Bulk Diindolylmethane Powder

What is Diindolylmethane?

Bulk Diindolylmethane Powder, or DIM for short, is a naturally occurring compound found in cruciferous vegetables like broccoli, cauliflower, cabbage, kale, and more. Therefore, eating these foods can provide your body with DIM. Diindolylmethane also comes in supplement form and is thought to provide a variety of health-boosting benefits. Containing a compound called indole-3-carbinol, a chemical reaction occurs when indole-3-carbinol enters an acidic environment, converting it to DIM, which has a variety of amazing benefits. Some trials have shown that it supports healthy estrogen levels and may reduce certain estrogen-related diseases.

Functions of diindolylmethane

• Ability to interact with estrogen and testosterone receptors to help maintain hormone balance. This is particularly beneficial for treating PCOS, menopausal symptoms, and hormonal acne.
• It has significant anti-inflammatory ability and helps regulate inflammatory responses by inhibiting the release of inflammatory mediators.
• It has certain antioxidant activity and can neutralize free radicals and prevent the harmful effects of oxidative stress, thus helping to reduce oxidative stress.
• DIM weight loss supplements may help maintain a healthy weight. It improves glucose tolerance, reduces body weight, and reduces fat accumulation in mice fed a high-fat diet.
• It can regulate estrogen metabolism and prevent estrogen levels from sharply increasing or decreasing, thereby maintaining the relative balance of the body.
• It inhibits adipogenesis through an AMPKα-dependent mechanism, and has an inhibitory effect on adipogenesis in adipocytes and Caenorhabditis elegans.
• Neuroprotective effects against ischemia include inhibition of apoptosis and autophagy, which are dependent on HDAC and AhR/CYP1A1, but not ERα/CYP19A1 signaling.
• Improvement of intestinal permeability dysfunction in cultured human enterocytes and model animals.
• It has the effects of sedation, sleep aid, and anticonvulsant, and can be used to treat insomnia, neurasthenia and other diseases.
• It has a certain detoxification effect and can be used for detoxification treatment after eating poisonous food.

3,3′-Diindolylmethane induces G1 arrest and apoptosis in human acute T-cell lymphoblastic leukemia cells

Effects of DIM treatment on CEM cells cultured in vitro

I3C and DIM reduce proliferation and viability of CEM cells

Comparison of I3C and DIM in various human TALL cell lines

DIM induces cell cycle arrest in CEM and HSB2 cells

DIM reduces the expression of cell cycle regulatory proteins

DIM induces apoptosis in human T-ALL cells

DIM induces apoptosis in CEM cells detected by TUNEL

Effects of DIM and I3C treatment on growth of CEM xenografts

DIM and 13C inhibit growth of CEM cell xenografts

DIM induces apoptosis in vivo

Application areas

Medicine

DIM also plays an important role in hormone regulation. It is often used to regulate estrogen levels and help relieve estrogen-related symptoms such as acne, premenstrual syndrome, mood swings, menopausal symptoms, etc. In addition, DIM may also be used to prevent the side effects of testosterone supplementation. It is also used to lose weight, prevent thyroid disease, and treat male breast development.

Food field

Food additives: DIM has antibacterial and anti-biofilm properties, which makes it a potential application prospect in the food industry, such as as a new biofilm inhibitor.

Functional food: Due to the various health benefits of DIM, it is also developed into a functional food ingredient to help regulate hormone levels in the body and improve health.

Formulation Of Diindolylmethane

Capusle Formulation

Tablet Formulation

Solid Drink Formula

Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Bulk Diindolylmethane Powder and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

Packaging and Shipping

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