Diammonium glycyrrhizinate Powder

What is Diammonium Glycyrrhizinate?
Diammonium glycyrrhizinate is the third generation extract of the effective ingredient of Chinese medicinal licorice, which has strong anti-inflammatory, liver cell membrane protection and liver function improvement effects. It is the 18α body of glycyrrhizic acid, and its lipophilicity is greater than that of the β body. Monoammonium glycyrrhizinate is easy to bind to receptor proteins and target cell receptors of steroid hormones in the body.
This product has strong anti-inflammatory, liver cell membrane protection and liver function improvement effects. It has a dose-dependent preventive and therapeutic effect on liver damage caused by a variety of hepatotoxic agents; it can significantly improve the survival rate and improve liver function for chronic liver damage caused by complex pathogenic factors. Experiments have shown that this product can significantly prevent the increase of serum alanine aminotransferase (ALT) caused by galactosamine, carbon tetrachloride and thioacetamide, and improve damaged liver tissue. Liver tissue sections show that this product can counteract the damage to liver cell mitochondria and nucleoli caused by galactosamine, increase the content of liver glycogen and nucleic acid, reduce liver cell necrosis, and accelerate liver cell recovery.
Efficacy

1. Antioxidant ability: mainly attributed to the glycyrrhizic acid root and ammonium group in its structure. Glycyrrhizic acid root is a triterpenoid compound with reducing and free radical quenching capabilities. It can react with active oxygen, free radicals and peroxides, converting them into harmless molecules, thereby terminating the oxidation reaction chain and protecting cells from oxidative damage. Studies have shown that it can effectively scavenge superoxide anion radicals, hydroxyl radicals and hydrogen peroxide, thereby reducing the level of intracellular oxidative stress. In addition, it can react with lipid peroxides and protein carbonyl compounds to prevent oxidative damage to lipids and proteins.
The ammonium group has redox activity and can participate in electron transfer reactions. It can react with peroxides and free radicals to reduce them to harmless molecules. Its presence can also enhance the antioxidant capacity of glycyrrhizic acid. This product has higher antioxidant activity than glycyrrhizic acid, which may be due to the synergistic effect of the ammonium group.
Its antioxidant capacity is affected by many factors, including:
Concentration: The antioxidant activity increases with increasing concentration.
PH: Under neutral or weakly alkaline conditions, the antioxidant activity is higher.
Temperature: Increased temperature will reduce the antioxidant activity.
Metal ions: It will react with certain metal ions, affecting its antioxidant capacity.
Application prospects
Food industry: It can be used as an antioxidant to delay the oxidative deterioration of food and extend the shelf life.
Cosmetics industry: It can be used as an antioxidant and anti-aging agent, added to skin care products to protect the skin from free radical damage and improve skin health.
Pharmaceutical industry: It has antioxidant and anti-inflammatory effects and can be used to treat various diseases related to oxidative stress, such as cardiovascular disease, neurodegenerative diseases, etc.
2. Anti-inflammatory effect: It mainly inhibits the activity of inflammatory cytokines cyclooxygenase and lipoxygenase, thereby reducing the production of inflammatory mediators such as prostatitis and leukotrienes. It can stabilize cell membranes, prevent the release of inflammatory factors, and inhibit the production of proinflammatory cytokines.
3. Immunomodulatory effect: It can regulate cell function by inhibiting cell proliferation and cytokine production. It can affect the immune response by regulating the maturation and antigen presentation ability of dendritic cells. It can inhibit the secretion of proinflammatory cytokines by dendritic cells and promote the production of anti-inflammatory cytokines. It can inhibit the production of proinflammatory cytokines by macrophages and promote the production of anti-inflammatory cytokines. It also inhibits the phagocytic activity of macrophages.
4. Anti-aging effect:It can promote the proliferation and differentiation of epidermal cells and improve skin thickness and elasticity by activating epidermal growth factor receptors. In addition, it can inhibit the activity of matrix metalloproteinases, thereby reducing the degradation of collagen and elastin, keeping the skin firm and smooth.
It can stimulate the synthesis of the main collagen in the skin responsible for providing structure and elasticity, enhance the connection between the epidermis and dermis, help maintain the integrity of the skin structure, reduce the formation of wrinkles and fine lines, and play a role by regulating the expression of collagen genes and activating fibroblasts, thereby enhancing the elasticity of the skin.
It can scavenge free radicals, reduce oxidative damage, effectively inhibit lipid peroxidation, and protect cell membranes from damage, thereby delaying skin aging.
It can regulate the production and degradation of dermal matrix molecules, including hyaluronic acid, elastin, and glycosaminoglycans. It restores the fullness and radiance of the skin by increasing the thickness and density of the dermal matrix.
Formulation
Capusle Formulation

Tablet Formulation

Solid Drink Formula

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Diammonium Glycyrrhizinate and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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