Glycerophosphocholine

What is Glycerophosphocholine?

Glycerophosphocholine, or GPC, is a type of choline used to enhance cognitive ability and increase power output through its effects on growth hormone production. It is a water-soluble small molecule that normally exists in the human body and is a biosynthetic precursor of the important neurotransmitter acetylcholine.

It is a biosynthetic precursor of the key neurotransmitter acetylcholine, a product of hydrolysis of two fatty acid chains on the lecithin molecule in the human body, and is present in all mammalian cells. It is mainly found in soy lecithin and other plants and is used to make cognitive health supplements and enhance muscle strength. GPC is highly hydrophilic and can be rapidly absorbed after oral administration. It is a precursor of acetylcholine (ACh) and has broad prospects in the treatment of cholinergic dysfunction.

Product Details List

Effects of Glycerophosphocholine

GPC rapidly crosses the blood-brain barrier, protects neurons and improves brain function and learning processes. In particular, through its mechanism of action, it directly increases the synthesis and secretion of acetylcholine, superior to any other choline-related compound, affecting choline concentrations throughout the system and brain.

Due to its structural characteristics, GPC contributes to the synthesis of cell membrane phospholipids, thereby enhancing the fluidity of cell membranes, and also has a positive effect on lipid metabolism.

In addition, GPC can increase the expression level of genes and prevent cognitive decline caused by aging, which also makes GPC have a significant effect in the treatment of mental diseases such as Alzheimer's disease, amnesia, and cerebral ischemic stroke.

Function

Antioxidant: It has strong antioxidant capacity, can remove free radicals in the body, reduce the release of inflammatory factors, thereby fighting brain inflammation and protecting the brain from oxidative stress.

Enhance brain power and cognitive function: It can increase the level of acetylcholine in the brain, thereby enhancing memory and learning ability. It helps improve the overall function of the brain by promoting the rapid transmission of signals between nerve cells, which is particularly important for preventing cognitive decline.

Regulate mood: Glycerophosphocholine can promote the release of dopamine, improve the neurotransmission of dopamine in the brain, and increase the level of 5-hydroxytryptamine in the striatum and prefrontal cortex, which helps to relieve insomnia and stabilize mood.

Promote fat burning and lipid metabolism: Due to the role of choline as a lipophilic nutrient, GPC helps the fat burning process and supports lipid metabolism, ensuring that cell mitochondria can effectively use fatty acids and convert them into ATP or energy.​​​​​​​

Protect nerves: It can promote the secretion of neurotrophic factors and activate the relevant signaling pathways for cell survival, thereby exerting a neuroprotective effect. In addition, it can also maintain physical health by increasing growth hormone levels.

Applications

Food

It can be used as an emulsifier, stabilizer and other food additives to improve the taste of food and extend the shelf life.

Health products

It is made into various health products, such as dietary supplements, beverages, soft candies, etc., which claim to improve memory and cognitive function, improve motor function, etc.

Cosmetics

Due to its moisturizing and repairing properties, it can be used as an ingredient in skin care products to help improve skin condition and maintain skin health.

Medicine

GPC is an important biosynthetic precursor of the neurotransmitter acetylcholine, which can promote the synthesis of acetylcholine in the brain, enhance the body's memory and cognitive ability, and prevent Alzheimer's diseases.

Preparation Method

1. At 25℃ and -0.09MPa, slowly add 140g of phosphoric acid (dropping speed is 10 drops/s) to 100g of choline chloride crude product (containing 70% choline chloride), and after the addition is completed, heat it to 70℃ and perform vacuum distillation until there is no distilled water, then heat it to 120℃ and control the pressure at -0.09MPa to react for 6h, and then add 50g of water to terminate the reaction to obtain a phosphorylcholine chloride mixture;
2. At 25℃, 100g of the above phosphorylcholine chloride mixture is mixed with 3000g of calcium hydroxide aqueous solution (the mass fraction of calcium hydroxide is 1 5%) for 10 minutes until the pH of the system reaches 8 to obtain a double decomposition mixture;
3. At 25°C and 35Pa, the double decomposition mixture is subjected to reduced pressure distillation until solids are precipitated to obtain a solid-liquid mixture;
4. The solid-liquid mixture is cooled to -5°C for crystallization for 40 minutes, then filtered and dried at 100°C for 2 hours to obtain 100g of phosphorylcholine chloride calcium salt tetrahydrate (purity is 100%);
5. The filtrate is recrystallized at -5°C for 40 minutes, then filtered and dried at 100°C for 2 hours to obtain phosphorylcholine chloride calcium salt tetrahydrate.

Formulation Of Glycerophosphocholine

Capusle Formulation

Tablet Formulation

Solid Drink Formula

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Glycerophosphocholine and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Packaging and Shipping

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