phinebut powder

What is Finibut powder?

The chemical name of Finibut powder is 4-amino-3-phenylbutyric acid, which is a white crystalline powder, easily soluble in water, soluble in ethanol, and hygroscopic. It is an acidic compound that can react with alkali to form the corresponding salt. It is stable at room temperature, but may decompose at high temperatures.
It is often used to prepare antidepressants and is a very important pharmaceutical intermediate that can be used in laboratory research and development processes and chemical pharmaceutical production processes. It is often used in the preparation of drugs and dyes. It is an important intermediate that can synthesize antibiotics and other organic compounds. It can also be used as a component of bactericides and adhesives.

Preparation method:

1. Benzoyl chloride and ethyl acetoacetate are used as raw materials. After condensation and hydrolysis of ethyl acetoacetate, benzaldehyde and nitromethane are condensed to form trans-nitrostyrene. Then the two are added by Micheal addition. The addition product is then hydrogenated with Raney nickel catalysis, and finally hydrolyzed in concentrated hydrochloric acid to form phenibut.
2. It can be prepared by the reaction of phenylbutanone and ammonium sulfite. First, phenylbutanone and ammonium sulfite are added to the reactor, then reacted under acidic conditions, and finally purified to obtain the product.

Effect:

It can relieve anxiety and stress and promote sleep. In addition, it also helps to improve memory and attention, induce relaxation and reduce muscle tension.
It is a nutritional supplement, a synthetic derivative of GABA, a neurotransmitter that is primarily inhibitory in nature. Its chemical structure is essentially made up of GABA molecules connected to a phenyl molecular ring. When ingested as a supplement, GABA itself cannot cross the blood-brain barrier to any great extent. But by adding the phenyl ring as a delivery system, it allows the compound to pass from the blood and interact directly with neurons in the brain. This increases the activity level of GABA in the brain, where it better regulates overexcitement and anxiety. It is used to promote relaxation, improved mood, and easier sleep. Some studies have even found that it may have a positive effect on attention and mental ability.

Efficacy:

1. Reduce anxiety and stress
One of the main effects is to reduce anxiety and stress levels, a benefit that has been proven by multiple clinical and laboratory studies. Once in the brain and central nervous system, it acts similarly to GABA, mainly targeting those neurons or nerves that are overexcited and firing quickly. Taking phenibut powder can reduce the rate of excitation of these neurons, allowing them to respond only to the most important stimuli.
2. Improve sleep quality
It is also commonly used to solve sleep problems. It may help regulate normal sleep patterns and even increase the time spent in the REM sleep stage (i.e. the most restful and healthful sleep stage). This supplement can reduce insomnia and has even been used to treat restless legs syndrome.
3. Improve attention and mental ability
Some studies have even found that it may have a positive effect on attention and mental ability.

Relationship with GABA:

GABA is a major inhibitory neurotransmitter in the brain. Its role in fast inhibitory synaptic transmission through exocytosis-mediated presynaptic GABA release and postsynaptic low-affinity GABA A receptor (GABA A R) activation has been the main focus of subsequent research. The regulation of activity state consists of three main processes: biosynthesis, release, and clearance. Biosynthesis, which is mainly synthesized by decarboxylation of glutamate or degradation of putrescine, is the main factor regulating the activity state of GABA. In particular, the synthesis of GABA in astrocytes contributes significantly to the activity state of GABA in the brain.
Phenibut is a synthetic derivative of GABA. Although both are neurotransmitters, there are some differences between them. They play different roles in the brain. GABA biosynthesis occurs mainly in astrocytes, while phenibut is artificially synthesized. GABA is mainly responsible for fast inhibitory synaptic transmission, while phenibut increases the activity level of GABA in the brain to better regulate overexcitement and anxiety. Although there are some differences between them, they both have important effects on the function of the brain.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Finibut powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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