Niacinamide Bulk Powder

What is Niacinamide Powder?

Niacinamide bulk powder, also known as vitamin B3, is a water-soluble vitamin that belongs to the B vitamins. It is an amide compound of niacin and is a white crystalline powder. As a medicinal ingredient, it has high safety. It is also a basic vitamin in clinical dermatology treatment. It can effectively treat skin problems such as photosensitive dermatitis and acne.

Nicotinamide (NAM) is the amide form of niacin and one of the precursors of nicotinamide adenine dinucleotide. It can be used as a dietary supplement or clinical treatment drug to supplement NAD+ levels in the body and participate in key functions such as cell metabolism and DNA repair. Niacinamide powder also has multiple biological functions such as antibacterial, anti-inflammatory, and regulating cellular immunity, and has a significant improvement effect on skin diseases, neurodegenerative diseases, etc.

Niacinamide bulk powder is the form of niacin in the human body. Niacin and nicotinamide together are called vitamin PP, and they are both B vitamins. Niacin is also called niacin, and nicotinamide is also called nicotinamide. Niacin and nicotinamide have similar physiological activities in the human body. Both can promote cell metabolism. As drugs or nutritional supplements, both can be used to prevent and treat roughness. But niacin has the effect of dilating blood vessels and lowering blood lipids, while nicotinamide has no such effect.

The mechanism of action of nicotinamide

Niacinamide powder is well-known for its whitening effect. Unlike the common whitening mechanism that inhibits tyrosinase, nicotinamide mainly inhibits the transfer of melanosomes from melanocytes to keratinocytes. In other words, it cuts off the transfer path of melanin. Achieve whitening effect. In addition, it can accelerate the metabolism of melanin keratin and enhance its whitening effect; it can also maintain skin moisture, promote microcirculation in the dermis, and strengthen the skin barrier.

Niacinamide for skin care

In 1974, Girish, Parsad, Mathur and others in the UK first discovered that combining nicotinamide and sunscreen into a cream system could absorb ultraviolet rays to prevent tanning and sunburn. Since then, many scientific research institutions have begun to pay attention to its application in the field of cosmetics. At first, nicotinamide was gradually promoted as a whitening ingredient. Later studies found that nicotinamide also has anti-aging, pore shrinking, and acne removal effects.

01 Anti-glycation, improve skin tone

The whitening mechanism of nicotinamide includes three aspects: inhibiting the formation of melanin granules, inhibiting the transmission of melanin to keratinocytes, accelerating the transfer of melanin in keratinocytes to the stratum corneum, and promoting the shedding of the stratum corneum. At the same time, nicotinamide also has the effect of anti-glycation. During the aging process of skin, the contents of NADH (reduced coenzyme I) and NADPH (reduced coenzyme II) gradually decrease, and both control the entire process of intracellular synthesis and decomposition. High levels of NADPH exert a powerful antioxidant effect and prevent the spontaneous glycosylation reaction of proteins and sugars. The glycated proteins produced by the glycosylation reaction will be deposited in the dermis, causing the skin to appear yellowish-brown.

As the precursor of NADH and NADPH, Pure niacinamide powder can play a role by regulating the balance of their levels in the body; nicotinamide can significantly increase the content of NADPH to exert an anti-glycation effect, thereby diluting the yellow color of protein glycation and brightening skin color.

02 Strengthen skin barrier and fight aging

Ceramide is an important component of the skin barrier. Niacinamide enhances the skin barrier function by increasing the ceramide content in the stratum corneum, reducing transepidermal water loss and improving skin resistance. In addition, nicotinamide can also promote the synthesis of proteins in the epidermis, so nicotinamide is also widely used in anti-aging skin care products. Long-term use of skin care products containing nicotinamide can improve skin texture and significantly reduce fine lines and wrinkles.

03 Balance oil secretion and shrink pores

A considerable number of enlarged pores are caused by excessive secretion of oil in the skin. Pure niacinamide powder can significantly inhibit the production of sebum and make the secretion of sebum more appropriate and even. As oil secretion decreases, the pores, the channels through which the skin excretes sebum, will also slowly shrink, achieving the effect of shrinking pores.

04 Anti-inflammatory and anti-acne

Research shows that gel containing 4% nicotinamide is as effective in treating acne as 1% clindamycin gel. At present, the anti-inflammatory mechanism of nicotinamide is not clear. It may achieve anti-inflammatory effects by inhibiting the release of histamine from mast cells, inhibiting leukocyte chemotaxis and secretion of inflammatory mediators, blocking histamine receptors, and inhibiting the transfer of lymphocytes. effect.

Precautions for Niacinamide

01 Skin irritation of nicotinamide

Although niacinamide is very powerful, it is often criticized for its irritation. When using high-concentration nicotinamide products, many people will experience skin intolerance and allergic reactions such as redness, swelling, itching, and stinging. The concentration of nicotinamide is below 2%, and the absorption rate increases with the amount added. It is linear. When the concentration reaches 2%, the absorption rate will not increase linearly. However, as the concentration of nicotinamide added increases, the effect is better, but the irritation will also increase. When choosing niacinamide products, you should start with low concentrations. If your skin can tolerate it, then gradually choose higher concentration niacinamide products. Before using high-concentration niacinamide, first use moisturizing lotion to moisturize the skin and adjust the skin to the best condition to slow down the penetration of niacinamide into the skin and reduce irritation.

02 Niacinamide cannot be mixed with ingredients whose pH value is acidic!

The cause of niacinamide intolerance is mostly due to niacin. Niacinamide has the best stability in solutions with a pH value of 6. In solutions with a pH value higher or lower than 6, it will be hydrolyzed to form niacin. Niacin will increase the rate of adverse skin reactions, so it contains nicotinamide. Formulated products generally control the pH value between 5 and 7 to reduce the formation of niacin. Therefore, niacinamide products are not suitable to be mixed with other acid products. If mixed, the pH value of the skin will change, and niacinamide will release a large amount of niacin, causing irritation to the skin.

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YTBIO is committed to providing customers with the highest-quality Pure niacinamide Powder bulk and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needs about our products, please feel free to contact us, and we will reply to you as soon as possible.

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