Gynostemma Extract Powder

What is Gynostemma Extract?

Gynostemma Extract Powder is composed of more than 50 kinds of Gynostemma saponins isolated from the plant Gynostemma pentaphyllum. Like ginsenosides, they belong to the tetracyclic triterpenoid genus saponins. According to traditional Chinese medicine, Gynostemma pentaphyllum is bitter in taste and cold in nature, and has the functions of clearing away heat and detoxifying, replenishing qi, relieving cough, and eliminating phlegm.

More than 50 kinds of gypenosides have been isolated from Gynostemma pentaphyllum. Like ginsenosides, they belong to the tetracyclic triterpenoid genus saponins. Among them, gypenosides III, IV, VII, and XII are the same substance as ginsenosides Rb1, Rb3, Rd, and F2 respectively. , gypenosin V-AH is the same as ginsenoside Rg3, and ginsenoside I is enzymatically decomposed into ginsenoside K. Pharmacological and clinical analysis results in ginsenoside K.

Chemical composition

Gynostemma pentaphyllum extract powder mainly contains saponins, with the highest content in leaves, followed by stems and aboveground parts. Its basic structure is a dammarane-type tetracyclic triterpene. It also includes flavonoid glycosides, sugars, sterols, organic acids, pigments, cellulose, plant protein, starch, etc.

1.Saponins

The saponin content in Gynostemma pentaphyllum is an important indicator for evaluating the quality of Gynostemma pentaphyllum, and there are hundreds of them. It is mainly distributed in the assimilation tissues of vegetative organs and phloem parenchyma cells. The content varies depending on the variety, environment and other factors, and is generally 2% to 8% of dry weight. Four of the total saponins of Gynostemma pentaphyllum are ginsenosides. Among them, gypenosides III, IV, and VIII are ginsenosides Rb1, Rb3, and Rd, respectively, as well as panaxadiol, 2α, 19-dihydroxy-12deoxypanaxadiol, and gypenoside A. The total saponin content is 3 times that of ginseng. Gynostemma pentaphyllum is the only plant besides Araliaceae and Ginseng that contains ginseng saponin, and the content of ginseng saponin in excellent plants is even higher than that of ginseng.

2. Flavonoids

More than 10 kinds of flavonoids, including SH-4, Phytolactin, Phytolactin, rutin, Gypenospermide 2A, malonate, malonic acid, and trigonate.

3.Polysaccharides

The stems and leaves of Gynostemma pentaphyllum contain fructose, glucose, galactose and oligosaccharides, and the hydrolyzate contains rhamnose, xylose, arabinose, glucose and galactose.

4.Others

Gynostemma pentaphyllum also contains 18 kinds of amino acids, sugars, cellulose, sterols, pigments, 23 kinds of trace elements and other ingredients.

What are the benefits?

1. Immunomodulatory effect

(1) Spleen-increasing effect: Gynostemma pentaphyllum extract powder can increase the spleen weight of mice. Lymphocytes increased around the central splenic artery, and the T lymphocyte transformation rate was enhanced. The number of monocytes proliferated and phagocytosis was active.

(2) Whitening effect Gynostemma pentaphyllum saponin can increase the number of peripheral blood leukocytes, enhance the phagocytic ability of leukocytes, and has an increasing effect on leukopenia caused by CTX.

(3) Phagocytosis Gynostemma pentaphylla polysaccharide can significantly enhance the phagocytosis of peritoneal macrophages.

(4) Regulation of DNA. Gynostemma pentaphyllum saponins can promote lymphocyte DNA synthesis in small doses, but have the opposite inhibitory effect in large doses.

2. Anti-aging effect

Gynostemma pentaphyllum total saponins can significantly extend the average life span of fruit flies, significantly increase the SOD activity in the brains and livers of house flies and mice, and significantly reduce the MDA content. Gynostemma pentaphyllum saponin can reduce the content of peroxidized lipids in the serum, heart, brain, and liver of aged rats, as well as the content of brain lipofuscin. Gynostemma pentaphyllum polysaccharide also has the effect of delaying aging.

3. Protective effect against myocardial infarction and myocardial ischemia

Both in vivo and in vitro experiments have confirmed that injection of gypenosin has a significant protective effect on myocardial infarction and myocardial ischemia-reperfusion injury. Reduce the scope of myocardial infarction, inhibit the increase in free fatty acids in blood after myocardial infarction, reduce the MDA content in rat myocardium, protect myocardial SOD activity, and inhibit the increase in lactate dehydrogenase in serum.

4. Anti-platelet aggregation effect

Animal in vivo and in vitro experiments have shown that GP has a significant inhibitory effect on platelet aggregation induced by ADP, arachidonic acid and collagen. It can also significantly inhibit the release of platelet 5-HT induced by collagen and increase the cAMP level in platelet suspension. GP has an inhibitory effect on both arterial thrombosis and venous thrombosis. The mechanism may be similar to that of aspirin.

5. Enhance physical strength and anti-fatigue effects

Gynostemma Extract Powder aqueous extract, saponins and total glucosides have been experimentally proven to prolong the swimming time, pole climbing time and weight swimming time of mice. Gynostemma pentaphylla extract administered intragastrically for 14 consecutive days at 200 mg/kg can maintain high blood sugar levels and reduce muscle glycogen loss in rats that swim for long periods of time. This may be an important reason why Gynostemma pentaphyllum can resist fatigue.

