidant properties, which can reduce the damage of vascular endothelial cells to free radicals and maintain the normal function of vascular endothelium. Normal endothelial function is very important for regulating the relaxation and contraction of blood vessels, which can ensure the normal flow of blood in blood vessels and avoid blood vessel stenosis or blockage affecting blood circulation.

It can reduce the viscosity of blood. Excessive blood viscosity will increase the resistance to blood flow and affect the speed of blood circulation. Panax notoginseng can make the blood thinner by adjusting the components in the blood, such as lowering blood lipids, etc., reducing the resistance to blood flow and allowing blood to circulate more smoothly in the blood vessels. For example, it can reduce the cholesterol and triglyceride content in the blood, reduce the lipid components in the blood, thereby reducing blood viscosity and promoting blood circulation.

In terms of microcirculation, notoginseng glycosides and notoginseng saponins can promote blood flow in microcirculation. Microcirculation refers to the blood circulation between arterioles and venules, which is critical for the exchange of nutrients and the discharge of metabolic waste in various tissues and organs of the body. When microcirculation is improved, blood supply and material exchange in various parts of the body can be carried out more effectively, thereby promoting overall blood circulation.

Application

Health products

It can be developed into different types of health products for different health needs. For example, it can be used to assist in the treatment of cardiovascular and cerebrovascular diseases, improve immunity, improve memory, etc.

Cosmetics

Anti-inflammatory and soothing skin, reducing allergic reactions: saponins, triterpenes, flavonoids and other substances in Panax notoginseng extract have the ability to resist inflammation, antioxidant and repair skin, and have good effects in soothing skin and reducing allergic reactions. It is suitable for skin care products for people with sensitive skin.

Anti-aging: It has a strong antioxidant effect and can effectively remove oxygen free radicals, DPPH free radicals, and ABTS free radicals.

Whitening and freckle removal: It also has certain effects in whitening and freckle removal, which helps to improve skin color.

Promote collagen synthesis: The Panax notoginseng saponin B contained can promote the synthesis of collagen, effectively help the skin restore elasticity, reduce wrinkles and sagging, and keep the skin healthy and young.

Medicine

Treatment of various bleeding diseases: It has the effect of dispersing blood stasis and stopping bleeding. It can be used for various bleeding symptoms inside and outside the human body, such as hemoptysis, hematemesis, epistaxis, blood in stool, hematuria, traumatic bleeding, etc. It can be used regardless of whether there is blood stasis, especially for those with blood stasis. For example, some hemostatic Chinese patent medicines may contain Panax notoginseng extract ingredients.

Treatment of traumatic injuries and blood stasis and swelling: It tastes sweet and slightly bitter, is warm in nature, and belongs to the liver and stomach meridians. It has strong blood circulation and swelling, and analgesic power. It can treat various symptoms of blood stasis, traumatic injuries, or tendon fractures, blood stasis and swelling, blood stasis and chest and abdominal pain. In drugs such as Yunnan Baiyao used for the treatment of traumatic injuries, Panax notoginseng extract is one of the main ingredients.

Medications for cardiovascular and cerebrovascular diseases: It has the effects of anti-thrombosis, accelerating blood flow, improving microcirculation, and anti-cerebral ischemia. It is often used in cardiovascular and cerebrovascular drugs, such as Jiuxin Pills and Xinmaitong Tablets.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Panax notoginseng extract and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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