Polygonatum Extract

What is Polygonatum sibiricum extract?

Polygonatum extract of Polygonatum sibiricum Red. or Polygonatum cyrtonema Hua. It is processed by extraction, filtration, concentration, drying and other processes. It contains various nutrients and active ingredients such as Polygonatum sibiricum polysaccharide, amino acids, steroidal saponins, quinone components, zinc, iron, selenium, niacin, etc. Among them, Polygonatum sibiricum polysaccharide and steroidal saponins are its main active ingredients. It has the effects of replenishing qi and nourishing yin, strengthening the spleen, moistening the lungs, and benefiting the kidneys. It is used for spleen and stomach weakness, fatigue, dry mouth and less food, lung deficiency and dry cough, lack of essence and blood, and internal heat and thirst.

It is a plant extract widely used in traditional Chinese medicine and modern health supplements, and has attracted attention for its multiple pharmacological effects.

What functions does it have?

Inhibit lipid peroxidation and scavenge oxygen free radicals

Anti-aging active ingredients exist in the extracts and monomer compounds of Polygonatum sibiricum, which can inhibit the generation of spontaneous or induced lipid peroxidation product malondialdehyde, have a direct scavenging effect on oxygen free radicals, and prevent the decrease of superoxide dismutase SOD and glutathione peroxidase GSH-Px content, thus playing an anti-aging role.

Anti-inflammatory

Polygonatum sibiricum polysaccharide can significantly reduce the levels of pro-inflammatory factors interleukin-6 and tumor necrosis factor-α in cells, inhibit the expression and secretion of inflammatory pathway-related protein NF-κB, which also helps anti-aging, because the inflammatory response is closely related to the aging process.

Anti-aging

Polygonatum sibiricum polysaccharide, the main biologically active ingredient of Polygonatum sibiricum, has significant K oxidation, anti-fatigue, and delayed collective aging effects. Cellular aging is often accompanied by the generation of aging-related secretory phenotypes, which are mainly composed of a series of growth factors, chemokines and inflammatory factors, among which inflammatory factors such as IL-6 and TNF-α are closely involved in the aging process. Many studies have shown that Polygonatum sibiricum polysaccharide can affect the expression of IL-6 and TNF-Αde, indicating that Polygonatum sibiricum polysaccharide affects the aging process of cells by intervening in the aging-related secretory phenotype, thereby achieving the effect of K aging.

Anti-pathogenic microorganisms

It can inhibit certain pathogenic microorganisms, such as Salmonella typhi, Staphylococcus aureus, acid-fast bacilli and common pathogenic fungi.

Replenishing Qi and Red Yin

It has the effect of replenishing Qi and nourishing Yin, which can enhance the body's Qi and blood circulation and improve symptoms such as fatigue and tiredness caused by Qi deficiency

Strengthening the spleen and moistening the lungs

It has a good nourishing effect on the spleen and stomach, and can improve symptoms such as loss of appetite and indigestion caused by spleen and stomach weakness.

Moistening the lungs

Polygonatum extract can also moisten the lungs and relieve coughs, and has a significant relieving effect on symptoms such as lung deficiency and dry cough, dry cough and less sputum.

Tonifying the kidneys

It can nourish the kidneys and replenish essence, and has a good improvement effect on symptoms such as low back pain, five heart irritability, premature graying of hair, and internal heat due to yin deficiency. In addition, Polygonatum sibiricum extract also has a certain hypoglycemic effect, and has a certain auxiliary therapeutic effect on diabetic patients.

Enhance immune function

Modern medical research shows that Polygonatum sibiricum extract can enhance the body's immune function and improve the body's disease resistance.

Regulate blood sugar

It can counteract the hyperglycemia caused by adrenaline. Experiments show that Polygonatum sibiricum extract has the effect of first increasing and then decreasing the blood sugar content of rabbits.

Cardiovascular protection

It has a certain counteracting effect on myocardial ischemia, and can counteract the increase in T waves caused by posterior pituitary hormone, and promote the early recovery of abnormal T waves.

Help you to fight oxidation and lower blood sugar

At present, the global incidence of diabetes is increasing year by year, and it has become a global public health problem. More and more scholars are paying attention to the role of natural product sources in lowering blood sugar and anti-oxidation. Polygonatum sibiricum is a Chinese medicine with both medicinal and edible properties. Polygonatum sibiricum, Polygonatum yunnanensis and Polygonatum sibiricum are the three main original plants. Polygonatum sibiricum has a variety of bioactive compounds, such as phenols and flavonoids, which have multiple biological properties such as antioxidant, anti-aging, anti-inflammatory, and hypoglycemic. At present, the hypoglycemic and anti-proliferative effects of Polygonatum sibiricum polysaccharides and steroidal soaps have been widely studied.

Total phenols and total flavonoids of Polygonatum sibiricum extract

Antioxidant activity of Polygonatum sibiricum extract

Effects of different concentrations of extracts on the viability of HepG2 cells.

Antioxidant activity on HepG2 cells. (a) ROS level; (b) MDA content; (c) SOD activity.

Inhibitory effect on α-glucosidase activity.

Effects of different extracts and acarbose on blood glucose after intragastric administration of sucrose. (a) Blood glucose content; (b) Area under the blood glucose curve.

The results showed that the total phenols and flavonoids in Polygonatum sibiricum had antioxidant activity and inhibited the activity of α-glucosidase. Among them, the ethanol extract had the strongest scavenging and reducing power for DPPH and ABTS free radicals.

What can it be used for?

Medicine

It is often used to treat some diseases, such as hypertension, coronary heart disease, leukopenia, aplastic anemia, drug-induced deafness, etc. It has anti-pathogenic microbial effects, and in vitro tests show that it has inhibitory effects on certain bacteria and fungi. It has an effect on blood sugar and can reduce hyperglycemia caused by adrenaline. It also has a certain effect on the cardiovascular system, such as combating myocardial ischemia and improving mice's tolerance to hypoxia.

Food and health products

As a food additive, it can be used to increase the nutritional value of food, such as providing nutrients such as polysaccharides and amino acids.

In the health care product industry, it may be used to make tonics because it is considered to have a tonic effect.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Polygonatum Extract and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Packaging and Shipping

Our Company and Factory