6. Hypolipidemic effect

0.25% to 0.5% Gynostemma pentaphyllum aqueous extract has a significant reduction effect on total cholesterol and triglyceride in rat serum and liver. Gynostemma pentaphyllum total saponins can inhibit the increase of serum total cholesterol and triglyceride in hypercholesterolemia mice, and reduce the serum cholesterol, triglyceride and low-density lipoprotein in hyperlipidemia quail, and have diffuse effects on the liver of hyperlipidemia quail. It has a protective effect against lipidosis and atherosclerosis formation.

7. Hypoglycemic effect

Alloxan diabetic mice were given Gynostemma pentaphyllum extract by intragastric administration for 3 consecutive days, which had obvious hypoglycemic effects.

8. Enhance sexual function

Intragastric administration of Gynostemma pentaphyllum extract can significantly increase the weight of the testes and prostate of male mice and the uterus of female mice compared with the control group, indicating that Gynostemma pentaphyllum has male and female hormone-like effects.

9. Hepatoprotective effect

(1) Prevention and treatment of acute liver injury Gynostemma pentaphyllum saponin has an intervention and protective effect on liver injury caused by alcohol. It can reduce the degree of fatty degeneration of liver tissue, prevent lipid peroxidation damage to liver cell membranes and subcellular structures caused by oxygen free radicals, and protect liver cell membranes. Integrity, improve liver microcirculation, increase blood flow, promote the excretion of toxins, thereby reducing liver damage.

(2) Anti-hepatic fibrosis effect Gynostemma pentaphyllum saponin can significantly reduce aspartate aminotransferase and alanine aminotransferase that are increased in liver damage, and can increase the albumin/globulin ratio; reduce collagen, and pathological observation shows that liver Collagen becomes thinner, confirming that Gynostemma pentaphyllum saponins have liver-protecting and anti-hepatic fibrosis effects.

(3) Anti-non-alcoholic fatty liver disease Gynostemma pentaphyllum and its extracts can significantly reduce liver and serum lipids, and have a therapeutic effect on non-alcoholic fatty liver disease.

(4) Gynostemma pentaphyllum total saponins 50 mg/kg can significantly inhibit the increase in serum aminotransferase activity caused by carbon tetrachloride. Reduce the content of peroxidized lipids in liver tissue and reduce damage to the liver.

10.Others

(1) Effect of increasing coronary artery flow Gynostemma pentaphylla extract can increase the coronary artery flow of isolated rabbit heart and slow down the heart rate; intravenous injection has antihypertensive effect.

(2) Gynostemma pentaphyllum extract has sedative, analgesic and hypnotic effects.

(3) Gynostemma pentaphyllum saponins have antioxidant and anti-damage effects, protect the skin, and promote ulcer healing.

Application direction

Gynostemma pentaphyllum tastes very bitter and is not suitable for medicinal diet and dietary therapy, but it can be used as a health care product.

1.Health products and food

Gynostemma Extract Powder can also be used to make medicinal wine, capsules and granules. It is used to strengthen the body, protect the liver, and prevent and treat diseases. Gynostemma Pentaphyllum Medicinal Wine: A compound recipe of 9g Gynostemma pentaphyllum, 9g raw sun-dried ginseng, 30g Ganoderma lucidum, 9g licorice, and 30g red dates. A small amount of rock sugar, honey and other sweeteners can be added to correct the taste. The elderly take it for a long time to strengthen their body and resist aging. Gynostemma pentaphyllum health tea, Gynostemma pentaphylla beverage, Gynostemma pentaphylla beer, Gynostemma pentaphyllum sake, Gynostemma pentaphyllum food additives, etc. have been developed and launched.

2. Feed and additives

In terms of animal husbandry, with the development and growth of animal husbandry and breeding industry, the issues of medicines and feed additives have attracted people's attention. Gynostemma pentaphyllum medicines and food additives not only contain a variety of trace elements, but also have stomachic, anti-inflammatory, antibacterial, and health-enhancing properties. The function of immunity can regulate the nervous system and endocrine activities, help increase the appetite of poultry, livestock, fish and shrimp, etc., and improve feed utilization. It can be seen that Gynostemma pentaphyllum, as a plant-based feed additive, has good development prospects for improving the resistance of livestock and poultry and preventing and treating infectious diseases.

3. Cosmetics

Because of its anti-aging, hair loss and beauty effects, it has high development value in the cosmetics industry. For example, by mixing Gynostemma pentaphylla crude saponin with stearic acid, lotions, cosmetic creams, soaps, etc. can be prepared. Although the application research of Gynostemma pentaphyllum has gradually become a hot spot, many effects of Gynostemma pentaphyllum have not been fully utilized, so Gynostemma pentaphyllum has huge development value and potential.

Gynostemma pentaphyllum extract powder supplier

Yuantai Organic Bio is committed to providing customers with the highest-quality bulk Gynostemma Extract Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

Package & Shipment

Our Company and Factory