Bulk Vitamin D3 Powder
EINECS: 200-673-2
Molecular Formula: C27H44O
Molecular Weight: 384.64
Melting Point: 83-86 °C (lit.)
Boiling Point: 451.27°C
Package:1kg/Bag,25kg/Drum
Storage Conditions: Cool And Dry Place
Shelf Life: 24 months
Shipping Speed:1-3 days
Testing Method: HPLC
Certifications: ISO9001,ISO22000,Kosher,Halal,HACCP
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Product Introduction
Do you really know about vitamin D3?
Bulk Vitamin D3 powder, also known as cholecalciferol, is a member of the vitamin D family. It has been proven to be the true active form of vitamin D in the body and is considered to be a hormone precursor that acts on calcium and phosphorus metabolism. It is the fat-soluble vitamin with the highest biological metabolism rate in the vitamin D family and is known as the "anti-rickets vitamin" and the "sunshine vitamin".
There are at least 10 known vitamin Ds, but the most important ones are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Vitamin D3 belongs to cholecalciferol, a fat-soluble vitamin that promotes intestinal absorption of calcium and phosphorus and plays an important role in the formation of bones and teeth.
If the body lacks vitamin D3, calcium absorption will be affected, which is why vitamin D3 is also needed for calcium supplementation. At the same time, this is why newborns need to supplement vitamin D3: "Vitamin D3, as a 'carrier' of calcium, can also prevent the occurrence of rickets."
Why are the benefits?
Regulate immune function:It has immunomodulatory effects and is a good selective immunomodulator. It has certain effects in preventing and treating autoimmune encephalomyelitis, rheumatoid arthritis, multiple sclerosis, type 1 diabetes and inflammatory bowel disease.
Promote the absorption of calcium by the small intestine: It can promote the absorption of calcium and phosphorus by the intestinal wall, thereby reducing the concentration of parathyroid hormone, effectively alleviating the symptoms of bone pain, and promoting bone function.
Increase the elasticity of blood vessels: It can improve arterial health by blocking a hormone that increases vasoconstriction. In addition, it also helps to reduce inflammation, which is related to arteriosclerosis.
Regulate the development of the placenta: It can regulate the development and function of the placenta, so that pregnant women maintain adequate content, which can prevent miscarriage, preeclampsia and premature birth.
Promote calcium and phosphorus absorption: It can promote the body's absorption of calcium and phosphorus, so that the levels of calcium and phosphorus in plasma remain in a balanced state. Because it promotes the absorption of calcium and phosphorus, it can ensure the normal growth of the body and bone calcification, and ensure the health of teeth. Therefore, it is crucial in proper calcium and phosphorus metabolism.
Anti-rickets: It will be lacking when there is insufficient intake, insufficient sunlight or malabsorption. Its main function is to regulate calcium metabolism, promote calcium absorption and bone tissue formation. Therefore, when it is lacking, children will suffer from rickets, which is similar to calcium deficiency, with baldness on the back of the head, square head, pigeon chest, "O" or "X" legs. Adults will experience osteomalacia, leading to symptoms such as bone hyperplasia and osteoporosis.
Vitamin D3 combined with Lactobacillus rhamnosus GG/p40 alleviates colitis in mice by promoting intestinal epithelial vitamin D receptor expression and cell proliferation
In the in vivo experiment, dextran sulfate sodium (DSS) colitis models were established in Vdr+/+ and Vdr-/- mice, and VitD3, LGG, and p40 were given alone or in combination for 7-14 days. The body weight, disease activity index (DAI), colon length, colon tissue pathological injury score, colon cytokine expression level, colon mucosal VDR expression level, colon epithelial cell proliferation and apoptosis level of each group of mice were compared. In the in vitro experiment, HCT116 cell line was stimulated with p40 to evaluate the cell VDR expression level and proliferation level.
Comparison of severity of colitis in Vdr+/+ mice treated with vitamin D3 and Lactobacillus rhamnosus LGG alone or in combination
Comparison of vitamin D receptor (VDR) expression and colonic epithelial proliferation/apoptosis in colitis epithelial cells of VDR+/+ mice treated with vitamin D3 and Lactobacillus rhamnosus LGG alone or in combination
Comparison of severity of colitis and colonic epithelial proliferation/apoptosis in Vdr-/- mice treated with vitamin D3 and Lactobacillus rhamnosus LGG alone or in combination
Comparison of vitamin D receptor (VDR) expression and colonic epithelial proliferation/apoptosis in colitis epithelial cells of VDR+/+ mice treated with vitamin D3 and p40 alone or in combination
Effect of p40 stimulation on vitamin D receptor (VDR) expression in HCT116 cells
How to effectively supplement it?
Supplement vitamin D3 preparations
If your body is deficient, you can supplement with vitamin D3 preparations.
Ensure sun exposure
The body synthesizes it through sunlight exposure, so to prevent deficiency, try to get 15-20 minutes of sunlight a day.
Supplement vitamin D3 through food
In addition to obtaining it through sun exposure, it can also be supplemented through food, but the content is relatively small, including wild salmon, sardines, etc. In addition, eggs and mushrooms also contain relatively small amounts.
Vitamin D3: The "sunshine guardian" that stabilizes blood sugar
Improve insulin secretion and sensitivity: It can regulate calcium channels on pancreatic beta cells, thereby affecting insulin secretion. It can regulate the influx of calcium into cell membranes and the concentration of free calcium in the cytoplasm, activate calcium ion pathways, and promote normal insulin secretion. In addition, it can reduce insulin resistance, enhance insulin sensitivity, and make blood sugar more stable.
Reduce insulin resistance: Studies have shown that it can effectively reduce the insulin resistance level (HOMA-IR) of patients with type 2 diabetes, which is very helpful for blood sugar control. Vitamin D deficiency is considered an important factor in the development of insulin resistance, so supplementing it can help solve this problem.
Prevent the occurrence and development of diabetes: Some prospective studies have found that taking a higher dose of vitamin D can reduce the risk of adult patients with prediabetes developing type 2 diabetes and help restore normal blood sugar regulation. It may protect pancreatic cells by inhibiting inflammatory reactions and regulating the body's immunity, thereby preventing the occurrence and development of diabetes.
Improve sugar metabolism: By regulating mechanisms such as autophagy activity, optimize the sugar metabolism process and maintain blood sugar stability.
Product application range
Functional food and health products
With the increasing awareness of health, the functional food and health products market is booming. As one of the key nutrients, it is widely used in a variety of functional products such as bone health, immunity improvement, cardiovascular health, etc., to supplement supplements that meet specific populations or specific health needs.
Dairy fortification
Dairy products are one of the main carriers of Bulk Vitamin D3 Powder fortification. By adding appropriate amounts to milk, yogurt, cheese and other dairy products, the nutritional value of the product can be significantly improved and the dual needs of consumers of different ages for calcium and vitamin D can be met. Especially for infant formula milk powder, it is generally required internationally to prevent the occurrence of skeletal diseases such as rickets.
Formulation Of Tart Cherry Powder Bulk
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YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Bulk Vitamin D3 Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.
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