Ascorbyl tetraisopalmitate Liquid

What is Ascorbyl Tetraisopalmitate Liquid

Ascorbyl Tetraisopalmitate Liquid is a light yellow to colorless liquid. It is an esterified vitamin C derivative and the most precious one among vitamin C derivatives. It penetrates into the skin and is converted into vitamin C to play the role of vitamin C (hence it is also called vitamin C inducer). It has good oil solubility and can be widely and quickly dissolved in esters, vegetable oils, ethanol and hydrocarbons (except polyols). At the same time, it is mild and non-irritating and can also be used on sensitive skin. It is a class of drugs composed of a variety of different mixtures that can inhibit the activity of acidic peptides (DPP-4) and thus play an anti-diabetic role.
It shows excellent performance in stability, transdermal permeability and conversion ability. Its macromolecular structure formed by esterification reaction enables VC-IP to maintain extremely high stability in vitro, and its activity can still remain above 85% after being placed at room temperature for 6 months. Although the molecule is large, its oil-soluble characteristics give it a high affinity with the stratum corneum and enable it to quickly penetrate the cell membrane and have good transdermal performance. VC-IP can be converted into vitamin C in cells, which has antioxidant properties that even surpass the prototype vitamin C. This unique conversion mechanism provides powerful protection and nourishment for the skin.
Product properties:
Excellent transdermal absorption
Inhibits intracellular tyrosinase activity and melanin production
Reduces UV-induced cell/DNA damage (UV protection/anti-stress)
Prevents lipid peroxidation and skin aging (anti-oxidation)
Good solubility in common cosmetic oils
SOD-like activity (anti-oxidation)
Collagen synthesis and collagen protection (anti-aging)
Stable to heat and oxidation
Main effects
Excellent transdermal absorption: It can effectively penetrate the skin barrier, and after being absorbed by the skin, it is converted into vitamin C to exert its biological activity.
Inhibit melanin production: It can inhibit the activity of tyrosinase in cells, thereby reducing the production of melanin, and has the effect of whitening and lightening spots.
Antioxidant effect: It can reduce the cell and DNA damage caused by ultraviolet rays to the skin, prevent lipid peroxidation and skin aging, and show strong antioxidant ability.
Anti-aging: It promotes the synthesis and protection of collagen, helps improve skin elasticity and firmness, and reduces the appearance of fine lines and wrinkles.
Thermal and oxidative stability: It remains stable under high temperature and oxidative conditions, which makes it more durable in cosmetic formulas.
Cell metabolism activation: It can activate cell metabolism, promote collagen synthesis, and help skin repair and regeneration.
Treatment of stubborn acne and pigmentation: Long-term use can reduce stubborn acne and facial pigmentation, and improve skin texture and skin tone uniformity.
The unique esterification structure gives it high in vitro stability and good transdermal permeability, and it can be efficiently converted into a powerful antioxidant vitamin C in cells, which is better than the prototype vitamin C. At the same time, the mild nature of VC-IP makes it an ideal choice for consumers who are intolerant to ingredients such as niacinamide, indicating its broad application prospects in the field of beauty and skin care.

Performance Study

With the increasing number of cosmetics containing antioxidant vitamins, studying their stability is crucial to ensuring product quality. The study compared the thermal behavior of ascorbyl tetraisopalmitate and tocopheryl acetate in base cream. Thermogravimetric analysis (TG/DTG) and differential scanning calorimetry (DSC) found that these two vitamins showed good stability below 250°C.
The transmission process of this product in the skin was simulated by molecular dynamics, focusing on its percutaneous absorption. The results showed that the process of VC-IP molecules penetrating through funnel-shaped hair follicles is slower than that through the stratum corneum, and they show higher mobility and lower affinity in the hair follicles. In contrast, VC-IP molecules have a stronger affinity for the stratum corneum and a more direct penetration path.
Cosmetic application scenarios：

Sunscreen and cosmetic formulas containing this product and rice peptides improve the photoaging of young women's skin. Double-blind randomized controlled trials show that it can effectively increase skin moisture, improve skin structure, reduce pigmentation, and accelerate epidermal cell renewal. Daily use of antioxidant formulas containing VC-IP can significantly prevent and alleviate skin problems related to photoaging, especially for young women who do not have the habit of photoprotection.
It is a fat-soluble synthetic derivative of ascorbic acid, mainly used for antioxidant, moisturizing and skin conditioning. As an antioxidant, it can provide photoprotection and is particularly suitable for anti-aging products. This ingredient is widely used in cosmetics such as sunscreens and depigmenting creams.
It can significantly improve the histological characteristics of photoaged skin by reducing free radicals and promoting the synthesis of dermal proteins (such as collagen). Studies have shown that VC-IP plays a key role in reducing the number of skin cell apoptosis and sunburn cells. As an important ingredient in the three-in-one essence, it works synergistically with melatonin and bakuchiol to effectively improve the recovery of skin structure and function and enhance the skin's overall antioxidant capacity.
Clinical evaluation of VC-IP three-in-one facial essence showed that the subjects' skin texture, pigmentation, erythema, skin tone and wrinkles were significantly improved in the continuous use of the essence for 12 weeks and 24 weeks. The wrinkle reduction effect was particularly prominent in the forehead and marionette lines. Although the thickness of the dermis and epidermis increased, it did not reach statistical significance.
Regarding the anti-aging effect and skin tolerance, it showed that VC-IP three-in-one essence can significantly reduce wrinkles, increase skin firmness, and effectively improve skin tone and overall skin quality. The subjects highly praised the beauty properties of the essence, and it showed good tolerance and high safety in various skin types (including oily skin). This result shows that the essence is an effective anti-aging product suitable for a wide range of skin types.
Certificates

YTBIO is developing in an all-round way. We have our own factory, quality inspection and R&D team. We are committed to providing customers with the best quality Ascorbyl Tetraisopalmitate Liquid and services. It is our original intention to let every consumer enjoy high-quality and healthy products. If you have any needs or questions about our products, please feel free to contact us and we will reply you as soon as possible.

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