Pepsin Powder

Introduction

Pepsin Powder is synthesized by the chief cells of the gastric glands and is also an important proteolytic enzyme. Its active site contains two aspartic acid residues, one of which is in a dissociated state and the other is not, with an optimal pH of 2~3. It mainly acts on the peptide bonds formed by hydrophobic amino acids, especially aromatic amino acid residues, at the P1 and P1′ sites. It is a biological molecule that plays a key role in the human digestive process. It is carefully produced and secreted by special cells of the gastric mucosa, the acid-secreting cells. The main function is to break down the protein in food and convert it into small molecule peptides and amino acids that are easily absorbed. This enzyme plays a vital role in the human body's nutrient absorption process. This process is a model of precisely regulated biochemical reactions in organisms, demonstrating the exquisite mechanism of living organisms adapting to the environment.

Product Details Table

Features

Activity depends on gastric acid

Pepsinogen is inactive and needs to be converted into active enzymes under the action of gastric acid (pH value is about 1.0-5.0).

Specificity

It has a preference for peptide bonds of specific amino acid sequences, and mainly hydrolyzes peptide bonds with aromatic amino acids or leucine at the amino or carboxyl ends.

Environmental stability

It is stable in an acidic environment, helps maintain the acidic environment in the stomach, helps digest food and prevents harmful bacteria from overgrowing in the stomach.

Digestive function

The main function is to initially digest proteins and break them down into smaller polypeptide fragments, which are then further digested and absorbed in the small intestine.

Function

Promote protein digestion

It can break down the protein in food into smaller peptides and amino acids. These small molecules are more easily absorbed by the small intestine, thus ensuring the effective utilization of protein.

Maintain a stable gastric environment

Pepsin Powder helps maintain the acidic environment in the stomach, which not only helps digest food, but also inhibits the growth of harmful bacteria in the stomach and protects the health of the stomach and small intestine.

Promote nutrient absorption

By helping protein decomposition, it creates favorable conditions for the small intestine to absorb other nutrients, thereby improving the overall nutrient absorption efficiency.

Participate in immune regulation

It can break down foreign protein antigens, reduce immune stimulation to the human body, and interact with the intestinal immune system to help maintain immune balance.

Relieve indigestion

For indigestion caused by excessive protein intake or weakened gastrointestinal function, it can help break down protein, reduce the burden on the stomach, and relieve symptoms such as early satiety, acid reflux and abdominal pain.

Specific Working Principle

First, the chief cells of the gastric mucosa secrete pepsinogen, which is activated only after combining with gastric acid to digest protein. In other words, a strong acidic environment is the condition for its production. After the zymogen is activated, it specifically breaks down protein.

Applications

Food

In the field of food processing, it is used to process food raw materials to improve the taste and nutritional value of food. For example, in the process of making cheese and soy sauce, it can help break down proteins and improve the texture and flavor of the product.

Medicine

In medicine, it is mainly used to make various pharmaceutical preparations, especially those that require protein hydrolysis.

Feed

It is also used as a feed additive, especially in the breeding industry, to help animals digest and absorb protein more easily, thereby improving feed conversion rate and animal production performance.

Extraction Method

Acid extraction is relatively simple, but the extracted protein is already activated and has low stability.

Alkaline extraction is not yet activated, and the obtained protein is relatively stable, but the extraction time is long and there are many impurities. Despite this, most of the extractions are done by alkaline extraction, which is conducive to the study of the activation properties of the zymogen and long-term preservation.

Separation and purification process:

1. Extraction;

2. Salting out precipitation, this step can be assisted by membrane separation method;

3. Ion exchange chromatography and gel filtration chromatography. The crude enzyme solution is generally separated by salting out precipitation method, and is assisted by ultrafiltration membrane separation to remove salt and most impurities, and at the same time, the purpose of concentration can be achieved. Next, the combination of gel column and ion exchange column is used for further purification, which can make the purity of pepsin above 95%.

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Pepsin Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Packaging and Shipping

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