Bulk Rutin Powder
CAS:153-18-4
Molecular formula: C27H30O16
Molecular weight: 610.52
EINECS:205-814-1
Melting point: 195 °C (dec.)(lit.)
Shipping speed:1-3 days
Inventory:In stock
Certificates:HACCP, HALAL, KOSHER, ISO9001, ISO22000, FDA
MOQ:25KG
Package:25Kg/barrel
Sales group:not for individual customers
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Product Introduction
What is rutin?
Bulk Rutin Powder, also known as rutin and vitamin P, has a molecular formula of C27H30O16. It is a natural flavonoid glycoside and belongs to the flavonol glycosides widely present in plants. The two glycosides are glucose and rhamnose. Appearance: light yellow or light green crystalline powder. Soluble in pyridine, formyl and alkali, slightly soluble in ethanol, acetone and ethyl acetate, almost insoluble in chloroform, ether, benzene, carbon disulfide and petroleum ether. It has anti-inflammatory, antioxidant, anti-allergic, anti-viral and other effects.
Rutin Powder is the rutin glycoside of the flavonol compound quercetin. It is a flavonoid compound extracted from plants. It is found in rue, tartary buckwheat, sophora buds, catalpa leaves, tomato stems, leaves and seed shells. It is about to bloom. Current dry buckwheat contains about 3%, and jujube, hawthorn, ginkgo, wolfberry, motherwort, bupleurum, prunella vulgaris, aloe, Gynostemma pentaphyllum, etc. all contain rutin. In the flower buds of the legume Sophora japonica L., the content can reach more than 20%, and it is the main raw material for extracting rutin in my country's pharmaceutical industry. Rutin can be decomposed by adding water when encountering strong acidity and alkalinity. The color is unstable in alkaline foods and has antioxidant ability. In ethanol, it can improve the light resistance of pigment preparations and prevent the gradual disappearance or change of fragrance. Combined with vitamin E, etc., it can improve its antioxidant capacity.
The inhibitory effect of rutin on lipid peroxidation is related to its enhancement of SOD activity in the body and promotion of oxygen free radical scavenging. Xia Weimu and others found that rutin has a strong scavenging effect on O2-, and the scavenging efficiency can reach more than 96%. As a chelating agent for Fe2+, rutin can inhibit the Fenton reaction and the chain reaction of lipid peroxidation and has obvious anti-lipid peroxidation effect. A variety of rutin health foods have been developed abroad. Sophora rice has a strong antioxidant effect on edible oil. The free radical scavenging rate of Sophora japonica extract can reach 40% to 70%. It can be used as a new type of edible oil and fat-containing food additive with health care functions. It can also be used in cold drinks, beverages, pastries, and processed meat products. , processed aquatic products. Tartary buckwheat rutin health factor has the effects of lowering blood lipids, lowering blood pressure, lowering urine sugar, and losing weight and keeping fit. It has been developed into delicious and convenient snacks (tartary buckwheat tea, tartary buckwheat rice, tartary buckwheat noodles, etc.). Hydrolyze rutin with 2% dilute H2SO4 for 1 hour, filter and collect the precipitate after cooling, wash and dry, and the crude product can be recrystallized from ethanol to obtain fine quercetin. If other flavonoids such as quercetin are mixed with α-tocopherol or catechin, additive effects can be shown.
What are the benefits?
Anti-free radical effect
Oxygen molecules are reduced in the form of single electrons in cell metabolism. The O ions produced by the single electron reduction of oxygen molecules then produce H2O2 and extremely toxic ·OH free radicals in the body, thus affecting the tenderness and smoothness of the skin and even accelerating the growth of the skin. The degree of aging, and adding rutin to the product can obviously remove the reactive oxygen species produced by cells. Rutin is a flavonoid compound and a strong antioxidant that scavenges free radicals. It can terminate the chain reaction of free radicals, inhibit the peroxidation of polyunsaturated fatty acids on biological membranes, remove lipid peroxidation products, and protect biological membranes and The integrity of subcellular structures plays an important role in the body.
Anti-lipid peroxidation
Lipid peroxidation refers to a series of oxidation processes caused by active oxygen free radicals attacking polyunsaturated fatty acids in biological membranes. Through the measurement and analysis of rat SOD activity, free radical lipid peroxidation product MDA content and large liver lipofuscin content, it was found that rutin has an inhibitory effect on lipid peroxidation in castrated rats. Decreased antioxidant capacity of the rat antioxidant system. Rutin can counteract the decrease in antioxidant capacity caused by the decrease in endogenous estrogen and has antioxidant effects. High-density lipoprotein (HDL) has anti-atherosclerotic effects. However, HDL, like low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL), can also be oxidatively modified in vitro. Once HDL is oxidized and modified into Ox-HDL, it has an atherogenic effect. Meng Fang et al. used Cu2+-mediated oxidative modification in vitro to explore the effect of rutin on the oxidative modification of HDL. The conclusion shows that rutin can significantly inhibit the oxidative modification of HDL.
