Fibroin Powder

What is fibron?
Silk protein, also known as fibroin, is a natural high-molecular fiber protein extracted from silk. It accounts for about 70% to 80% of silk and contains 18 kinds of amino acids, of which glycine (Gly), alanine (Ala) and serine (Ser) account for more than 80% of the total composition. Leucine can accelerate cell metabolism, serine and threonine can delay skin aging, and tryptophan and tyrosine can absorb ultraviolet rays. It is non-toxic, non-allergenic and non-irritating to the human body, safe and reliable, and has good biocompatibility comparable to collagen.

Applications

As an excellent natural moisturizing factor, it has a natural moisturizing function that is beneficial to skin care and has a good sun protection effect. It also has antioxidant and skin cancer inhibitory effects. It can be used as a raw material for skin care and beauty cosmetics. Since it can increase the water content of the skin's stratum corneum, promote collagen synthesis, enhance the skin's tension and elasticity, promote pigment decomposition, and even out skin color, regular use of it beauty skin care products can make the skin white, moisturized, shiny, and elastic, and has a significant improvement on gray, dull, dry lines, and loose skin problems.

Benefits

At present, the most commonly used and most powerful moisturizing ingredient on the market is hyaluronic acid. Taking it as an example, although it has a strong moisturizing function and certain anti-aging and anti-inflammatory effects, compared with it, it obviously has more functions. Not only does it have the same strong moisturizing effect, it can also effectively inhibit the formation of tyrosinase, with an average UVB resistance of up to 90%, and an anti-UVA resistance of more than 50%, that is, it has both strong whitening and UV resistance. For most skin care products, there are very few ingredients that can simultaneously have moisturizing, whitening, anti-wrinkle, sun protection, and anti-inflammatory properties. Therefore, it can be said to have thousands of functions in one, and it still has a high application prospect in today's skin care market where competition is so fierce.

Function
1. Moisturizing function: It has a strong skin affinity. When it forms a film on the skin surface, it can not only absorb moisture when the external humidity is high, but also release moisture when the external environment is dry, so that our skin always maintains the best moisture content. When your skin barrier is damaged, you need a natural, non-irritating and well-moisturizing product to help you repair your skin.
2. Anti-wrinkle function: It is called the "Queen of Fibers". Its fibrous protein can enhance skin elasticity, accelerate skin metabolism, and prevent the formation of wrinkles.
3. Anti-aging function: Collagen is the main reason to ensure that the skin will not age, but once collagen is lost, it cannot be regenerated. The main amino acids of It are very similar to collagen. At this time, it can accelerate cell metabolism, repair the stratum corneum, delay skin aging, and slow down aging.
4. Sun protection function: Tryptophan and tyrosine play their greatest role, greatly reducing the damage of ultraviolet rays to our skin. Not only can it protect against the sun, but long-term use can also delay the aging caused by photoaging.
5. Whitening function: It can inhibit the formation of melanin in the skin. With less melanin and sun protection function, the skin will naturally become fair and delicate.
6. Hair care function: It is hydrolyzed into silk peptides. Silk peptides have good film-forming properties and can give hair a glossy and moisturizing feel. It protects the hair from external chemical damage and thermal damage, provides the nutrients needed by the hair, moisturizes the hair and provides the required nutrients.

Biological characteristics 
1. Biodegradability
Using hexafluoroisopropanol to dissolve silk solution as spinning solution and ethanol as coagulation solution for wet spinning, medical regenerated silk fiber that can be effectively biodegraded can be obtained.
2. Cytocompatibility
The regenerated  membrane was obtained by dissolving silkworm cocoon shells with LiBr solution, which can support cell adhesion and growth; the culture of a series of cells such as glial cells, epithelial cells, keratinocytes, endothelial cells, fibroblasts and osteoblasts on  it nano non-woven fabrics was investigated, and it was found that the cell morphology was normal and the growth was good.
3. Biosafety
The cell proliferation experiment and hemolysis experiment were used to study the cytotoxicity and hemolysis reaction of the medical silk fibroin regeneration membrane, and it was found that the regeneration membrane used had no obvious cytotoxicity. The reaction of silk non-woven mesh implanted in the body was studied, and it was found that there was no obvious lymphocyte infiltration within 6 months after it was implanted subcutaneously.

Extraction process 
① Degumming of cut cocoons and waste silk: remove the impurities in the peeled cocoons of the cut cocoons of the silkworm seed farm or the waste silk of the silk reeling factory, then boil them in a certain concentration of weak alkaline solution for half an hour, take out the cocoons and rinse them with water several times and wring them dry (degumming).
② Hydrolysis: strictly control the reaction temperature, bath ratio, time, solvent concentration and other conditions, and stop the hydrolysis in the form of polypeptides.
③ Filtration and purification: filter out solid substances and impurities that are not completely hydrolyzed.
④ pH adjustment: adjust the pH to about 6.5~7.0 with a pH regulator.
⑤ Concentration: Concentrate the hydrolyzate after pH adjustment on a membrane concentrator.
⑥ Sterilization: (If the concentrated hydrolyzed protein solution is used in food, it will continue to be enzymatically hydrolyzed with enzyme preparations, and the molecular weight will be controlled to be stopped at about 300~800, and then sterilized.) Add a trace amount of preservatives to prevent the growth of mold.
Indicators of silk protein

Technical indicators:
①Appearance: light yellow transparent liquid, no special smell, easily soluble in water.
②Biuret reaction is positive.
③pH value 6~7.
④Protein content:>/14%.
⑤Amino acids: 17 kinds in total, more than 87mg per ml.
⑥Ash content: less than 1%.
⑦Heavy metals mercury, arsenic, and lead are less than 1ppm respectively.
⑧Total number of bacteria (individuals/m1) ≤10.

Quality indicators: Silk protein is a protein extracted from silk. It has good biocompatibility and can be prepared into materials in various forms such as membranes, gels, and microcapsules. Due to its unique physical and chemical properties, silk protein materials are currently widely studied in the field of biomedical materials, such as immobilized enzyme materials, cell culture matrices, drug sustained release agents, artificial organs, etc.

Formulation
Capusle Formulation
 

Tablet Formulation
 

Solid Drink Formula
 

Certificates

Yuantai Organic Bio is committed to providing customers with the highest-quality bulk fibroin and services so that every consumer can enjoy natural, healthy, and high-quality food. If you have any inquiries or needsabout our products, please feel free to contact us, and we will reply to you as soon as possible.
 

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