Amygdalin

What Is Amygdalin?

Amygdalin is a cyanogenic glycoside compound found in bitter almonds, also known as amygdalin and vitamin B17. It is mainly found in the seeds of plants of the Rosaceae family, such as bitter almonds, peaches, cherries, plums, etc., especially in wild apricots, where the content can reach 2%-3%. It is the main active ingredient in bitter almonds and has multiple pharmacological effects. It is an effective ingredient for treating respiratory diseases. It slowly releases hydrocyanic acid in the body to paralyze and inhibit the respiratory central system, thereby playing a role in relieving asthma. It is widely used in traditional Chinese medicine to treat coughs, etc.

Product Details Tables

Features

1. It is a β-glycoside composed of gentiobiose and amygdalin, belonging to the cyanogenic glycosides.
2. It has a melting point between 223℃ and 226℃, is easily soluble in water and alcohol, and is almost insoluble in ether.
3. It is easily hydrolyzed by acids and enzymes. The aglycone α-hydroxyphenylacetonitrile obtained after hydrolysis is unstable and easily decomposes to form benzaldehyde and hydrocyanic acid.

What Are The Benefits?

Anti-mutation

It can reduce the number of micronucleated polychromatic erythrocytes caused by certain drugs.

Antitussive and antiasthmatic

Amygdalin is hydrolyzed by intestinal microbial enzymes or amygdalin contained in bitter almonds in the body to produce trace amounts of hydrocyanic acid and benzaldehyde, which have an inhibitory effect on the respiratory center, thereby achieving the effect of antitussive and antiasthmatic.

Affecting the digestive system

While hydrocyanic acid is decomposed by enzymes, benzaldehyde is also produced, which can inhibit the activity of pepsin, thereby affecting the digestive function.

Beauty

It contains fatty oils that can soften the stratum corneum of the skin, moisturize the skin, protect nerve endings, blood vessels and tissues and organs, and inhibit bacteria. In addition, HCN generated by enzyme hydrolysis can inhibit active tyrosinase in the body, eliminate pigmentation, freckles, dark spots, etc., thereby achieving a beauty effect.

Hypoglycemic

It has the effect of preventing and treating diabetes caused by the anti-tumor drug alloxan, and can specifically inhibit the increase in blood sugar caused by alloxan.

Lowering blood lipids

It can significantly reduce the blood lipid levels of patients with hyperlipidemia, and the monounsaturated fatty acids in it can help lower patients' slightly elevated blood lipids.

Application

Food

It can be used as a food additive to produce almond milk, almond biscuits and other foods, which can not only increase the flavor of the food, but also exert its health effects.

Health products

It is made into various health products and dietary supplements to enhance immunity, anti-oxidation, prevent tumors, etc., to meet people's pursuit of health.

Cosmetics

It has antioxidant, anti-inflammatory, whitening and moisturizing effects, and can be used to develop cosmetics with anti-aging, moisturizing, whitening and other effects.

Medicine

It is an important ingredient in traditional Chinese medicine and is often used to treat symptoms such as cough, asthma, and constipation.

Production Method

Water extraction method

Use almonds or raw peach kernels as raw materials, directly extract with hot water, the extraction time is about 20 minutes, the solid-liquid ratio is 1:10, the soaking time is 30 minutes, and the extraction is twice. The extraction rate of this method is close to 3.2%.

Alcohol extraction method

Use apricot pollen or bitter almonds as raw materials, use anhydrous ethanol for extraction, the solid-liquid ratio is 1:7, ultrasonic for 20 minutes, and extract for 12 hours. The extraction rate of this method is 6.1%.

It can be extracted by adding 6 times 95% ethanol for 1 hour, a total of 2 times, and then recrystallized with anhydrous ethanol. The extraction rate of this method is 92.47% and the transfer rate is 45.92%.

Macroporous adsorption resin separation and purification method

Use macroporous adsorption resins such as lsa-30 or hz801, which are suitable for adsorption and separation of amygdalin. The adsorption conditions include room temperature extract pH 6-9, adsorption flow rate 1-2 ml/min; elution conditions are 40°C, eluent 60% ethanol (pH6 or pH8), elution flow rate 1-2 ml/min. The purity of amygdalin in this method is 93.6%.

Ultrasonic extraction method

Using mountain almond as raw material, solid-liquid ratio is 1:5, ethanol concentration is 80%, extraction temperature is 70°C, extraction time is 40 minutes, and ultrasonic power is 64 W.

Microwave extraction method

Using bitter almond as raw material, anhydrous ethanol as solvent, solid-liquid ratio is 1:6, extraction temperature is 75°C, extraction time is 15 minutes each time, and microwave power is 500 W.

Formulation Of Amygdalin

Capusle Formulation

Tablet Formulation

Solid Drink Formula

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Amygdalin and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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