Antagonizes the effects of platelet activating factor
The pathogenesis of many cardiovascular and cerebrovascular diseases, such as thrombosis, atherosclerosis, inflammatory response, and ischemia-reperfusion free radical damage, are closely related to the mediation of platelet activating factor (PAF). Therefore, antagonizing the effect of PAF is beneficial to It is currently an important way to alleviate ischemic cardiovascular and cerebrovascular diseases. Experiments show that rutin can concentration-dependently antagonize the specific binding of PAF to rabbit platelet membrane receptors, inhibit PAF-mediated rabbit platelet adhesion and increase the free Ca2+ concentration in PMNs, indicating that the mechanism of rutin's anti-PAF action is through inhibiting PAF The receptor is activated, thereby blocking the PAF-induced response, thus playing a cardiovascular protective role. The results show that rutin is a PAF receptor antagonist.
Anti-acute pancreatitis
Bulk Rutin Powder can effectively prevent the occurrence of hypocalcemia and reduce the Ca2+ concentration in pancreatic tissue. Studies have found that rutin can increase the content of phospholipase A2 (PLA2) in rat pancreatic tissue, suggesting that rutin may have an inhibitory effect on the release and activation of PLA2 in pancreatic tissue; rutin can effectively prevent the occurrence of hypocalcemia in AP rats, which may It reduces the pathophysiological damage to AP by preventing Ca2+ influx and reducing Ca2+ overload in pancreatic tissue cells.
Promote heart health
When it comes to heart health, recent research shows that Rutin Powder helps maintain blood vessel elasticity, reduce blood vessel fragility, reduce capillary permeability and prevent complications from high blood pressure.
Relieve arthritis symptoms
Animal studies show that this antioxidant has the ability to suppress acute and chronic inflammation. This makes it a potential natural treatment for arthritis. Russian researchers have found that rutin can reduce the excessive production of free radicals in rheumatoid arthritis. They concluded that it could be considered a useful adjunct agent.
Prevent metabolic diseases
Research shows that rutin may protect us from the effects of metabolic syndrome as we age. Studies involving aged rats found that flavonoids suppressed increases in fasting blood sugar, insulin levels and blood pressure.
Rutin administration improved aging-related metabolic dysfunction in rats by reducing inflammation, lipid accumulation, oxidative stress, and mitochondrial disease, which is caused by mitochondrial failure found in nearly every cell in the human body.
Protect brain health
Research shows that rutin has protective effects against brain injury and age-related injuries. It also helps promote brain health due to its anti-inflammatory and antioxidant properties.
In 2018, research published in Oxidative Medicine and Cellular Longevity showed that this bioflavonoid may serve as a promising neuroprotective compound for the treatment of diseases including Alzheimer's, Parkinson's and Huntington's diseases of neurodegenerative diseases. Researchers believe it protects brain health by reducing pro-inflammatory cytokines, increasing antioxidant enzyme activity and restoring the activity of mitochondrial complex enzymes within cells.
Improve circulation
In traditional medicine, rutin is known for its ability to strengthen blood vessels and improve blood circulation. It is used to reduce the appearance of varicose veins, relieve hemorrhoids and prevent hemorrhagic strokes caused by ruptured veins or arteries.
According to a review published in the International Journal of Molecular Sciences, rutin preparations were reported to significantly reduce leg swelling, relieve leg pain, and reduce leg cramping, heaviness, and itching. This may be due to its ability to reduce inflammation and improve blood circulation.
Application direction
1. Food coloring (like lemon yellow); antioxidant; nutritional supplement. Mainly used for cold drinks, beverages, pastries, meat processed products, aquatic product processed products, etc.
2. Vitamin drugs. It has the effect of reducing capillary permeability and fragility, maintaining and restoring the normal elasticity of capillaries. It is used to prevent and treat hypertensive cerebral hemorrhage, diabetic retinal hemorrhage and hemorrhagic purpura. It is also used as a food antioxidant and pigment.
3. It has anti-inflammatory effect; vitamin P-like effect, it can maintain blood vessel resistance, reduce its permeability, reduce fragility, etc., and has a lipid-removing effect on fat-infiltrated liver. The lipid-removing effect is more obvious when combined with glutathione. ; Antiviral effect and inhibition of aldose reductase.
Rutin Powder supplier
Yuantai Organic Bio is committed to providing customers with the highest-quality Bulk Rutin Powder and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.